메뉴 건너뛰기




Volumn 110, Issue 28, 2013, Pages

On the mechanism of recombination hotspot scanning during double-stranded DNA break resection

Author keywords

DNA end processing; Protein motor; Protein DNA interactions; Real time measurements; Single molecule biophysics

Indexed keywords

HELICASE; NUCLEASE;

EID: 84879967537     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1303035110     Document Type: Article
Times cited : (32)

References (39)
  • 1
    • 33845604556 scopus 로고    scopus 로고
    • DNA double-strand break repair: All's well that ends well
    • DOI 10.1146/annurev.genet.40.110405.090451
    • Wyman C, Kanaar R (2006) DNA double-strand break repair: All's well that ends well. Annu Rev Genet 40:363-383. (Pubitemid 44956790)
    • (2006) Annual Review of Genetics , vol.40 , pp. 363-383
    • Wyman, C.1    Kanaar, R.2
  • 2
    • 65549095526 scopus 로고    scopus 로고
    • Nucleases and helicases take center stage in homologous recombination
    • Mimitou EP, Symington LS (2009) Nucleases and helicases take center stage in homologous recombination. Trends Biochem Sci 34(5):264-272.
    • (2009) Trends Biochem Sci , vol.34 , Issue.5 , pp. 264-272
    • Mimitou, E.P.1    Symington, L.S.2
  • 3
    • 76749090482 scopus 로고    scopus 로고
    • The processing of double-stranded DNA breaks for recombinational repair by helicase-nuclease complexes
    • Yeeles JT, Dillingham MS (2010) The processing of double-stranded DNA breaks for recombinational repair by helicase-nuclease complexes. DNA Repair 9(3):276-285.
    • (2010) DNA Repair , vol.9 , Issue.3 , pp. 276-285
    • Yeeles, J.T.1    Dillingham, M.S.2
  • 4
    • 77449156020 scopus 로고    scopus 로고
    • Characterization of the mycobacterial AdnAB DNA motor provides insights into the evolution of bacterial motor-nuclease machines
    • Unciuleac MC, Shuman S (2010) Characterization of the mycobacterial AdnAB DNA motor provides insights into the evolution of bacterial motor-nuclease machines. J Biol Chem 285(4):2632-2641.
    • (2010) J Biol Chem , vol.285 , Issue.4 , pp. 2632-2641
    • Unciuleac, M.C.1    Shuman, S.2
  • 5
    • 57349157777 scopus 로고    scopus 로고
    • RecBCD enzyme and the repair of double-stranded DNA breaks
    • Dillingham MS, Kowalczykowski SC (2008) RecBCD enzyme and the repair of double-stranded DNA breaks. Microbiol Mol Biol Rev 72(4):642-671.
    • (2008) Microbiol Mol Biol Rev , vol.72 , Issue.4 , pp. 642-671
    • Dillingham, M.S.1    Kowalczykowski, S.C.2
  • 6
    • 84871340015 scopus 로고    scopus 로고
    • Bacterial DNA repair: Recent insights into the mechanism of RecBCD, AddAB and AdnAB
    • Wigley DB (2013) Bacterial DNA repair: Recent insights into the mechanism of RecBCD, AddAB and AdnAB. Nat Rev Microbiol 11(1):9-13.
    • (2013) Nat Rev Microbiol , vol.11 , Issue.1 , pp. 9-13
    • Wigley, D.B.1
  • 7
    • 0027511858 scopus 로고
    • The recombination hotspot chi is a regulatory sequence that acts by attenuating the nuclease activity of the E. coli RecBCD enzyme
    • DOI 10.1016/0092-8674(93)90162-J
    • Dixon DA, Kowalczykowski SC (1993) The recombination hotspot chi is a regulatory sequence that acts by attenuating the nuclease activity of the E. coli RecBCD enzyme. Cell 73(1):87-96. (Pubitemid 23115451)
    • (1993) Cell , vol.73 , Issue.1 , pp. 87-96
    • Dixon, D.A.1    Kowalczykowski, S.C.2
  • 8
    • 79959338446 scopus 로고    scopus 로고
    • Recombination hotspots and single-stranded DNA binding proteins couple DNA translocation to DNA unwinding by the AddAB helicase-nuclease
    • Yeeles JT, van Aelst K, Dillingham MS, Moreno-Herrero F (2011) Recombination hotspots and single-stranded DNA binding proteins couple DNA translocation to DNA unwinding by the AddAB helicase-nuclease. Mol Cell 42(6):806-816.
    • (2011) Mol Cell , vol.42 , Issue.6 , pp. 806-816
    • Yeeles, J.T.1    Van Aelst, K.2    Dillingham, M.S.3    Moreno-Herrero, F.4
  • 9
    • 0031444642 scopus 로고    scopus 로고
    • The translocating RecBCD enzyme stimulates recombination by directing RecA protein onto ssDNA in a chi-regulated manner
    • DOI 10.1016/S0092-8674(00)80315-3
    • Anderson DG, Kowalczykowski SC (1997) The translocating RecBCD enzyme stimulates recombination by directing RecA protein onto ssDNA in a chi-regulated manner. Cell 90(1):77-86. (Pubitemid 28009420)
    • (1997) Cell , vol.90 , Issue.1 , pp. 77-86
    • Anderson, D.G.1    Kowalczykowski, S.C.2
  • 10
  • 11
    • 0030917148 scopus 로고    scopus 로고
    • The recombination hotspot Chi is recognized by the translocating RecBCD enzyme as the single strand of DNA containing the sequence 5?-GCTGGTGG-3?
    • Bianco PR, Kowalczykowski SC (1997) The recombination hotspot Chi is recognized by the translocating RecBCD enzyme as the single strand of DNA containing the sequence 5?-GCTGGTGG-3?. Proc Natl Acad Sci USA 94(13):6706-6711.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.13 , pp. 6706-6711
    • Bianco, P.R.1    Kowalczykowski, S.C.2
  • 12
    • 33745838577 scopus 로고    scopus 로고
    • The AddAB helicase/ nuclease forms a stable complex with its cognate chi sequence during translocation
    • Chédin F, Handa N, Dillingham MS, Kowalczykowski SC (2006) The AddAB helicase/ nuclease forms a stable complex with its cognate chi sequence during translocation. J Biol Chem 281(27):18610- 18617.
    • (2006) J Biol Chem , vol.281 , Issue.27 , pp. 18610-18617
    • Chédin, F.1    Handa, N.2    Dillingham, M.S.3    Kowalczykowski, S.C.4
  • 13
    • 0026720049 scopus 로고
    • RecBCD enzyme is altered upon cutting DNA at a chi recombination hotspot
    • Taylor AF, Smith GR (1992) RecBCD enzyme is altered upon cutting DNA at a chi recombination hotspot. Proc Natl Acad Sci USA 89(12):5226-5230.
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.12 , pp. 5226-5230
    • Taylor, A.F.1    Smith, G.R.2
  • 14
    • 9144271294 scopus 로고    scopus 로고
    • Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks
    • DOI 10.1038/nature02988
    • Singleton MR, Dillingham MS, Gaudier M, Kowalczykowski SC, Wigley DB (2004) Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks. Nature 432(7014):187-193. (Pubitemid 39545843)
    • (2004) Nature , vol.432 , Issue.7014 , pp. 187-193
    • Singleton, M.R.1    Dillingham, M.S.2    Gaudier, M.3    Kowalczykowski, S.C.4    Wigley, D.B.5
  • 15
    • 84858796420 scopus 로고    scopus 로고
    • Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex
    • Saikrishnan K, et al. (2012) Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex. EMBO J 31(6):1568-1578.
    • (2012) EMBO J , vol.31 , Issue.6 , pp. 1568-1578
    • Saikrishnan, K.1
  • 16
    • 84861889126 scopus 로고    scopus 로고
    • Molecular determinants responsible for recognition of the single-stranded DNA regulatory sequence,?, by RecBCD enzyme
    • Handa N, et al. (2012) Molecular determinants responsible for recognition of the single-stranded DNA regulatory sequence, ?, by RecBCD enzyme. Proc Natl Acad Sci USA 109(23):8901-8906.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.23 , pp. 8901-8906
    • Handa, N.1
  • 17
    • 84861860703 scopus 로고    scopus 로고
    • Alteration of? Recognition by RecBCD reveals a regulated molecular latch and suggests a channel-bypass mechanism for biological control
    • Yang L, et al. (2012) Alteration of ? recognition by RecBCD reveals a regulated molecular latch and suggests a channel-bypass mechanism for biological control. Proc Natl Acad Sci USA 109(23):8907-8912.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.23 , pp. 8907-8912
    • Yang, L.1
  • 18
    • 79953177394 scopus 로고    scopus 로고
    • The AddAB helicase-nuclease catalyses rapid and processive DNA unwinding using a single Superfamily 1A motor domain
    • Yeeles JT, Gwynn EJ, Webb MR, Dillingham MS (2011) The AddAB helicase-nuclease catalyses rapid and processive DNA unwinding using a single Superfamily 1A motor domain. Nucleic Acids Res 39(6):2271-2285.
    • (2011) Nucleic Acids Res , vol.39 , Issue.6 , pp. 2271-2285
    • Yeeles, J.T.1    Gwynn, E.J.2    Webb, M.R.3    Dillingham, M.S.4
  • 19
  • 20
    • 0036111913 scopus 로고    scopus 로고
    • Magnetic tweezers: Micromanipulation and force measurement at the molecular level
    • Gosse C, Croquette V (2002) Magnetic tweezers: Micromanipulation and force measurement at the molecular level. Biophys J 82(6):3314-3329. (Pubitemid 34547674)
    • (2002) Biophysical Journal , vol.82 , Issue.6 , pp. 3314-3329
    • Gosse, C.1    Croquette, V.2
  • 21
    • 0141540814 scopus 로고    scopus 로고
    • A molecular throttle: The recombination hotspot chi controls DNA translocation by the RecBCD helicase
    • DOI 10.1016/S0092-8674(03)00681-0
    • Spies M, et al. (2003) A molecular throttle: The recombination hotspot chi controls DNA translocation by the RecBCD helicase. Cell 114(5):647-654. (Pubitemid 37159260)
    • (2003) Cell , vol.114 , Issue.5 , pp. 647-654
    • Spies, M.1    Bianco, P.R.2    Dillingham, M.S.3    Handa, N.4    Baskin, R.J.5    Kowalczykowski, S.C.6
  • 22
    • 36049052525 scopus 로고    scopus 로고
    • RecBCD Enzyme Switches Lead Motor Subunits in Response to chi Recognition
    • DOI 10.1016/j.cell.2007.09.023, PII S0092867407012111
    • Spies M, Amitani I, Baskin RJ, Kowalczykowski SC (2007) RecBCD enzyme switches lead motor subunits in response to chi recognition. Cell 131(4):694-705. (Pubitemid 350087199)
    • (2007) Cell , vol.131 , Issue.4 , pp. 694-705
    • Spies, M.1    Amitani, I.2    Baskin, R.J.3    Kowalczykowski, S.C.4
  • 23
    • 0032539693 scopus 로고    scopus 로고
    • A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics
    • SantaLucia J, Jr. (1998) A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics. Proc Natl Acad Sci USA 95(4):1460-1465.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.4 , pp. 1460-1465
    • SantaLucia Jr., J.1
  • 24
    • 27744507840 scopus 로고    scopus 로고
    • Velocity and processivity of helicase unwinding of double-stranded nucleic acids
    • DOI 10.1088/0953-8984/17/47/015, PII S0953898405078252
    • Betterton MD, Jülicher F (2005) Velocity and processivity of helicase unwinding of double-stranded nucleic acids. J Phys Condens Matter 17(47):S3851-S3869. (Pubitemid 41607429)
    • (2005) Journal of Physics Condensed Matter , vol.17 , Issue.47
    • Betterton, M.D.1    Julicher, F.2
  • 26
    • 84861442263 scopus 로고    scopus 로고
    • Active DNA unwinding dynamics during processive DNA replication
    • Morin JA, et al. (2012) Active DNA unwinding dynamics during processive DNA replication. Proc Natl Acad Sci USA 109(21):8115-8120.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.21 , pp. 8115-8120
    • Morin, J.A.1
  • 27
    • 5244325378 scopus 로고
    • Dynamical disorder: Passage through a fluctuating bottleneck
    • Zwanzig R (1992) Dynamical disorder: Passage through a fluctuating bottleneck. J Chem Phys 97:3587.
    • (1992) J Chem Phys , vol.97 , pp. 3587
    • Zwanzig, R.1
  • 28
    • 0001631778 scopus 로고
    • Rate processes with dynamical disorder
    • Zwanzig R (1990) Rate processes with dynamical disorder. Acc Chem Res 23(5): 148-152.
    • (1990) Acc Chem Res , vol.23 , Issue.5 , pp. 148-152
    • Zwanzig, R.1
  • 29
    • 77955605175 scopus 로고    scopus 로고
    • PcrA helicase dismantles RecA filaments by reeling in DNA in uniform steps
    • Park J, et al. (2010) PcrA helicase dismantles RecA filaments by reeling in DNA in uniform steps. Cell 142(4):544-555.
    • (2010) Cell , vol.142 , Issue.4 , pp. 544-555
    • Park, J.1
  • 30
    • 77954902959 scopus 로고    scopus 로고
    • Probing static disorder in Arrhenius kinetics by single-molecule force spectroscopy
    • Kuo TL, et al. (2010) Probing static disorder in Arrhenius kinetics by single-molecule force spectroscopy. Proc Natl Acad Sci USA 107(25):11336-11340.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.25 , pp. 11336-11340
    • Kuo, T.L.1
  • 31
    • 33747375815 scopus 로고    scopus 로고
    • Probing 3′-ssDNA loop formation in E. Coli RecBCD/RecBC-DNA complexes using non-natural DNA: A model for "Chi" recognition complexes
    • Wong CJ, Rice RL, Baker NA, Ju T, Lohman TM (2006) Probing 3′-ssDNA loop formation in E. coli RecBCD/RecBC-DNA complexes using non-natural DNA: A model for "Chi" recognition complexes. J Mol Biol 362(1):26-43.
    • (2006) J Mol Biol , vol.362 , Issue.1 , pp. 26-43
    • Wong, C.J.1    Rice, R.L.2    Baker, N.A.3    Ju, T.4    Lohman, T.M.5
  • 32
    • 77955246025 scopus 로고    scopus 로고
    • Visualizing helicases unwinding DNA at the single molecule level
    • Fili N, et al. (2010) Visualizing helicases unwinding DNA at the single molecule level. Nucleic Acids Res 38(13):4448-4457.
    • (2010) Nucleic Acids Res , vol.38 , Issue.13 , pp. 4448-4457
    • Fili, N.1
  • 33
    • 77954378226 scopus 로고    scopus 로고
    • Single-molecule imaging of Bacteroides fragilis AddAB reveals the highly processive translocation of a single motor helicase
    • Reuter M, Parry F, Dryden DT, Blakely GW (2010) Single-molecule imaging of Bacteroides fragilis AddAB reveals the highly processive translocation of a single motor helicase. Nucleic Acids Res 38(11):3721-3731.
    • (2010) Nucleic Acids Res , vol.38 , Issue.11 , pp. 3721-3731
    • Reuter, M.1    Parry, F.2    Dryden, D.T.3    Blakely, G.W.4
  • 36
    • 65549152342 scopus 로고    scopus 로고
    • Studying RecBCD helicase translocation along Chi-DNA using tethered particle motion with a stretching force
    • Fan HF, Li HW (2009) Studying RecBCD helicase translocation along Chi-DNA using tethered particle motion with a stretching force. Biophys J 96(5):1875-1883.
    • (2009) Biophys J , vol.96 , Issue.5 , pp. 1875-1883
    • Fan, H.F.1    Li, H.W.2
  • 38
    • 4344649856 scopus 로고    scopus 로고
    • Real-time observation of DNA translocation by the type I restriction modification enzyme EcoR124I
    • Seidel R, et al. (2004) Real-time observation of DNA translocation by the type I restriction modification enzyme EcoR124I. Nat Struct Mol Biol 11(9):838 -843.
    • (2004) Nat Struct Mol Biol , vol.11 , Issue.9 , pp. 838-843
    • Seidel, R.1
  • 39
    • 43449094034 scopus 로고    scopus 로고
    • Homologous Recombination in Real Time: DNA Strand Exchange by RecA
    • DOI 10.1016/j.molcel.2008.03.010, PII S1097276508002104
    • van der Heijden T, et al. (2008) Homologous recombination in real time: DNA strand exchange by RecA. Mol Cell 30(4):530-538. (Pubitemid 351672371)
    • (2008) Molecular Cell , vol.30 , Issue.4 , pp. 530-538
    • Van Der Heijden, T.1    Modesti, M.2    Hage, S.3    Kanaar, R.4    Wyman, C.5    Dekker, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.