Glutathione (GSH) and the GSH synthesis gene Gclm modulate plasma redox and vascular responses to acute diesel exhaust inhalation in mice

Inhalation Toxicology

Volumn 25, Issue 8, 2013, Pages 444-454

  Weldy, Chad S ^a   Luttrell, Ian P ^b   White, Collin C ^a   Morgan Stevenson, Vicki ^a   Cox, David P ^a   Carosino, Christopher M ^a   Larson, Timothy V ^a,c   Stewart, James A ^a   Kaufman, Joel D ^a   Kim, Francis ^a   Chitaley, Kanchan ^b   Kavanagh, Terrance J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c University of Washington   (United States)

Author keywords

Diesel exhaust; Glutathione; Lung inflammation; Nitric oxide; Oxidative stress

Indexed keywords

ACETYLCHOLINE; GLUTAMATE CYSTEINE LIGASE; GLUTAMATE CYSTEINE LIGASE C; GLUTAMATE CYSTEINE LIGASE M; GLUTATHIONE; GLUTATHIONE DISULFIDE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; AMINO ACID BLOOD LEVEL; AMINO ACID SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DILATATION; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DNA POLYMORPHISM; EXHAUST GAS; FEMALE; GENETIC ASSOCIATION; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; LUNG ALVEOLUS CELL; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATION; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PARTICULATE MATTER; PRIORITY JOURNAL; REDOX STRESS; RESPIRATORY TRACT INFLAMMATION; TOXIC INHALATION; VASCULAR RING;

ADMINISTRATION, INHALATION; AIR POLLUTANTS; ANIMALS; AORTA; BRONCHOALVEOLAR LAVAGE FLUID; FEMALE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUTROPHILS; NITRIC OXIDE; OXIDATION-REDUCTION; PNEUMONIA; VASODILATION; VEHICLE EMISSIONS;

EID: 84880547439     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958378.2013.801004     Document Type: Article

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