Inhibitory effect of carbazolequinone derivatives on lipopolysaccharide and interferon-γ-induced nitric oxide production in mouse macrophage RAW264.7 cells

Journal of Pharmacy and Pharmacology

Volumn 65, Issue 8, 2013, Pages 1204-1213

  Murata, Tomiyasu ^a   Kohno, Susumu ^c   Ito, Chihiro ^a   Itoigawa, Masataka ^b   Sugiura, Ayumi ^a   Hikita, Kiyomi ^a   Kaneda, Norio ^a  

^a MEIJO UNIVERSITY   (Japan)

^b TOKAI GAKUEN UNIVERSITY   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

Author keywords

carbazolequinone; COX 2; iNOS; nitric oxide; prostaglandin E2; tsAM5NE cells

Indexed keywords

6 CHLORO 2 METHYLCARBAZOLE 1,4 QUINONE; 6 METHOXY 2 METHYLCARBAZOLE 1,4 QUINONE; 7 METHOXY 2 METHYLCARBAZOLE 1,4 QUINONE; CARBOQUONE; CYCLOOXYGENASE 2; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; LUCIFERASE; NITRIC OXIDE; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL FRACTIONATION; DOWN REGULATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; MACROPHAGE; MOUSE; NERVE CELL DIFFERENTIATION; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRUCTURE ANALYSIS; SUPERNATANT;

CARBAZOLEQUINONE; COX-2; INOS; NITRIC OXIDE; PROSTAGLANDIN E2; TSAM5NE CELLS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CARBAZOLES; CELL CULTURE TECHNIQUES; CELL LINE; CYCLOOXYGENASE 2; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MOLECULAR STRUCTURE; MURRAYA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; QUINONES;

EID: 84880135500     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12087     Document Type: Article

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