Novel synthetic ceramide derivatives increase intracellular calcium levels and promote epidermal keratinocyte differentiation

Journal of Lipid Research

Volumn 48, Issue 9, 2007, Pages 1936-1943

  Yoo, Bin Kwon ^a   Chang, Deok Kim ^a   Youm, Jong Kyung ^b,c   Hyung, Sub Gwak ^c   Byeong, Deog Park ^c   Seung, Hun Lee ^b,d   Jeon, Saewha ^e   Bo, Joong Kim ^a   Seo, Young Joon ^a   Park, Jang Kyu ^a   Lee, Jeung Hoon ^a  

^a Chungnam National University   (South Korea)

^b Yonsei University   (South Korea)

^c NeoPharm Co Ltd   (South Korea)

^d Yonsei University College of Medicine   (South Korea)

^e Tego Science   (South Korea)

Author keywords

Intracellular calcium level; K6PC 4; K6PC 5; K6PC 9; Keratin 1; Mitogen activated protein kinase

Indexed keywords

CERAMIDE DERIVATIVE; CYTOKERATIN 1; INVOLUCRIN; K 10PC 5; K 12PC 5; K 16PC 5; K 6PC 4; K 6PC 5; K 6PC 9; KERATIN; N (1,3 DIHYDROXYPROPYL) 2 DECYL 3 OXO TETRADECANAMIDE; N (1,3 DIHYDROXYPROPYL) 2 DODECYL 3 OXO HEXADECANAMIDE; N (1,3 DIHYDROXYPROPYL) 2 HEXADECYL 3 OXO HEXADECANAMIDE; N (1,3 DIHYDROXYPROPYL) 2 HEXYL 3 OXO DECANAMIDE; N (2,3 DIHYDROXYPROPYL) 2 HEXYL 3 OXO DECANAMIDE; N ETHANOL 2 HEXYL 3 HYDROXY DECANAMIDE; N ETHANOL 3 OXO 2 TETRADECYL HEXADECYL OCTADECANAMIDE EICOSANAMIDE; PC 9S; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG SYNTHESIS; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN DISEASE; WESTERN BLOTTING;

CALCIUM; CELL DIFFERENTIATION; CELLS, CULTURED; CERAMIDES; HUMANS; INFANT, NEWBORN; KERATINOCYTES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3;

EID: 34548384398     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M700185-JLR200     Document Type: Article

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