Effects of doxycycline on production of growth factors and matrix metalloproteinases in pulmonary fibrosis

Respiration

Volumn 81, Issue 5, 2011, Pages 420-430

  Fujita, Hanako ^a   Sakamoto, Noriho ^a   Ishimatsu, Yuji ^a   Kakugawa, Tomoyuki ^a   Hara, Shintaro ^a   Hara, Atsuko ^a   Amenomori, Misato ^a   Ishimoto, Hiroshi ^b   Nagata, Towako ^a   Mukae, Hiroshi ^b   Kohno, Shigeru ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Alveolar epithelial cells; Connective tissue growth factor; Epithelial mesenchymal transition; Fibroblast; Smad

Indexed keywords

BLEOMYCIN; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; DOXYCYCLINE; GELATINASE A; GELATINASE B; GROWTH FACTOR; HYDROXYPROLINE; MATRIX METALLOPROTEINASE; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR AA; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROSING ALVEOLITIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS EPITHELIUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-BACTERIAL AGENTS; BLOTTING, WESTERN; CELL LINE; COLLAGEN TYPE I; CONNECTIVE TISSUE GROWTH FACTOR; DOXYCYCLINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED ICR; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PULMONARY ALVEOLI; PULMONARY FIBROSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 79955086683     PISSN: 00257931     EISSN: None     Source Type: Journal    
DOI: 10.1159/000324080     Document Type: Article

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