Activation of the p38 MAPK/NF-κB pathway contributes to doxorubicin-induced inflammation and cytotoxicity in H9c2 cardiac cells

Molecular Medicine Reports

Volumn 8, Issue 2, 2013, Pages 603-608

  Guo, Run Min ^a,b   Xu, Wen Ming ^c   Lin, Jian Cong ^c   Mo, Li Qiu ^c   Hua, Xiao Xiao ^c   Xi Chen, Pei ^a   Wu, Keng ^b   Zheng, Dong Dan ^c   Feng, Jian Qiang ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Cardiotoxicity; Doxorubicin; H9c2 cells; Nuclear factor B; P38 mitogen activated protein kinase; Tumor necrosis factor

Indexed keywords

DOXORUBICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXPOSURE; HEART MUSCLE CELL; INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; DOXORUBICIN; ENZYME ACTIVATION; INFLAMMATION; MYOCYTES, CARDIAC; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA;

EID: 84879977630     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1554     Document Type: Article

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