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Volumn 288, Issue 25, 2013, Pages 18381-18391

Sphingosine-1-phosphate phosphatase 1 regulates keratinocyte differentiation and epidermal homeostasis

Author keywords

[No Author keywords available]

Indexed keywords

DEPHOSPHORYLATES; EPIDERMAL DEFECTS; EPIDERMAL HOMEOSTASIS; IN-VIVO; KERATINOCYTE DIFFERENTIATION; KERATINOCYTES;

EID: 84880059996     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.478420     Document Type: Article
Times cited : (42)

References (63)
  • 1
    • 52949108813 scopus 로고    scopus 로고
    • The alliance of sphingosine 1-phosphate and its receptors in immunity
    • Rivera, J., Proia, R. L., and Olivera, A. (2008) The alliance of sphingosine 1-phosphate and its receptors in immunity. Nat. Rev. Immunol. 8, 753-763
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 753-763
    • Rivera, J.1    Proia, R.L.2    Olivera, A.3
  • 2
    • 77953790503 scopus 로고    scopus 로고
    • An update on sphingosine 1-phosphate and other sphingolipid mediators
    • Fyrst, H., and Saba, J. D. (2010) An update on sphingosine 1-phosphate and other sphingolipid mediators. Nat. Chem. Biol. 6, 489-497
    • (2010) Nat. Chem. Biol. , vol.6 , pp. 489-497
    • Fyrst, H.1    Saba, J.D.2
  • 4
    • 38549152194 scopus 로고    scopus 로고
    • Principles of bioactive lipid signalling: Lessons from sphingolipids
    • DOI 10.1038/nrm2329, PII NRM2329
    • Hannun, Y. A., and Obeid, L. M. (2008) Principles of bioactive lipid signalling: Lessons from sphingolipids. Nat. Rev. Mol. Cell Biol. 9, 139-150 (Pubitemid 351158911)
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.2 , pp. 139-150
    • Hannun, Y.A.1    Obeid, L.M.2
  • 5
    • 0038218405 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate: An enigmatic signalling lipid
    • DOI 10.1038/nrm1103
    • Spiegel, S., and Milstien, S. (2003) Sphingosine 1-phosphate: An enigmatic signalling lipid. Nat. Rev. Mol. Cell Biol. 4, 397-407 (Pubitemid 36565571)
    • (2003) Nature Reviews Molecular Cell Biology , vol.4 , Issue.5 , pp. 397-407
    • Spiegel, S.1    Milstien, S.2
  • 6
    • 16644383300 scopus 로고    scopus 로고
    • Lysophospholipid receptor-dependent and -independent calcium signaling
    • DOI 10.1002/jcb.20107
    • Meyer Zu Heringdorf, D. (2004) Lysophospholipid receptor-dependent and-independent calcium signaling. J. Cell Biochem. 92, 937-948 (Pubitemid 44264243)
    • (2004) Journal of Cellular Biochemistry , vol.92 , Issue.5 , pp. 937-948
    • Meyer Zu Heringdorf, D.1
  • 10
    • 80054079107 scopus 로고    scopus 로고
    • Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics
    • Merrill, A. H., Jr. (2011) Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics. Chem. Rev. 111, 6387-6422
    • (2011) Chem. Rev. , vol.111 , pp. 6387-6422
    • Merrill Jr., A.H.1
  • 11
    • 28844452498 scopus 로고    scopus 로고
    • Lipid phosphate phosphatases and lipid phosphate signalling
    • DOI 10.1042/BST20051370
    • Pyne, S., Long, J. S., Ktistakis, N. T., and Pyne, N. J. (2005) Lipid phosphate phosphatases and lipid phosphate signalling. Biochem. Soc. Trans. 33, 1370-1374 (Pubitemid 41779690)
    • (2005) Biochemical Society Transactions , vol.33 , Issue.6 , pp. 1370-1374
    • Pyne, S.1    Long, J.S.2    Ktistakis, N.T.3    Pyne, N.J.4
  • 14
    • 66349139391 scopus 로고    scopus 로고
    • Lipid phosphate phosphatases and signaling
    • Brindley, D. N., and Pilquil, C. (2009) Lipid phosphate phosphatases and signaling. J. Lipid Res. 50, S225-S230
    • (2009) J. Lipid Res. , vol.50
    • Brindley, D.N.1    Pilquil, C.2
  • 16
    • 0030712997 scopus 로고    scopus 로고
    • Identification and characterization of Saccharomyces cerevisiae dihydrosphingosine-1-phosphate phosphatase
    • DOI 10.1074/jbc.272.45.28690
    • Mao, C., Wadleigh, M., Jenkins, G. M., Hannun, Y. A., and Obeid, L. M. (1997) Identification and characterization of Saccharomyces cerevisiae dihydrosphingosine-1-phosphate phosphatase. J. Biol. Chem. 272, 28690-28694 (Pubitemid 27517825)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.45 , pp. 28690-28694
    • Mao, C.1    Wadleigh, M.2    Jenkins, G.M.3    Hannun, Y.A.4    Obeid, L.M.5
  • 19
    • 0037428384 scopus 로고    scopus 로고
    • Identification and characterization of a novel human sphingosine-1- phosphate phosphohydrolase, hSPP2
    • DOI 10.1074/jbc.M209514200
    • Ogawa, C., Kihara, A., Gokoh, M., and Igarashi, Y. (2003) Identification and characterization of a novel human sphingosine-1-phosphate phosphohydrolase, hsp26. J. Biol. Chem. 278, 1268-1272 (Pubitemid 36790810)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.2 , pp. 1268-1272
    • Ogawa, C.1    Kihara, A.2    Gokoh, M.3    Igarashi, Y.4
  • 22
    • 84455172960 scopus 로고    scopus 로고
    • Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage
    • Lépine, S., Allegood, J. C., Edmonds, Y., Milstien, S., and Spiegel, S. (2011) Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage. J. Biol. Chem. 286, 44380-44390
    • (2011) J. Biol. Chem. , vol.286 , pp. 44380-44390
    • Lépine, S.1    Allegood, J.C.2    Edmonds, Y.3    Milstien, S.4    Spiegel, S.5
  • 23
    • 78651265495 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy
    • Lépine, S., Allegood, J. C., Park, M., Dent, P., Milstien, S., and Spiegel, S. (2011) Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy. Cell Death Differ. 18, 350-361
    • (2011) Cell Death Differ. , vol.18 , pp. 350-361
    • Lépine, S.1    Allegood, J.C.2    Park, M.3    Dent, P.4    Milstien, S.5    Spiegel, S.6
  • 27
    • 66349097798 scopus 로고    scopus 로고
    • The outer frontier: The importance of lipid metabolism in the skin
    • Feingold, K. R. (2009) The outer frontier: The importance of lipid metabolism in the skin. J. Lipid Res. 50, S417-S422
    • (2009) J. Lipid Res. , vol.50
    • Feingold, K.R.1
  • 28
    • 33749049791 scopus 로고    scopus 로고
    • Epidermal sphingolipids: Metabolism, function, and roles in skin disorders
    • DOI 10.1016/j.febslet.2006.08.039, PII S0014579306010155
    • Holleran, W. M., Takagi, Y., and Uchida, Y. (2006) Epidermal sphingolipids: Metabolism, function, and roles in skin disorders. FEBS Lett. 580, 5456-5466 (Pubitemid 44465907)
    • (2006) FEBS Letters , vol.580 , Issue.23 , pp. 5456-5466
    • Holleran, W.M.1    Takagi, Y.2    Uchida, Y.3
  • 29
    • 0026693975 scopus 로고
    • Lipids and the epidermal water barrier: Metabolism, regulation, and pathophysiology
    • Elias, P. M., and Feingold, K. R. (1992) Lipids and the epidermal water barrier: Metabolism, regulation, and pathophysiology. Semin. Dermatol. 11, 176-182
    • (1992) Semin. Dermatol. , vol.11 , pp. 176-182
    • Elias, P.M.1    Feingold, K.R.2
  • 30
    • 0034939951 scopus 로고    scopus 로고
    • Sphingolipid activator proteins: Proteins with complex functions in lipid degradation and skin biogenesis
    • Schuette, C. G., Pierstorff, B., Huettler, S., and Sandhoff, K. (2001) Sphingolipid activator proteins: Proteins with complex functions in lipid degradation and skin biogenesis. Glycobiology 11, 81R-90R (Pubitemid 32655236)
    • (2001) Glycobiology , vol.11 , Issue.6
    • Schuette, C.G.1    Pierstorff, B.2    Huettler, S.3    Sandhoff, K.4
  • 32
    • 0037378439 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate and its potentially paradoxical effects on critical parameters of cutaneous wound healing
    • DOI 10.1046/j.1523-1747.2003.12096.x
    • Vogler, R., Sauer, B., Kim, D. S., Schäfer-Korting, M., and Kleuser, B. (2003) Sphingosine 1-phosphate and its potentially paradoxical effects on critical parameters of cutaneous wound healing. J. Invest. Dermatol. 120, 693-700 (Pubitemid 36344015)
    • (2003) Journal of Investigative Dermatology , vol.120 , Issue.4 , pp. 693-700
    • Vogler, R.1    Sauer, B.2    Kim, D.-S.3    Schafer-Korting, M.4    Kleuser, B.5
  • 33
    • 45449120119 scopus 로고    scopus 로고
    • K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling
    • Hong, J. H., Youm, J. K., Kwon, M. J., Park, B. D., Lee, Y. M., Lee, S. I., Shin, D. M., and Lee, S. H. (2008) K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling. J. Invest. Dermatol. 128, 2166-2178
    • (2008) J. Invest. Dermatol. , vol.128 , pp. 2166-2178
    • Hong, J.H.1    Youm, J.K.2    Kwon, M.J.3    Park, B.D.4    Lee, Y.M.5    Lee, S.I.6    Shin, D.M.7    Lee, S.H.8
  • 34
    • 84858276574 scopus 로고    scopus 로고
    • SERCA2-controlled Ca2+-dependent keratinocyte adhesion and differentiation is mediated via the sphingolipid pathway: A therapeutic target for Darier's disease
    • Celli, A., Mackenzie, D. S., Zhai, Y., Tu, C. L., Bikle, D. D., Holleran, W. M., Uchida, Y., and Mauro, T. M. (2012) SERCA2-controlled Ca2+-dependent keratinocyte adhesion and differentiation is mediated via the sphingolipid pathway: A therapeutic target for Darier's disease. J. Invest. Dermatol. 132, 1188-1195
    • (2012) J. Invest. Dermatol. , vol.132 , pp. 1188-1195
    • Celli, A.1    Mackenzie, D.S.2    Zhai, Y.3    Tu, C.L.4    Bikle, D.D.5    Holleran, W.M.6    Uchida, Y.7    Mauro, T.M.8
  • 35
    • 0242384063 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate inhibits human keratinocyte proliferation via Akt/protein kinase B inactivation
    • DOI 10.1016/S0898-6568(03)00114-1
    • Kim, D. S., Kim, S. Y., Kleuser, B., Schäfer-Korting, M., Kim, K. H., and Park, K. C. (2004) Sphingosine 1-phosphate inhibits human keratinocyte proliferation via Akt/protein kinase B inactivation. Cell. Signal. 16, 89-95 (Pubitemid 37357195)
    • (2004) Cellular Signalling , vol.16 , Issue.1 , pp. 89-95
    • Kim, D.-S.1    Kim, S.-Y.2    Kleuser, B.3    Schafer-Korting, M.4    Kim, K.-H.5    Park, K.-C.6
  • 36
    • 84868545646 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate protects primary human keratinocytes from apoptosis via nitric oxide formation through the receptor subtype S1P(3
    • Schmitz, E. I., Potteck, H., Schuppel, M., Manggau, M., Wahydin, E., and Kleuser, B. (2012) Sphingosine 1-phosphate protects primary human keratinocytes from apoptosis via nitric oxide formation through the receptor subtype S1P(3). Mol. Cell. Biochem. 371, 165-176
    • (2012) Mol. Cell. Biochem. , vol.371 , pp. 165-176
    • Schmitz, E.I.1    Potteck, H.2    Schuppel, M.3    Manggau, M.4    Wahydin, E.5    Kleuser, B.6
  • 39
    • 43149084824 scopus 로고    scopus 로고
    • Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice
    • DOI 10.1038/nprot.2008.50, PII NPROT.2008.50
    • Lichti, U., Anders, J., and Yuspa, S. H. (2008) Isolation and short-term culture of primary keratinocytes, hair follicle populations, and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice. Nat. Protoc. 3, 799-810 (Pubitemid 351639024)
    • (2008) Nature Protocols , vol.3 , Issue.5 , pp. 799-810
    • Lichti, U.1    Anders, J.2    Yuspa, S.H.3
  • 42
    • 33746271951 scopus 로고    scopus 로고
    • Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry
    • DOI 10.1016/j.ymeth.2006.05.004, PII S1046202306000727
    • Bielawski, J., Szulc, Z. M., Hannun, Y. A., and Bielawska, A. (2006) Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. Methods 39, 82-91 (Pubitemid 44107706)
    • (2006) Methods , vol.39 , Issue.2 , pp. 82-91
    • Bielawski, J.1    Szulc, Z.M.2    Hannun, Y.A.3    Bielawska, A.4
  • 43
    • 34047261628 scopus 로고    scopus 로고
    • Increase of ceramide monohexoside and dipalmitoyl glycerophospholipids in the brain of Zellweger syndrome
    • DOI 10.1016/j.neulet.2007.01.083, PII S0304394007001310
    • Saitoh, M., Sakakihara, Y., Mizuguchi, M., Itoh, M., Takashima, S., Iwamori, M., Kamoshita, S., and Igarashi, T. (2007) Increase of ceramide monohexoside and dipalmitoylglycerophospholipids in the brain of Zellweger syndrome. Neurosci. Lett. 417, 165-170 (Pubitemid 46551352)
    • (2007) Neuroscience Letters , vol.417 , Issue.2 , pp. 165-170
    • Saitoh, M.1    Sakakihara, Y.2    Mizuguchi, M.3    Itoh, M.4    Takashima, S.5    Iwamori, M.6    Kamoshita, S.7    Igarashi, T.8
  • 45
    • 0031865846 scopus 로고    scopus 로고
    • Patterned acquisition of skin barrier function during development
    • Hardman, M. J., Sisi, P., Banbury, D. N., and Byrne, C. (1998) Patterned acquisition of skin barrier function during development. Development 125, 1541-1552 (Pubitemid 28239364)
    • (1998) Development , vol.125 , Issue.8 , pp. 1541-1552
    • Hardman, M.J.1    Sisi, P.2    Banbury, D.N.3    Byrne, C.4
  • 46
    • 0021223740 scopus 로고
    • Monoclonal antibody analysis of keratin expression in epidermal diseases: A 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes
    • Weiss, R. A., Eichner, R., and Sun, T. T. (1984) Monoclonal antibody analysis of keratin expression in epidermal diseases: A 48-and 56-kilodalton keratin as molecular markers for hyperproliferative keratinocytes. J. Cell Biol. 98, 1397-1406 (Pubitemid 14128924)
    • (1984) Journal of Cell Biology , vol.98 , Issue.4 , pp. 1397-1406
    • Weiss, R.A.1    Eichner, R.2    Sun, T.T.3
  • 47
    • 0023181424 scopus 로고
    • Changes in keratinocyte maturation during wound healing
    • Mansbridge, J. N., and Knapp, A. M. (1987) Changes in keratinocyte maturation during wound healing. J. Invest. Dermatol. 89, 253-263 (Pubitemid 17135369)
    • (1987) Journal of Investigative Dermatology , vol.89 , Issue.3 , pp. 253-263
    • Mansbridge, J.N.1    Knappe, A.M.2
  • 48
    • 0023683885 scopus 로고
    • Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation
    • Stoler, A., Kopan, R., Duvic, M., and Fuchs, E. (1988) Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation. J. Cell Biol. 107, 427-446
    • (1988) J. Cell Biol. , vol.107 , pp. 427-446
    • Stoler, A.1    Kopan, R.2    Duvic, M.3    Fuchs, E.4
  • 49
    • 0032559341 scopus 로고    scopus 로고
    • A structural scaffolding of intermediate filaments in health and disease
    • DOI 10.1126/science.279.5350.514
    • Fuchs, E., and Cleveland, D. W. (1998) A structural scaffolding of intermediate filaments in health and disease. Science 279, 514-519 (Pubitemid 28067272)
    • (1998) Science , vol.279 , Issue.5350 , pp. 514-519
    • Fuchs, E.1    Cleveland, D.W.2
  • 50
    • 0018866880 scopus 로고
    • Changes in keratin gene expression during terminal differentiation of the keratinocyte
    • Fuchs, E., and Green, H. (1980) Changes in keratin gene expression during terminal differentiation of the keratinocyte. Cell 19, 1033-1042 (Pubitemid 10155237)
    • (1980) Cell , vol.19 , Issue.4 , pp. 1033-1042
    • Fuchs, E.1    Green, H.2
  • 51
    • 17144371855 scopus 로고    scopus 로고
    • The cornified envelope: A model of cell death in the skin
    • DOI 10.1038/nrm1619
    • Candi, E., Schmidt, R., and Melino, G. (2005) The cornified envelope: A model of cell death in the skin. Nat. Rev. Mol. Cell Biol. 6, 328-340 (Pubitemid 40516899)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.4 , pp. 328-340
    • Candi, E.1    Schmidt, R.2    Melino, G.3
  • 52
    • 0034733910 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate: Signaling inside and out
    • DOI 10.1016/S0014-5793(00)01670-7, PII S0014579300016707
    • Spiegel, S., and Milstien, S. (2000) Sphingosine 1-phosphate: Signaling inside and out. FEBS Lett. 476, 55-57 (Pubitemid 30394650)
    • (2000) FEBS Letters , vol.476 , Issue.1-2 , pp. 55-57
    • Spiegel, S.1    Milstien, S.2
  • 54
    • 0021796108 scopus 로고
    • Ionic calcium reservoirs in mammalian epidermis: Ultrastructural localization by ion-capture cytochemistry
    • Menon, G. K., Grayson, S., and Elias, P. M. (1985) Ionic calcium reservoirs in mammalian epidermis: Ultrastructural localization by ion-capture cytochemistry. J. Invest. Dermatol. 84, 508-512 (Pubitemid 15053207)
    • (1985) Journal of Investigative Dermatology , vol.84 , Issue.6 , pp. 508-512
    • Menon, G.K.1    Grayson, S.2    Elias, P.M.3
  • 56
    • 84868539338 scopus 로고    scopus 로고
    • Shaping the landscape Metabolic regulation of S1P gradients
    • Olivera, A., Allende, M. L., and Proia, R. L. (2013) Shaping the landscape: Metabolic regulation of S1P gradients. Biochim. Biophys. Acta 183, 193-202
    • (2013) Biochim Biophys Acta , vol.183 , pp. 193-202
    • Olivera, A.1    Allende, M.L.2    Proia, R.L.3
  • 57
    • 79953190058 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking
    • Allende, M. L., Bektas, M., Lee, B. G., Bonifacino, E., Kang, J., Tuymetova, G., Chen, W., Saba, J. D., and Proia, R. L. (2011) Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking. J. Biol. Chem. 286, 7348-7358
    • (2011) J. Biol. Chem. , vol.286 , pp. 7348-7358
    • Allende, M.L.1    Bektas, M.2    Lee, B.G.3    Bonifacino, E.4    Kang, J.5    Tuymetova, G.6    Chen, W.7    Saba, J.D.8    Proia, R.L.9
  • 58
    • 0025955624 scopus 로고
    • Sphingolipids are required for mammalian epidermal barrier function. Inhibition of sphingolipid synthesis delays barrier recovery after acute perturbation
    • Holleran, W. M., Man, M. Q., Gao, W. N., Menon, G. K., Elias, P. M., and Feingold, K. R. (1991) Sphingolipids are required for mammalian epidermal barrier function. Inhibition of sphingolipid synthesis delays barrier recovery after acute perturbation. J. Clin. Invest. 88, 1338-1345
    • (1991) J. Clin. Invest. , vol.88 , pp. 1338-1345
    • Holleran, W.M.1    Man, M.Q.2    Gao, W.N.3    Menon, G.K.4    Elias, P.M.5    Feingold, K.R.6
  • 59
    • 0026265525 scopus 로고
    • Structural and lipid biochemical correlates of the epidermal permeability barrier
    • Elias, P. M., and Menon, G. K. (1991) Structural and lipid biochemical correlates of the epidermal permeability barrier. Adv. Lipid Res. 24, 1-26
    • (1991) Adv. Lipid Res. , vol.24 , pp. 1-26
    • Elias, P.M.1    Menon, G.K.2
  • 60
    • 45449109994 scopus 로고    scopus 로고
    • ω-O-Acylceramide, a lipid essential for mammalian survival
    • Uchida, Y., and Holleran, W. M. (2008) ω-O-Acylceramide, a lipid essential for mammalian survival. J. Dermatol. Sci. 51, 77-87
    • (2008) J. Dermatol. Sci. , vol.51 , pp. 77-87
    • Uchida, Y.1    Holleran, W.M.2
  • 61
    • 0028985962 scopus 로고
    • Chelation of intracellular Ca2+ inhibits murine keratinocyte differentiation in vitro
    • Li, L., Tucker, R. W., Hennings, H., and Yuspa, S. H. (1995) Chelation of intracellular Ca2+ inhibits murine keratinocyte differentiation in vitro. J. Cell Physiol. 163, 105-114
    • (1995) J. Cell Physiol. , vol.163 , pp. 105-114
    • Li, L.1    Tucker, R.W.2    Hennings, H.3    Yuspa, S.H.4
  • 62
    • 38149088114 scopus 로고    scopus 로고
    • Up-regulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes
    • Sun, W., Xu, R., Hu, W., Jin, J., Crellin, H. A., Bielawski, J., Szulc, Z. M., Thiers, B. H., Obeid, L. M., and Mao, C. (2008) Up-regulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes. J. Invest. Dermatol. 128, 389-397
    • (2008) J. Invest. Dermatol. , vol.128 , pp. 389-397
    • Sun, W.1    Xu, R.2    Hu, W.3    Jin, J.4    Crellin, H.A.5    Bielawski, J.6    Szulc, Z.M.7    Thiers, B.H.8    Obeid, L.M.9    Mao, C.10
  • 63
    • 0031465070 scopus 로고    scopus 로고
    • Permeability barrier disruption coordinately regulates mRNA levels for key enzymes of cholesterol, fatty acid, and ceramide synthesis in the epidermis
    • Harris, I. R., Farrell, A. M., Grunfeld, C., Holleran, W. M., Elias, P. M., and Feingold, K. R. (1997) Permeability barrier disruption coordinately regulates mRNA levels for key enzymes of cholesterol, fatty acid, and ceramide synthesis in the epidermis. J. Invest. Dermatol. 109, 783-787 (Pubitemid 28053529)
    • (1997) Journal of Investigative Dermatology , vol.109 , Issue.6 , pp. 783-787
    • Harris, I.R.1    Farrell, A.M.2    Grunfeld, C.3    Holleran, W.M.4    Elias, P.M.5    Feingold, K.R.6


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