GAPDH binds to active Akt, leading to Bcl-xL increase and escape from caspase-independent cell death

Cell Death and Differentiation

Volumn 20, Issue 8, 2013, Pages 1043-1054

  Jacquin, M A ^a,b   Chiche, J ^a,b   Zunino, B ^a,b,c   Beneteau M ^a,b   Meynet, O ^a,b   Pradelli, L A ^a,b   Marchetti, S ^a,b   Cornille, A ^a,b   Carles, M ^a,c   Ricci, J E ^a,b,c  

^a CENTRE MÉDITERRANÉEN DE MÉDECINE MOLÉCULAIRE C3M   (France)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

^c UNIVERSITY HOSPITAL OF NICE   (France)

Author keywords

Bcl 2 family; Cell death; Glycolysis; Mitochondria; Warburg effect

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; CASPASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOLYTIC ENZYME; PROTEIN BCL XL; PROTEIN KINASE B;

APOPTOSIS; ARTICLE; CANCER CELL DESTRUCTION; CASPASE INDEPENDENT CELL DEATH; CELL DEATH; CELL DIFFERENTIATION; CELL PERMEABILIZATION; CELL PROLIFERATION; CELL PROTECTION; CELL SURVIVAL; CLONOGENESIS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; GLYCOLYSIS; HELA CELL; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSIENT EXPRESSION; TUMOR ESCAPE;

APOPTOSIS; BCL-X PROTEIN; CASPASES; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (NADP+); HEK293 CELLS; HELA CELLS; HUMANS; MITOCHONDRIA; PHOSPHOGLYCERATE KINASE; PHOSPHOPYRUVATE HYDRATASE; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; UP-REGULATION;

EID: 84880292287     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.32     Document Type: Article

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