A compact, in vivo screen of all 6-mers reveals drivers of tissue-specific expression and guides synthetic regulatory element design

Genome Biology

Volumn 14, Issue 7, 2013, Pages

  Smith, Robin P ^a   Riesenfeld, Samantha J ^a   Holloway, Alisha K ^a   Li, Qiang ^a,c   Murphy, Karl K ^a   Feliciano, Natalie M ^a   Orecchia, Lorenzo ^a   Oksenberg, Nir ^a   Pollard, Katherine S ^a,b   Ahituv, Nadav ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c CHILDREN S HOSPITAL OF FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; GREEN FLUORESCENT PROTEIN; OLIGOMER; TRANSCRIPTION FACTOR; OLIGONUCLEOTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASE PAIRING; DNA LIBRARY; EMBRYO; EPIDERMIS; FOREBRAIN; GENE CONSTRUCT; GENE EXPRESSION; GENETIC ALGORITHM; GENETIC SCREENING; IN VIVO STUDY; LATERAL LINE SYSTEM; NONHUMAN; NOTOCHORD; PROMOTER REGION; PROTEIN MOTIF; REGULATORY DNA SEQUENCE; SPINAL CORD; TISSUE SPECIFICITY; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; ANTIBODY SPECIFICITY; DISSECTION; EMBRYOLOGY; ENHANCER REGION; GENE EXPRESSION REGULATION; GENE ONTOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE MOTIF; NUCLEOTIDE SEQUENCE; PROCEDURES; REGULATORY SEQUENCE; SYNTHETIC BIOLOGY; ALGORITHM; CONTROLLED STUDY; PROTEIN EXPRESSION; SEQUENCE ANALYSIS;

DANIO RERIO; VERTEBRATA;

ANIMALS; BASE SEQUENCE; DISSECTION; EMBRYO, NONMAMMALIAN; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE ONTOLOGY; MOLECULAR SEQUENCE DATA; NUCLEOTIDE MOTIFS; OLIGONUCLEOTIDES; ORGAN SPECIFICITY; REGULATORY SEQUENCES, NUCLEIC ACID; SYNTHETIC BIOLOGY; ZEBRAFISH;

EID: 84880181407     PISSN: None     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/gb-2013-14-7-r72     Document Type: Article

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