Enhancement of CD154/IL4 proliferation by the T follicular helper (Tfh) cytokine, IL21 and increased numbers of circulating cells resembling Tfh cells in chronic lymphocytic leukaemia

British Journal of Haematology

Volumn 162, Issue 3, 2013, Pages 360-370

  Ahearne, Matthew J ^a   Willimott, Shaun ^a   Piñon, Lucia ^a   Kennedy, D Benjamin ^b   Miall, Fiona ^b   Dyer, Martin J S ^b   Wagner, Simon D ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b LEICESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

CD154; Chronic lymphocytic leukaemia; IL21; Microenvironment; T follicular helper

Indexed keywords

CD40 LIGAND; CELL PROTEIN; INTERLEUKIN 21; INTERLEUKIN 4; PD1 PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER RESISTANCE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL RENEWAL; CELL SURFACE; CHRONIC LYMPHATIC LEUKEMIA; CIRCULATING TUMOR CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENE MUTATION; HELPER CELL; HUMAN; HUMAN CELL; IGHV GENE; LEUKEMIA CELL; LYMPH NODE; LYMPHOCYTE COUNT; MALE; MUTATOR GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIDE POPULATION CELL; T FOLLICULAR HELPER CELL; T LYMPHOCYTE SUBPOPULATION; TUMOR MICROENVIRONMENT;

CD154; CHRONIC LYMPHOCYTIC LEUKAEMIA; IL21; MICROENVIRONMENT; T FOLLICULAR HELPER;

APOPTOSIS; CD40 LIGAND; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOKINES; FEMALE; HUMANS; INTERLEUKIN-4; INTERLEUKINS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; LYMPH NODES; LYMPHOCYTE COUNT; MALE; PROGRAMMED CELL DEATH 1 RECEPTOR; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER; TUMOR CELLS, CULTURED; TUMOR MICROENVIRONMENT;

EID: 84880262286     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.12401     Document Type: Article

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