Methanol extract of Evodia lepta displays Syk/Src-targeted anti-inflammatory activity

Journal of Ethnopharmacology

Volumn 148, Issue 3, 2013, Pages 999-1007

  Yoon, Ju Young ^a   Jeong, Hye Yoon ^a   Kim, Shi Hyoung ^a   Kim, Han Gyung ^a   Nam, Gyeongsug ^a,b   Kim, Jin Pyo ^b   Yoon, Deok Hyo ^c   Hwang, Hyunsik ^a   Kimc, Tae Woong ^c   Hong, Sungyoul ^a   Cho, Jae Youl ^a  

^a Sungkyunkwan University   (South Korea)

^b Daewoong Pharmaceutical Co Ltd   (South Korea)

^c Kangwon National University   (South Korea)

Author keywords

Anti inflammatory; Evodia lepta (Spreng.) Merr.; NF B; Rutaceae; Src; Syk

Indexed keywords

ANTIINFLAMMATORY AGENT; EVODIA LEPTA EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE SYNTHASE; PHOSPHOTRANSFERASE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROTEIN KINASE SYK; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EVODIA; EVODIA LEPTA; GASTRITIS; MALE; MOUSE; NONHUMAN; PLANT ROOT; PROTEIN TARGETING;

(TNF)-Α; 3-4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE; ANTI-INFLAMMATORY; CMC; COX; CYCLOOXYGENASE; EIA; ELISA; ENZYME IMMUNOASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; EVODIA LEPTA (SPRENG.) MERR.; IΚΚ; IΚB KINASE; IΚBΚ; INDUCIBLE NO SYNTHASE; INHIBITOR OF KAPPA B ALPHA; INOS; LIPOPOLYSACCHARIDE; LPS; MTT; NF-ΚB; NITRIC OXIDE; NO; NUCLEAR FACTOR-ΚB; PG; PHOSPHOINOSITIDE 3-KINASE; PI3K; PROSTAGLANDIN; REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION; RT-PCR; RUTACEAE; SODIUM CARBOXYMETHYLCELLULOSE; SPLEEN TYROSINE KINASE; SRC; SYK; TLR; TOLL-LIKE RECEPTORS (TLR); TUMOR NECROSIS FACTOR;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; DINOPROSTONE; ETHANOL; EVODIA; GASTRITIS; HEK293 CELLS; HUMANS; HYDROCHLORIC ACID; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MACROPHAGES, PERITONEAL; MALE; METHANOL; MICE; MICE, INBRED ICR; NF-KAPPA B; NITRIC OXIDE; PLANT EXTRACTS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS PP60(C-SRC); SOLVENTS; STOMACH;

EVODIA LEPTA; MUS; RUTACEAE;

EID: 84880312884     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.05.030     Document Type: Article

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