Methanol extract of Osbeckia stellata suppresses lipopolysaccharide- and HCl/ethanol-induced inflammatory responses by inhibiting Src/Syk and IRAK1

Journal of Ethnopharmacology

Volumn 143, Issue 3, 2012, Pages 876-883

  Yang, Yanyan ^a   Hyun Moh, Sang ^b   Yu, Tao ^a   Gwang Park, Jae ^a   Hyo Yoon, Deok ^c   Woong Kim, Tae ^c   Hwan Kim, Seong ^d   Lee, Sukchan ^a   Hong, Sungyoul ^a   Youl Cho, Jae ^a  

^a Sungkyunkwan University   (South Korea)

^b Sungkyunkwan University   (South Korea)

^c Kangwon National University   (South Korea)

^d Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

Anti inflammatory effects; Melastomataceae; Nitric oxide; Osbeckia stellata Buch. Ham. ex D. Don; Prostaglandin E2

Indexed keywords

ALCOHOL; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; HYDROCHLORIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; LIPOPOLYSACCHARIDE; METHANOL; NITRIC OXIDE; OSBECKIA STELLATA EXTRACT; PLANT EXTRACT; PROSTAGLANDIN E2; PROTEIN C FOS; PROTEIN KINASE P60; PROTEIN KINASE SYK; RANITIDINE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR REL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GASTRITIS; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PROTEIN EXPRESSION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; ETHANOL; HEK293 CELLS; HUMANS; HYDROCHLORIC ACID; INFLAMMATION; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; MALE; MELASTOMATACEAE; METHANOL; MICE; MICE, INBRED ICR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; PROTEIN-TYROSINE KINASES; SOLVENTS; SRC-FAMILY KINASES;

MELASTOMATACEAE; MUS; OSBECKIA STELLATA;

EID: 84866741840     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.08.015     Document Type: Article

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