Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG- 1

Molecular Biology of the Cell

Volumn 10, Issue 4, 1999, Pages 1179-1190

  Liu, Catherine H ^a   Thangada, Shobha ^a   Lee, Menq Jer ^a   Van Brooklyn, James R ^b   Spiegel, Sarah ^b   Hla, Timothy ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; MEMBRANE RECEPTOR; SPHINGOSINE 1 PHOSPHATE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELLULAR DISTRIBUTION; ENDOSOME; HUMAN; HUMAN CELL; INTERNALIZATION; INTRACELLULAR TRANSPORT; LIGAND BINDING; PRIORITY JOURNAL; RECEPTOR BINDING;

EID: 0032938741     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.10.4.1179     Document Type: Article

References (44)

1. An, S., Bleu, T., Huang, W., Hallmark, O.G., Coughlin, S.R., and Goetzl, E.J. (1997). Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids. FEBS Lett. 417, 279-282.
2. Barak, L.S., Ferguson, S.S.G., Zhang, J., Martenson, C., Meyer, T., and Caron, M.G. (1997). Internal trafficking and surface mobility of a functionally intact β2-adrenergic receptor-green fluorescent protein conjugate. Mol. Pharmacol. 51, 177-184.
3. Bornfeldt, K.E., et al. (1995). Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction. J. Cell Biol. 130, 193-206.
4. Buehrer, B.M., and Bell, R.M. (1993). Sphingosine kinase: properties and cellular functions. Adv. Lipid Res. 26, 59-67.
5. Carman, C.V., and Benovic, J.L. (1998). G-protein-coupled receptors: turn-ons and turn-offs. Curr. Opin. Neurobiol. 8, 335-344.
6. Choi, O.H., Kim, J.H., and Kinet, J.P. (1996). Calcium mobilization via sphingosine kinase in signaling by the Fc ∈ RI antigen receptor. Nature 380, 634-636.
7. Cuvillier, O., Pirianov, G., Kleuser, B., Vanek, P.G., Coso, O.A., Gutkind, S., and Spiegel, S. (1996). Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature 381, 800-803.
8. Daaka, Y., Luttrell, L.M., Ahn, S., Della Rocca, G.J., Ferguson, S.S., Caron, M.G., and Lefkowitz, R.J. (1998). Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. J. Biol. Chem. 273, 685-688.
9. Edsall, L.C., Pirianov, G.G., and Spiegel, S. (1997). Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation. J. Neurosci. 17, 6952-6960.
10. Farkas, D.L., Wei, M.D., Febbroriello, P., Carson, J.H., and Loew, L.M. (1989). Simultaneous imaging of cell and mitochondrial membrane potentials. Biophys. J. 56, 1053-1069.
11. Ferguson, S.S., Barak, L.S., Zhang, J., and Caron, M.G. (1996). G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins. Can. J. Physiol. Pharmacol. 74, 1095-1110.
12. Furst, W., and Sandhoff, K. (1992). Activator proteins and topology of lysosomal sphingolipid catabolism. Biochim. Biophys. Acta 1126, 1-16.
13. Ghosh, T.K., Bian, J., and Gill, D.L. (1990). Intracellular calcium release mediated by sphingosine derivatives generated in cells. Science 248, 1653-1656.
14. Heringdorf, D.M., Lass, H., Alemany, R., Laser, K.T., Neumann, E., Zhang, C., Schmidt, M., Rauen, U., Jakobs, K.H., and Van Koppen, C.J. (1998). Sphingosine kinase-mediated Ca2+ signaling by G-protein-coupled receptors. EMBO J. 27, 2830-2837.
15. Hla, T., Lee, M., Ancellin, N., Liu, C.H., Thangada, S., Thompson, B.D., and Kluk, M. (1999). Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger? Biochem. Pharmacol. (in press).
16. Hla, T., and Maciag, T. (1990). An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors. J. Biol. Chem. 265, 9308-9313.
17. Hung, W.C., and Chuang, L.Y. (1996). Induction of apoptosis by sphingosine-1-phosphate in human hepatoma cells is associated with enhanced expression of bax gene product. Biochem. Biophys. Res. Commun. 229, 11-15.
18. Kohama, T., Olivera, A., Edsall, L., Nagiec, M.M., Dickson, R., and Spiegel, S. (1998). Molecular cloning and functional characterization of murine sphingosine kinase. J. Biol. Chem. 273, 23722-23728.
19. Lee, M.-J., Evans, M., and Hla, T. (1996). The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway. J. Biol. Chem. 271, 11272-11279.
20. Lee, M.-J., Thangada, S., Liu, C.H., Thompson, B.D., and Hla, T. (1998a). Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist. J. Biol. Chem. 273, 22105-22112.
21. Lee, M.J., Van Brocklyn, J.R., Thangada, S., Liu, C.H., Hand, A.R., Menzeleev, R., Spiegel, S., and Hla, T. (1998b). Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science 279, 1552-1555.
22. Liu, C.H., and Hla, T. (1997). The mouse gene for the inducible G-protein-coupled receptor EDG-1. Genomics 43, 15-24.
23. Mattie, M., Brooker, G., and Spiegel, S. (1994). Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway. J. Biol. Chem. 269, 3181-3188.
24. Moolenaar, W.H., Kranenburg, O., Postma, F.R., and Zondag, G.C. (1997). Lysophosphatidic acid: G-protein signaling and cellular responses. Curr. Opin. Cell Biol. 9, 168-173.
25. Mukherjee, S., Ghosh, R.N., and Maxfield, F.R. (1997). Endocytosis. Physiol. Rev. 77, 759-803.
26. Okamoto, H., Takuwa, N., Gonda, K., Okazaki, H., Chang, K., Yatomi, Y., Shigematsu, H., and Takuwa, Y. (1998). EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition. J. Biol. Chem. 273, 27104-27110.
27. Olivera, A., and Spiegel, S. (1993). Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature 365, 557-560.
28. Postma, F.R., Jalink, K., Hengeveld, T., and Moolenaar, W.H. (1996). Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor. EMBO J. 15, 2388-2392.
29. Richardson, D.R., and Ponka, P. (1997). The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells. Biochim. Biophys. Acta 1333, 1-40.
30. Sadahira, Y., Ruan, F., Hakomori, S., and Igarashi, Y. (1992). Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness. Proc. Natl. Acad. Sci. USA 89, 9686-9690.
31. Sandhoff, K., and Klein, A. (1994). Intracellular trafficking of glycosphingolipids: role of sphingolipid activator proteins in the topology of endocytosis and lysosomal digestion. FEBS Lett. 346, 103-107.
32. Spiegel, S., and Merrill, A.H., Jr. (1996). Sphingolipid metabolism and cell growth regulation. FASEB J. 10, 1388-1397.
33. Su, Y., Rosenthal, D., Smulson, M., and Spiegel, S. (1994). Sphingosine 1-phosphate, a novel signaling molecule, stimulates DNA binding activity of AP-1 in quiescent Swiss 3T3 fibroblasts. J. Biol. Chem. 269, 16512-16517.
34. Takada, Y., Kato, C., Kondo, S., Korenaga, R., and Ando, J. (1997). Cloning of cDNAs encoding G protein-coupled receptor expressed in human endothelial cells exposed to fluid shear stress. Biochem. Biophys. Res. Commun. 240, 737-741.
35. Tarasova, N.I., Stauber, R.H., Choi, J.K., Hudson, E.A., Czerwinski, G., Miller, J.L., Pavlakis, G.N., Michedja, C.J., and Wank, S.A. (1997). Visualization of G protein-coupled receptor trafficking with the aid of the green fluorescent protein. Endocytosis and recycling of cholecystokinin receptor type A. J. Biol. Chem. 272, 14817-14824.
36. Trejo, J., Hammes, S.R., and Coughlin, S.R. (1998). Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting. Proc. Natl. Acad. Sci. USA 95, 13698-13702.
37. Van Brocklyn, J.R., et al. (1998). Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor edg-1 and intracellular to regulate proliferation and survival. J. Cell Biol. 142, 229-240.
38. Van Koppen, C., Meyer, Z.U., Heringdorf, M., Laser, K.T., Zhang, C., Jakobs, K.H., Bunemann, M., and Pott, L. (1996). Activation of a high affinity Gi protein-coupled plasma membrane receptor by sphingosine-1-phosphate. J. Biol. Chem. 271, 2082-2087.
39. Wu, J., Spiegel, S., and Sturgill, T.W. (1995). Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism. J. Biol. Chem. 270, 11484-11488.
40. Xiao, Z., Zhang, N., Murphy, D.B., and Devreotes, P.N. (1997). Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation. J. Cell Biol. 339, 365-374.
41. Yatomi, Y., Igarashi, Y., Yang, L., Hisano, N., Qi, R., Asazuma, N., Satoh, K., Ozaki, Y., and Kume, S. (1997). Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum. J. Biochem. 121, 69-973.
42. Yatomi, Y., Ruan, F., Hakomori, S., and Igarashi, Y. (1995). Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets. Blood 86, 193-202.
43. Zhang, H., Desai, N.N., Olivera, A., Seki, T., Brooker, G., and Spiegel, S. (1991). Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. J. Cell Biol. 114, 155-167.
44. Zondag, G.C.M., Postma, F.R., Etten, I.V., Verlaan, I., and Moolenaar, W.H. (1998). Sphingosine 1-phosphate signaling through the G-protein-coupled receptor Edg-1. Biochem. J. 330, 605-609.