Reactions of the flavin mononucleotide in complex I: A combined mechanism describes NADH oxidation coupled to the reduction of APAD+, ferricyanide, or molecular oxygen

Biochemistry

Volumn 48, Issue 50, 2009, Pages 12005-12013

  Birrell, James A ^a   Yakovlev, Gregory ^a   Hirst, Judy ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ADP-RIBOSE; COMBINED MECHANISMS; COMBINED MODELING; DISSOCIATION CONSTANT; ELECTRON ACCEPTOR; ENZYME COMPLEXES; FLAVIN MONONUCLEOTIDES; FLAVIN OXIDATION; INNER MEMBRANES; MICHAELIS-MENTEN EQUATIONS; NADH OXIDATION; NON-ENERGY; OXIDOREDUCTASES; PROTON-MOTIVE FORCES; REACTIVE OXYGEN SPECIES; RESPIRATORY CHAIN ENZYMES; SECOND-ORDER RATE CONSTANTS; SUPEROXIDES; THERMODYNAMIC INFORMATION; TRANSDUCING; TRANSHYDROGENATION; UBIQUINONE;

AMIDES; DISSOCIATION; ELECTRONS; ENZYMES; HYDROPHILICITY; NUCLEIC ACIDS; NUCLEOTIDES; OXIDATION; RATE CONSTANTS; REACTION KINETICS;

MOLECULAR OXYGEN;

FERRICYANIDE; FLAVINE MONONUCLEOTIDE; NUCLEOTIDE; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ARTICLE; COMPETITIVE INHIBITION; ENZYME KINETICS; MICHAELIS MENTEN KINETICS; NONHUMAN; OXIDATION; OXIDATION KINETICS; PRIORITY JOURNAL; THERMODYNAMICS;

ANIMALS; BINDING, COMPETITIVE; CATALYSIS; CATTLE; ELECTRON TRANSPORT COMPLEX I; FERRICYANIDES; FLAVIN MONONUCLEOTIDE; KINETICS; NAD; OXIDATION-REDUCTION; OXYGEN; PROTEIN BINDING; RUTHENIUM COMPOUNDS;

EID: 72449148626     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi901706w     Document Type: Article

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