Lipid phosphate phosphatases and signaling

Journal of Lipid Research

Volumn 50, Issue SUPPL., 2009, Pages

  Brindley, David N ^a   Pilquil, Carlos ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Autotaxin; Ceramide 1 phosphate; Diacylglycerol; Lysophosphatidate; Phosphatidate; Sphingosine 1 phosphate

Indexed keywords

DRUG DERIVATIVE; LIPID PHOSPHATE PHOSPHATASE; LYSOPHOSPHOLIPID; PHOSPHATIDATE PHOSPHATASE; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1-PHOSPHATE;

ANIMAL; EXTRACELLULAR SPACE; HUMAN; INTRACELLULAR SPACE; METABOLISM; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; EXTRACELLULAR SPACE; HUMANS; INTRACELLULAR SPACE; LYSOPHOSPHOLIPIDS; PHOSPHATIDATE PHOSPHATASE; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 66349139391     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.R800055-JLR200     Document Type: Review

References (50)

1. Brindley, D. N. 2004. Lipid phosphate phosphatases and related proteins: signaling functions in development, cell division, and cancer. J. Cell. Biochem. 92: 900-912. (Pubitemid 44264240)
2. Sigal, Y. J., M. I. McDermott, and A. J. Morris. 2005. Integral membrane lipid phosphatases/phosphotransferases: common structure and diverse functions. Biochem. J. 387: 281-293. (Pubitemid 40575751)
3. Brindley, D. N., and D. W. Waggoner. 1998. Mammalian lipid phosphate phosphohydrolases. J. Biol. Chem. 273: 24281-24284. (Pubitemid 28454910)
4. Pyne, S., K. C. Kong, and P. I. Darroch. 2004. Lysophosphatidic acid and sphingosine 1-phosphate biology: the role of lipid phosphate phosphatases. Semin. Cell Dev. Biol. 15: 491-501. (Pubitemid 38953945)
5. Zhang, Q. X., C. S. Pilquil, J. Dewald, L. G. Berthiaume, and D. N. Brindley. 2000. Identification of structurally important domains of lipid phosphate phosphatase-1: implications for its sites of action. Biochem. J. 345: 181-184. (Pubitemid 30077155)
6. Long, J. S., N. J. Pyne, and S. Pyne. 2008. Lipid phosphate phosphatases form homo- and hetero-oligomers: catalytic competency, subcellular distribution and function. Biochem. J. 411: 371-377. (Pubitemid 351580189)
7. Burnett, C., P. Makridou, L. Hewlett, and K. Howard. 2004. Lipid phosphate phosphatases dimerise, but this interaction is not required for in vivo activity. BMC Biochem. 5: 2.
8. Moolenaar, W. H., L. A. van Meeteren, and B. N. Giepmans. 2004. The ins and outs of lysophosphatidic acid signaling. Bioessays. 26: 870-881. (Pubitemid 39128101)
9. Yue, J., K. Yokoyama, L. Balazs, D. L. Baker, D. Smalley, C. Pilquil, D. N. Brindley, and G. Tigyi. 2004. Mice with transgenic overexpression of lipid phosphate phosphatase-1 display multiple organotypic deficits without alteration in circulating lysophosphatidate level. Cell. Signal. 16: 385-399. (Pubitemid 37542413)
10. Mills, G. B., and W. H. Moolenaar. 2003. The emerging role of lysophosphatidic acid in cancer. Nat. Rev. Cancer. 3: 582-591. (Pubitemid 37328830)
11. Moolenaar, W. H. 2002. Lysophospholipids in the limelight: autotaxin takes center stage. J. Cell Biol. 158: 197-199.
12. Tigyi, G., and A. L. Parrill. 2003. Molecular mechanisms of lysophosphatidic acid action. Prog. Lipid Res. 42: 498-526. (Pubitemid 37237637)
13. Rivera, R., and J. Chun. 2008. Biological effects of lysophospholipids. Rev. Physiol. Biochem. Pharmacol. 160: 25-46.
14. Murph, M. M., J. Hurst-Kennedy, V. Newton, D. N. Brindley, and H. Radhakrishna. 2007. Lysophosphatidic acid decreases the nuclear localization and cellular abundance of the p53 tumor suppressor in A549 lung carcinoma cells. Mol. Cancer Res. 5: 1201-1211. (Pubitemid 350137115)
15. Samadi, N., C. Gaetano, I. S. Goping, and D. N. Brindley. Autotaxin protects MCF-7 breast cancer and MDA-MB-435 melanoma cells against Taxol-induced apoptosis. Oncogene. Epub ahead of print. December 15, 2008.
16. Brindley, D. N. 1993. Hepatic secretion of lysphosphatidylcholine: a novel transport system for polyunsaturated fatty acids and choline. J. Nutr. Biochem. 4: 442-449. (Pubitemid 23253654)
17. Fourcade, O., M. F. Simon, C. Viode, N. Rugani, F. Leballe, A. Ragab, B. Fournie, L. Sarda, and H. Chap. 1995. Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells. Cell. 80: 919-927.
18. Sano, T., D. Baker, T. Virag, A. Wada, Y. Yatomi, T. Kobayashi, Y. Igarashi, and G. Tigyi. 2002. Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood. J. Biol. Chem. 277: 21197-21206. (Pubitemid 34952255)
19. Takabe, K., S. W. Paugh, S. Milstien, and S. Spiegel. 2008. "Insideout" signaling of sphingosine-1-phosphate: therapeutic targets. Pharmacol. Rev. 60: 181-195. (Pubitemid 351962008)
20. English, D., Z. Welch, A. T. Kovala, K. Harvey, O. V. Volpert, D. N. Brindley, and J. G. Garcia. 2000. Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis. FASEB J. 14: 2255-2265.
21. Pyne, S., J. S. Long, N. T. Ktistakis, and N. J. Pyne. 2005. Lipid phosphate phosphatases and lipid phosphate signalling. Biochem. Soc. Trans. 33: 1370-1374. (Pubitemid 41779690)
22. Jasinska, R., Q. X. Zhang, C. Pilquil, I. Singh, J. Xu, J. Dewald, D. A. Dillon, L. G. Berthiaume, G. M. Carman, D.W.Waggoner, et al. 1999. Lipid phosphate phosphohydrolase-1 degrades exogenous glycerolipid and sphingolipid phosphate esters. Biochem. J. 340: 677-686. (Pubitemid 29312864)
23. Imai, A., T. Furui, T. Tamaya, and G. B. Mills. 2000. A gonadotropin-releasing hormone-responsive phosphatase hydrolyses lysophosphatidic acid within the plasma membrane of ovarian cancer cells. J. Clin. Endocrinol. Metab. 85: 3370-3375.
24. Tanyi, J. L., A. J. Morris, J. K.Wolf, X. Fang, Y. Hasegawa, R. Lapushin, N. Auersperg, Y. J. Sigal, R. A. Newman, E. A. Felix, et al. 2003. The human lipid phosphate phosphatase-3 decreases the growth, survival, and tumorigenesis of ovarian cancer cells: validation of the lysophosphatidic acid signaling cascade as a target for therapy in ovarian cancer. Cancer Res. 63: 1073-1082. (Pubitemid 36278441)
25. Smyth, S. S., V. A. Sciorra, Y. J. Sigal, Z. Pamuklar, Z. Wang, Y. Xu, G. D. Prestwich, and A. J. Morris. 2003. Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity. J. Biol. Chem. 278: 43214-43223. (Pubitemid 37345940)
26. Simon, M. F., A. Rey, I. Castan-Laurel, S. Gres, D. Sibrac, P. Valet, and J. S. Saulnier-Blache. 2002. Expression of ectolipid phosphate phosphohydrolases in 3T3F442A preadipocytes and adipocytes. Involvement in the control of lysophosphatidic acid production. J. Biol. Chem. 277: 23131-23136. (Pubitemid 34952137)
27. Tanyi, J. L., Y. Hasegawa, R. Lapushin, A. J. Morris, J. K. Wolf, A. Berchuck, K. Lu, D. I. Smith, K. Kalli, L. C. Hartmann, et al. 2003. Role of decreased levels of lipid phosphate phosphatase-1 in accumulation of lysophosphatidic acid in ovarian cancer. Clin. Cancer Res. 9: 3534-3545. (Pubitemid 37169216)
28. Bektas, M., S. G. Payne, H. Liu, S. Goparaju, S. Milstien, and S. Spiegel. 2005. A novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cells. J. Cell Biol. 169: 801-811. (Pubitemid 41002885)
29. Brindley, D. N., and A. U. Bräuer. 2009. Lipid mediators and modulators of neural function. In Handbook of Neurochemistry and Molecular Biology: Lysophosphatidate and Lysolipids. A. Lajtha, G. Gorraci, and G. Tettamanti, editor. Springer, New York. In press.
30. Zhao, Y., S. K. Kalari, P. V. Usatyuk, I. Gorshkova, D. He, T. Watkins, D. N. Brindley, C. Sun, R. Bittman, J. G. Garcia, et al. 2007. Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. J. Biol. Chem. 282: 14165-14177. (Pubitemid 47100473)
31. Hannun, Y. A., and L. M. Obeid. 2008. Principles of bioactive lipid signalling: lessons from sphingolipids. Nat. Rev. Mol. Cell Biol. 9: 139-150. (Pubitemid 351158911)
32. Mechtcheriakova, D., A.Wlachos, J. Sobanov, F. Bornancin, G. Zlabinger, T. Baumruker, and A. Billich. 2007. FTY720-phosphate is dephosphorylated by lipid phosphate phosphatase 3. FEBS Lett. 581: 3063-3068. (Pubitemid 46899051)
33. Yamanaka, M., Y. Anada, Y. Igarashi, and A. Kihara. 2008. A splicing isoform of LPP1, LPP1a, exhibits high phosphatase activity toward FTY720 phosphate. Biochem. Biophys. Res. Commun. 375: 675-679.
34. Pettus, B. J., K. Kitatani, C. E. Chalfant, T. A. Taha, T. Kawamori, J. Bielawski, L. M. Obeid, and Y. A. Hannun. 2005. The coordination of prostaglandin E2 production by sphingosine-1-phosphate and ceramide-1-phosphate. Mol. Pharmacol. 68: 330-335. (Pubitemid 41058296)
35. van Meeteren, L. A., P. Ruurs, E. Christodoulou, J. W. Goding, H. Takakusa, K. Kikuchi, A. Perrakis, T. Nagano, and W. H. Moolenaar. 2005. Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate. J. Biol. Chem. 280: 21155-21161. (Pubitemid 40805676)
36. Tomsig, J. L., A. H. Snyder, E. V. Berdyshev, A. Skobeleva, C. Mataya, V. Natarajan, D. N. Brindley, and K. R. Lynch. Lipid phosphate phosphohydrolase type 1 (LPP1) degrades extracellular lysophosphatidic acid in vivo. Biochem. J. Epub ahead of print. February 12, 2009.
37. Peest, U., S. C. Sensken, P. Andreani, P. Hanel, P. P. Van Veldhoven, and M. H. Graler. 2008. S1P-lyase independent clearance of extracellular sphingosine 1-phosphate after dephosphorylation and cellular uptake. J. Cell. Biochem. 104: 756-772. (Pubitemid 351830827)
38. Humtsoe, J. O., S. Feng, G. D. Thakker, J. Yang, J. Hong, and K. K. Wary. 2003. Regulation of cell-cell interactions by phosphatidic acid phosphatase 2b/VCIP. EMBO J. 22: 1539-1554. (Pubitemid 36417403)
39. Humtsoe, J. O., R. A. Bowling, Jr., S. Feng, and K. K. Wary. 2005. Murine lipid phosphate phosphohydrolase-3 acts as a cell-associated integrin ligand. Biochem. Biophys. Res. Commun. 335: 906-919. (Pubitemid 41188282)
40. Wary, K. K., and J. O. Humtsoe. 2005. Anti-lipid phosphate phosphohydrolase-3 (LPP3) antibody inhibits bFGF- and VEGF-induced capillary morphogenesis of endothelial cells. Cell Commun. Signal. 3: 9.
41. Long, J. S., K. Yokoyama, G. Tigyi, N. J. Pyne, and S. Pyne. 2006. Lipid phosphate phosphatase-1 regulates lysophosphatidic acidand platelet-derived- growth-factor-induced cell migration. Biochem. J. 394: 495-500. (Pubitemid 43342550)
42. Pettitt, T. R., A. Martin, T. Horton, C. Liossis, J. M. Lord, and M. J. Wakelam. 1997. Diacylglycerol and phosphatidate generated by phospholipases C and D, respectively, have distinct fatty acid compositions and functions. Phospholipase D-derived diacylglycerol does not activate protein kinase C in porcine aortic endothelial cells. J. Biol. Chem. 272: 17354-17359. (Pubitemid 27311161)
43. Zhang, C., D. L. Baker, S. Yasuda, N. Makarova, L. Balazs, L. R. Johnson, G. K. Marathe, T. M. McIntyre, Y. Xu, G. D. Prestwich, et al. 2004. Lysophosphatidic acid induces neointima formation through PPARgamma activation. J. Exp. Med. 199: 763-774. (Pubitemid 38375196)
44. Simon, M. F., D. Daviaud, J. P. Pradere, S. Gres, C. Guigne, M. Wabitsch, J. Chun, P. Valet, and J. S. Saulnier-Blache. 2005. Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor gamma2. J. Biol. Chem. 280: 14656-14662. (Pubitemid 40562811)
45. Long, J., P. Darroch, K. F. Wan, K. C. Kong, N. Ktistakis, N. J. Pyne, and S. Pyne. 2005. Regulation of cell survival by lipid phosphate phosphatases involves the modulation of intracellular phosphatidic acid and sphingosine 1-phosphate pools. Biochem. J. 391: 25-32. (Pubitemid 41445472)
46. Zhao, Y., P. V. Usatyuk, R. Cummings, B. Saatian, D. He, T. Watkins, A. Morris, E. W. Spannhake, D. N. Brindley, and V. Natarajan. 2005. Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells. Biochem. J. 385: 493-502. (Pubitemid 40165082)
47. Pilquil, C., J. Dewald, A. Cherney, I. Gorshkova, G. Tigyi, D. English, V. Natarajan, and D. N. Brindley. 2006. Lipid phosphate phosphatase-1 regulates lysophosphatidate-induced fibroblast migration by controlling phospholipase D2-dependent phosphatidate generation. J. Biol. Chem. 281: 38418-38429. (Pubitemid 46041965)
48. Morris, K. E., L. M. Schang, and D. N. Brindley. 2006. Lipid phosphate phosphatase-2 activity regulates S-phase entry of the cell cycle in Rat2 fibroblasts. J. Biol. Chem. 281: 9297-9306. (Pubitemid 43864645)
49. Zhang, N., J. P. Sundberg, and T. Gridley. 2000. Mice mutant for Ppap2c, a homolog of the germ cell migration regulator wunen, are viable and fertile. Genesis. 27: 137-140.
50. Gómez-Muñoz, A. 2006. Ceramide 1-phosphate/ceramide, a switch between life and death. Biochim. Biophys. Acta. 1758: 2049-2056. (Pubitemid 44911057)