DHCR7 mutations linked to higher vitamin D status allowed early human migration to Northern latitudes

BMC Evolutionary Biology

Volumn 13, Issue 1, 2013, Pages

  Kuan, Valerie ^a   Martineau, Adrian R ^a   Griffiths, Chris J ^a   Hyppönen, Elina ^b,c   Walton, Robert ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

Author keywords

DHCR7; Evolutionary selection; Fixation index; Long range haplotype test; Vitamin D

Indexed keywords

ALLELE; CALCIUM; FREQUENCY ANALYSIS; GENETIC VARIATION; HOMEOSTASIS; HOMOGENEITY; LATITUDE; METABOLISM; MIGRATION; MUTATION; PHYSIOLOGY; VITAMIN;

25 HYDROXYVITAMIN D; 25-HYDROXYVITAMIN D; 7 DEHYDROCHOLESTEROL; 7 DEHYDROCHOLESTEROL REDUCTASE; 7-DEHYDROCHOLESTEROL REDUCTASE; CALCIUM; DRUG DERIVATIVE; OXIDOREDUCTASE; VITAMIN D;

7-DEHYDROCHOLESTEROL; ALTITUDE; ARTICLE; EUROPE; GENE FREQUENCY; GENETICS; HUMAN; METABOLISM; MIGRATION; MOLECULAR EVOLUTION; MUTATION; SINGLE NUCLEOTIDE POLYMORPHISM; VITAMIN D DEFICIENCY;

ALTITUDE; CALCIUM; DEHYDROCHOLESTEROLS; EUROPE; EVOLUTION, MOLECULAR; GENE FREQUENCY; HUMAN MIGRATION; HUMANS; MUTATION; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; POLYMORPHISM, SINGLE NUCLEOTIDE; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84880020284     PISSN: None     EISSN: 14712148     Source Type: Journal    
DOI: 10.1186/1471-2148-13-144     Document Type: Article

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