ITIH4 and Gpx3 are potential biomarkers for amyotrophic lateral sclerosis

Journal of Neurology

Volumn 260, Issue 7, 2013, Pages 1782-1797

  Tanaka, Hirotaka ^g   Shimazawa, Masamitsu ^g   Takata, Masafumi ^g   Kaneko, Hideo ^a,b   Tsuruma, Kazuhiro ^g   Ikeda, Tsunehiko ^c   Warita, Hitoshi ^d   Aoki, Masashi ^d   Yamada, Mitsunori ^e   Takahashi, Hitoshi ^f   Hozumi, Isao ^g   Minatsu, Hiroshi ^a   Inuzuka, Takashi ^h   Hara, Hideaki ^g  

^a NAGARA MEDICAL CENTER   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c OSAKA MEDICAL COLLEGE   (Japan)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e National Saigata Medical Center   (Japan)

^f NIIGATA UNIVERSITY   (Japan)

^g GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^h GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Amyotrophic lateral sclerosis; Biomarker; Glutathione peroxidase 3; Inter alpha trypsin inhibitor heavy chain H4

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE 3; INTER ALPHA TRYPSIN INHIBITOR; INTER ALPHA TRYPSIN INHIBITOR HEAVY CHAIN H4 PROTEIN; PLASMA PROTEIN; UNCLASSIFIED DRUG;

AGED; ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASYMPTOMATIC DISEASE; CLINICAL ARTICLE; CONTROL; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MALE; MUSCULAR DYSTROPHY; MUTANT; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; SPINAL CORD; TWO DIMENSIONAL ELECTROPHORESIS; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION;

AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BIOLOGICAL MARKERS; BLOOD PROTEINS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; GLUTATHIONE PEROXIDASE; GLYCOPROTEINS; HUMANS; MALE; MIDDLE AGED; PROTEINASE INHIBITORY PROTEINS, SECRETORY; RATS; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC; SUPEROXIDE DISMUTASE;

EID: 84880306585     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-013-6877-3     Document Type: Article

References (41)

1. Aoki M, Kato S, Nagai M, Itoyama Y (2005) Development of a rat model of amyotrophic lateral sclerosis expressing a human SOD1 transgene. Neuropathology 25:365-370
2. Association AP (1994) 4th ed. DSM-IV. Washington D.C
3. Bains JS, Shaw CA (1997) Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death. Brain Res Brain Res Rev 25:335-358
4. Ballabh P, Braun A, Nedergaard M (2004) The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol Dis 16:1-13
5. Barber SC, Mead RJ, Shaw PJ (2006) Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target. Biochim Biophys Acta 1762:1051-1067
6. Barber SC, Shaw PJ (2010) Oxidative stress in ALS: key role in motor neuron injury and therapeutic target. Free Radic Biol Med 48:629-641
7. Boillee S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G, Cleveland DW (2006) Onset and progression in inherited ALS determined by motor neurons and microglia. Science 312:1389-1392
8. Bosco DA, Morfini G, Karabacak NM, Song Y, Gros-Louis F, Pasinelli P, Goolsby H, Fontaine BA, Lemay N, McKenna-Yasek D, Frosch MP, Agar JN, Julien JP, Brady ST, Brown RH Jr (2011) Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nat Neurosci 13:1396-1403
9. Brooks BR, Miller RG, Swash M, Munsat TL (2000) El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Later Scler Other Motor Neuron Disord 1:293-299
10. Choi-Miura NH, Sano Y, Oda E, Nakano Y, Tobe T, Yanagishita T, Taniyama M, Katagiri T, Tomita M (1995) Purification and characterization of a novel glycoprotein which has significant homology to heavy chains of inter-alpha-trypsin inhibitor family from human plasma. J Biochem 117:400-407
11. Cleveland DW, Rothstein JD (2001) From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev Neurosci 2:806-819
12. Dupuis L, de Tapia M, Rene F, Lutz-Bucher B, Gordon JW, Mercken L, Pradier L, Loeffler JP (2000) Differential screening of mutated SOD1 transgenic mice reveals early up-regulation of a fast axonal transport component in spinal cord motor neurons. Neurobiol Dis 7:274-285
13. Ferrante RJ, Browne SE, Shinobu LA, Bowling AC, Baik MJ, MacGarvey U, Kowall NW, Brown RH Jr, Beal MF (1997) Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. J Neurochem 69:2064-2074
14. Fung ET, Yip TT, Lomas L, Wang Z, Yip C, Meng XY, Lin S, Zhang F, Zhang Z, Chan DW, Weinberger SR (2005) Classification of cancer types by measuring variants of host response proteins using SELDI serum assays. Int J Cancer 115:783-789
15. Hirata Y, Matsuda H, Nemoto K, Ohnishi T, Hirao K, Yamashita F, Asada T, Iwabuchi S, Samejima H (2005) Voxel-based morphometry to discriminate early Alzheimer's disease from controls. Neurosci Lett 382:269-274
16. Huang L, Yoneda M, Kimata K (1993) A serum-derived hyaluronan-associated protein (SHAP) is the heavy chain of the inter alpha-trypsin inhibitor. J Biol Chem 268:26725-26730
17. Hughes AJ, Daniel SE, Kilford L, Lees AJ (1992) Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55:181-184
18. Ishida T, Ichihara M, Wang X, Yamamoto K, Kimura J, Majima E, Kiwada H (2006) Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes. J Control Release 112:15-25
19. Ito R, Statland BE (1981) Centrifugal analysis for plasma kallikrein activity, with use of the chromogenic substrate S-2302. Clin Chem 27:586-593
20. Kolarcik C, Bowser R (2006) Plasma and cerebrospinal fluid-based protein biomarkers for motor neuron disease. Mol Diagn Ther 10:281-292
21. 35S] glutathione binding sites in spinal cords from patients with sporadic amyotrophic lateral sclerosis. Neurosci Lett 163:89-92
22. Lubieniecka JM, Streijger F, Lee JH, Stoynov N, Liu J, Mottus R, Pfeifer T, Kwon BK, Coorssen JR, Foster LJ, Grigliatti TA, Tetzlaff W (2011) Biomarkers for severity of spinal cord injury in the cerebrospinal fluid of rats. PLoS ONE 6:e19247
23. Marden JJ, Harraz MM, Williams AJ, Nelson K, Luo M, Paulson H, Engelhardt JF (2007) Redox modifier genes in amyotrophic lateral sclerosis in mice. J Clin Invest 117:2913-2919
24. Matsuda H, Mizumura S, Nagao T, Ota T, Iizuka T, Nemoto K, Takemura N, Arai H, Homma A (2007) Automated discrimination between very early Alzheimer disease and controls using an easy Z-score imaging system for multicenter brain perfusion single-photon emission tomography. AJNR Am J Neuroradiol 28:731-736
25. Mohamed E, Abdul-Rahman PS, Doustjalali SR, Chen Y, Lim BK, Omar SZ, Bustam AZ, Singh VA, Mohd-Taib NA, Yip CH, Hashim OH (2008) Lectin-based electrophoretic analysis of the expression of the 35 kDa inter-alpha-trypsin inhibitor heavy chain H4 fragment in sera of patients with five different malignancies. Electrophoresis 29:2645-2650
26. Moumen R, Nouvelot A, Duval D, Lechevalier B, Viader F (1997) Plasma superoxide dismutase and glutathione peroxidase activity in sporadic amyotrophic lateral sclerosis. J Neurol Sci 151:35-39
27. Nagai M, Aoki M, Miyoshi I, Kato M, Pasinelli P, Kasai N, Brown RH Jr, Itoyama Y (2001) Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease. J Neurosci 21:9246-9254
28. Nishimura H, Kakizaki I, Muta T, Sasaki N, Pu PX, Yamashita T, Nagasawa S (1995) cDNA and deduced amino acid sequence of human PK-120, a plasma kallikrein-sensitive glycoprotein. FEBS Lett 357:207-211
29. Nygren I, Larsson A, Johansson A, Askmark H (2002) VEGF is increased in serum but not in spinal cord from patients with amyotrophic lateral sclerosis. Neuro Report 13:2199-2201
30. 123I-metaiodobenzylguanidine myocardial scintigraphy in Parkinson's disease. J Neurol Neurosurg Psychiatry 67:189-194
31. Pasinelli P, Brown RH (2006) Molecular biology of amyotrophic lateral sclerosis: insights from genetics. Nat Rev Neurosci 7:710-723
32. Pu XP, Iwamoto A, Nishimura H, Nagasawa S (1994) Purification and characterization of a novel substrate for plasma kallikrein (PK-120) in human plasma. Biochim Biophys Acta 1208:338-343
33. Shibata N, Nagai R, Miyata S, Jono T, Horiuchi S, Hirano A, Kato S, Sasaki S, Asayama K, Kobayashi M (2000) Nonoxidative protein glycation is implicated in familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation. Acta Neuropathol 100:275-284
34. Song J, Patel M, Rosenzweig CN, Chan-Li Y, Sokoll LJ, Fung ET, Choi-Miura NH, Goggins M, Chan DW, Zhang Z (2006) Quantification of fragments of human serum inter-alpha-trypsin inhibitor heavy chain 4 by a surface-enhanced laser desorption/ionization-based immunoassay. Clin Chem 52:1045-1053
35. Sun W, Funakoshi H, Nakamura T (2002) Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS. J Neurosci 22:6537-6548
36. Tanaka H, Shimazaki H, Kimura M, Izuta H, Tsuruma K, Shimazawa M, Hara H (2011) Apoptosis-inducing factor and cyclophilin a cotranslocate to the motor neuronal nuclei in amyotrophic lateral sclerosis model mice. CNS Neurosci Ther 17:294-304
37. Villanueva J, Shaffer DR, Philip J, Chaparro CA, Erdjument-Bromage H, Olshen AB, Fleisher M, Lilja H, Brogi E, Boyd J, Sanchez-Carbayo M, Holland EC, Cordon-Cardo C, Scher HI, Tempst P (2006) Differential exoprotease activities confer tumor-specific serum peptidome patterns. J Clin Invest 116:271-284
38. Warita H, Hayashi T, Murakami T, Manabe Y, Abe K (2001) Oxidative damage to mitochondrial DNA in spinal motoneurons of transgenic ALS mice. Brain Res Mol Brain Res 89:147-152
39. Zarkovic K (2003) 4-hydroxynonenal and neurodegenerative diseases. Mol Aspects Med 24:293-303
40. Zhao Z, Lange DJ, Ho L, Bonini S, Shao B, Salton SR, Thomas S, Pasinetti GM (2008) Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis. Int J Med Sci 5:92-99
41. Zhong Z, Deane R, Ali Z, Parisi M, Shapovalov Y, O'Banion MK, Stojanovic K, Sagare A, Boillee S, Cleveland DW, Zlokovic BV (2008) ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. Nat Neurosci 11:420-422