A sensitive LC-MS/MS method for simultaneous determination of six flavonoids in rat plasma: Application to a pharmacokinetic study of total flavonoids from mulberry leaves

Journal of Pharmaceutical and Biomedical Analysis

Volumn 84, Issue , 2013, Pages 189-195

  He, Jun ^a   Feng, Ying ^a   Ouyang, Hui zi ^b   Yu, Bin ^a   Chang, Yan xu ^a   Pan, Gui xiang ^a   Dong, Gai ying ^b   Wang, Tao ^a   Gao, Xiu mei ^a  

^a TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b FIRST TEACHING HOSPITAL OF TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Flavonoids; LC MS MS; Metabolites; Mulberry leaves; Pharmacokinetics

Indexed keywords

ACETONITRILE; ASTRAGALIN; AURANTIIN; FORMIC ACID; ISOQUERCITRIN; ISORHAMNETIN; KAEMPFEROL; QUERCETIN; RUTOSIDE;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; BLOOD SAMPLING; DRUG BLOOD LEVEL; DRUG DETERMINATION; ELUTION; FLOW RATE; IONIZATION; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MULBERRY; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY;

FLAVONOIDS; LC-MS/MS; METABOLITES; MULBERRY LEAVES; PHARMACOKINETICS;

ANIMALS; CHROMATOGRAPHY, LIQUID; FLAVONOIDS; KAEMPFEROLS; LIQUID-LIQUID EXTRACTION; MORUS; PLANT EXTRACTS; PLANT LEAVES; PLASMA; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY; RUTIN; TANDEM MASS SPECTROMETRY;

EID: 84880385756     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.06.019     Document Type: Article

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