Rac1 inhibition prevents tissue contraction and MMP mediated matrix remodeling in the conjunctiva

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 8, 2012, Pages 4682-4691

  Tovell, Victoria E ^a   Chau, Chi Y ^a   Khaw, Peng T ^a   Bailly, Maryse ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL] AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; COLLAGEN; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; RAC1 PROTEIN; SIMVASTATIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; 4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; AMINOQUINOLINE DERIVATIVE; ENZYME INHIBITOR; MESSENGER RNA; PYRIMIDINE DERIVATIVE; RAC1 PROTEIN, HUMAN;

ARTICLE; CONFOCAL MICROSCOPY; CONJUNCTIVA; CONTROLLED STUDY; CYTOTOXICITY; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TENON CAPSULE; TISSUE CONTRACTION; TISSUE REGENERATION; WESTERN BLOTTING; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; EXTRACELLULAR MATRIX; METABOLISM;

AMINOQUINOLINES; BLOTTING, WESTERN; CELLS, CULTURED; COLLAGEN; CONJUNCTIVA; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; FIBROBLASTS; HUMANS; MATRIX METALLOPROTEINASES; PYRIMIDINES; RAC1 GTP-BINDING PROTEIN; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84866522934     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-8577     Document Type: Article

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