Doxycycline prevents matrix remodeling and contraction by trichiasis-derived conjunctival fibroblasts

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 7, 2013, Pages 4675-4682

  Li, He ^a   Ezra, Daniel G ^a,b   Burton, Matthew J ^b,c   Bailly, Maryse ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Contraction; Doxycycline; MMPs; Trichiasis

Indexed keywords

COLLAGEN GEL; DOXYCYCLINE; GELATINASE B; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; MATRILYSIN;

ARTICLE; CELL SURVIVAL; CONFOCAL MICROSCOPY; CONJUNCTIVA; CONJUNCTIVAL BIOPSY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; FIBROBLAST; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; HUMAN TISSUE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SCAR FORMATION; TRICHIASIS;

CONTRACTION; DOXYCYCLINE; MMPS; TRICHIASIS;

CELL-MATRIX JUNCTIONS; CELLS, CULTURED; COLLAGEN; CONJUNCTIVA; DOXYCYCLINE; ENZYME INHIBITORS; FIBROBLASTS; HUMANS; MATRIX METALLOPROTEINASE 1; MODELS, BIOLOGICAL; TRACHOMA; TRICHIASIS;

EID: 84880116664     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.13-11787     Document Type: Article

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