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Volumn 109, Issue 21, 2012, Pages 8115-8120

Active DNA unwinding dynamics during processive DNA replication

Author keywords

Molecular motors; Replicative DNA polymerase; Single molecule; Strand displacement

Indexed keywords

DNA POLYMERASE; DOUBLE STRANDED DNA; PRIMER DNA;

EID: 84861442263     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1204759109     Document Type: Article
Times cited : (65)

References (39)
  • 1
    • 0035951425 scopus 로고    scopus 로고
    • A General model for nucleic acid helicases and their "coupling" within macromolecular machines
    • von Hippel PH, Delagoutte E (2001) A General model for nucleic acid helicases and their "coupling" within macromolecular machines. Cell 104:177-190.
    • (2001) Cell , vol.104 , pp. 177-190
    • Von Hippel, P.H.1    Delagoutte, E.2
  • 2
    • 19644399070 scopus 로고    scopus 로고
    • DNA synthesis provides the driving force to accelerate DNA unwinding by a helicase
    • DOI 10.1038/nature03615
    • Stano NM, et al. (2005) DNA synthesis provides the driving force to accelerate DNA unwinding by a helicase. Nature 435:370-373. (Pubitemid 40745548)
    • (2005) Nature , vol.435 , Issue.7040 , pp. 370-373
    • Stano, N.M.1    Jeong, Y.-J.2    Donmez, I.3    Tummalapalli, P.4    Levin, M.K.5    Patel, S.S.6
  • 4
    • 0025815855 scopus 로고
    • Protein-priming of DNA replication
    • Salas M (1991) Protein-priming of DNA replication. Annu Rev Biochem 60:39-71.
    • (1991) Annu Rev Biochem , vol.60 , pp. 39-71
    • Salas, M.1
  • 6
    • 8844274078 scopus 로고    scopus 로고
    • Insights into strand displacement and processivity from the crystal structure of the protein-primed DNA polymerase of bacteriophage Phi29
    • DOI 10.1016/j.molcel.2004.10.019, PII S1097276504006458
    • Kamtekar S, et al. (2004) Insights into strand displacement and processivity from the crystal structure of the protein-primed DNA polymerase of bacteriophage Phi29. Mol Cell 16:609-618. (Pubitemid 39531883)
    • (2004) Molecular Cell , vol.16 , Issue.4 , pp. 609-618
    • Kamtekar, S.1    Berman, A.J.2    Wang, J.3    Lazaro, J.M.4    De Vega, M.5    Blanco, L.6    Salas, M.7    Steitz, T.A.8
  • 7
    • 0033786801 scopus 로고    scopus 로고
    • Structure and function of hexameric helicases
    • Patel SS, Picha KM (2000) Structure and function of hexameric helicases. Annu Rev Biochem 69:651-697.
    • (2000) Annu Rev Biochem , vol.69 , pp. 651-697
    • Patel, S.S.1    Picha, K.M.2
  • 8
    • 33746375404 scopus 로고    scopus 로고
    • Mechanism of DNA translocation in a replicative hexameric helicase
    • DOI 10.1038/nature04943, PII NATURE04943
    • Enemark EJ, Joshua-Tor L (2006) Mechanism of DNA translocation in a replicative hexameric helicase. Nature 442:270-275. (Pubitemid 44114897)
    • (2006) Nature , vol.442 , Issue.7100 , pp. 270-275
    • Enemark, E.J.1    Joshua-Tor, L.2
  • 10
    • 0035150184 scopus 로고    scopus 로고
    • Unwinding the 'Gordian knot' of helicase action
    • DOI 10.1016/S0968-0004(00)01734-5, PII S0968000400017345
    • Soultanas P, Wigley DB (2001) Unwinding the 'Gordian knot' of helicase action. Trends in Biochem Sci 26:47-54. (Pubitemid 32124710)
    • (2001) Trends in Biochemical Sciences , vol.26 , Issue.1 , pp. 47-54
    • Soultanas, P.1    Wigley, D.B.2
  • 11
    • 41349092240 scopus 로고    scopus 로고
    • Opening of nucleic-acid double strands by helicases: Active versus passive opening
    • Betterton MD, Julicher F (2005) Opening of nucleic-acid double strands by helicases: Active versus passive opening. Phys Rev E 71:11904-11911.
    • (2005) Phys Rev E , vol.71 , pp. 11904-11911
    • Betterton, M.D.1    Julicher, F.2
  • 12
    • 0026660346 scopus 로고
    • Site-directed mutagenesis at the Exo III motif of Phi29 DNA polymerase; overlapping structural domains for the 3′-5′ exonuclease and strand-displacement activities
    • Soengas MS, et al. (1992) Site-directed mutagenesis at the Exo III motif of Phi29 DNA polymerase; overlapping structural domains for the 3′-5′ exonuclease and strand-displacement activities. EMBO J 11:4227-4237.
    • (1992) EMBO J , vol.11 , pp. 4227-4237
    • Soengas, M.S.1
  • 13
    • 0030024985 scopus 로고    scopus 로고
    • Overstretching B-DNA: The elastic response of individual double-stranded and single-stranded DNA molecules
    • Smith SB, Cui Y, Bustamante C (1996) Overstretching B-DNA: The elastic response of individual double-stranded and single-stranded DNA molecules. Science 271:795-799.
    • (1996) Science , vol.271 , pp. 795-799
    • Smith, S.B.1    Cui, Y.2    Bustamante, C.3
  • 14
    • 70349213246 scopus 로고    scopus 로고
    • Proofreading dynamics of a processive DNA polymerase
    • Ibarra B, et al. (2009) Proofreading dynamics of a processive DNA polymerase. EMBO J 28:2794-2802.
    • (2009) EMBO J , vol.28 , pp. 2794-2802
    • Ibarra, B.1
  • 15
    • 0028172978 scopus 로고
    • 3′ → 5′ exonuclease active site of phi 29 DNA polymerase. Evidence favouring a metal ion-assisted reaction mechanism
    • Esteban JA, Soengas MS, Salas M, Blanco L (1994) 3′ → 5′ exonuclease active site of phi 29 DNA polymerase. Evidence favouring a metal ion-assisted reaction mechanism. J Biol Chem 269:31946-31954.
    • (1994) J Biol Chem , vol.269 , pp. 31946-31954
    • Esteban, J.A.1    Soengas, M.S.2    Salas, M.3    Blanco, L.4
  • 18
    • 58049202845 scopus 로고    scopus 로고
    • Impediment of E. coli UvrD by DNA-destabilizing force reveals a strained-inchworm mechanism of DNA unwinding
    • Sun B, et al. (2008) Impediment of E. coli UvrD by DNA-destabilizing force reveals a strained-inchworm mechanism of DNA unwinding. EMBO J 27:3279-3287.
    • (2008) EMBO J , vol.27 , pp. 3279-3287
    • Sun, B.1
  • 19
    • 73649092707 scopus 로고    scopus 로고
    • Single-molecule study of DNA polymerization activity of HIV-1 reverse transcriptase on DNA templates
    • Kim S, Schroeder CM, Xie XS (2010) Single-molecule study of DNA polymerization activity of HIV-1 reverse transcriptase on DNA templates. J Mol Biol 395:995-1006.
    • (2010) J Mol Biol , vol.395 , pp. 995-1006
    • Kim, S.1    Schroeder, C.M.2    Xie, X.S.3
  • 20
    • 77958475756 scopus 로고    scopus 로고
    • DnaB helicase activity is modulated by DNA geometry and force
    • Ribeck N, Kaplan DL, Bruck I, Saleh OA (2010) DnaB helicase activity is modulated by DNA geometry and force. Biophys J 99:2170-2179.
    • (2010) Biophys J , vol.99 , pp. 2170-2179
    • Ribeck, N.1    Kaplan, D.L.2    Bruck, I.3    Saleh, O.A.4
  • 21
    • 34250766751 scopus 로고    scopus 로고
    • Single-Molecule Studies Reveal Dynamics of DNA Unwinding by the Ring-Shaped T7 Helicase
    • DOI 10.1016/j.cell.2007.04.038, PII S0092867407005843
    • Johnson DS, Bai L, Smith BY, Patel SS, Wang MD (2007) Single-molecule studies reveal dynamics of DNA unwinding by the ring-shaped T7 helicase. Cell 129:1299-1309. (Pubitemid 46962089)
    • (2007) Cell , vol.129 , Issue.7 , pp. 1299-1309
    • Johnson, D.S.1    Bai, L.2    Smith, B.Y.3    Patel, S.S.4    Wang, M.D.5
  • 23
    • 0029982348 scopus 로고    scopus 로고
    • Analysis and suppression of DNA polymerase pauses associated with a trinucleotide consensus
    • DOI 10.1093/nar/24.14.2774
    • Mytelka DS, Chamberlin MJ (1996) Analysis and suppression of DNA polymerase pauses associated with a trinucleotide consensus. Nucleic Acids Res 24:2774-2781. (Pubitemid 26239748)
    • (1996) Nucleic Acids Research , vol.24 , Issue.14 , pp. 2774-2781
    • Mytelka, D.S.1    Chamberlin, M.J.2
  • 24
    • 73949097615 scopus 로고    scopus 로고
    • Single molecule measurement of the 'speed limit' of a DNA polymerase
    • Schwartz JJ, Quake SR (2009) Single molecule measurement of the 'speed limit' of a DNA polymerase. Proc Natl Acad Sci USA 106:20294-20299.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 20294-20299
    • Schwartz, J.J.1    Quake, S.R.2
  • 25
    • 0037229160 scopus 로고    scopus 로고
    • Substitutions at Phe61 in the β3-β4 hairpin of HIV-1 reverse transcriptase reveal a role for the fingers subdomain in strand displacement DNA synthesis
    • DOI 10.1016/S0022-2836(02)01225-1
    • Fisher TS, Darden T, Prasad VR (2003) Substitutions at Phe61 in the β3-β4 hairpin of HIV- 1 reverse transcriptase reveal a role for the fingers subdomain in strand displacement DNA synthesis. J Mol Biol 325:443-459. (Pubitemid 36062675)
    • (2003) Journal of Molecular Biology , vol.325 , Issue.3 , pp. 443-459
    • Fisher, T.S.1    Darden, T.2    Prasad, V.R.3
  • 26
    • 1342313235 scopus 로고    scopus 로고
    • The structural mechanism of translocation and helicase activity in T7 RNA polymerase
    • DOI 10.1016/S0092-8674(04)00120-5, PII S0092867404001205
    • Yin YW, Steitz TA (2004) The structural mechanism of translocation and helicase activity in T7 RNA polymerase. Cell 116:393-404. (Pubitemid 38366316)
    • (2004) Cell , vol.116 , Issue.3 , pp. 393-404
    • Yin, Y.W.1    Steitz, T.A.2
  • 27
    • 34249861631 scopus 로고    scopus 로고
    • Participation of the fingers subdomain of Escherichia coli DNA polymerase I in the strand displacement synthesis of DNA
    • DOI 10.1074/jbc.M611242200
    • Singh K, Srivastava A, Patel SS, Modak MJ (2007) Participation of the fingers subdomain of escherichia coli DNA polymerase I in the strand displacement synthesis of DNA. J Biol Chem 282:10594-10604. (Pubitemid 47093396)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.14 , pp. 10594-10604
    • Singh, K.1    Srivastava, A.2    Patel, S.S.3    Modak, M.J.4
  • 28
    • 0024292414 scopus 로고
    • Characterization of base-pair opening in deoxynucleotide duplexes using catalyzed exchange of the imino proton
    • Leroy JL, Kochoyan M, Huynh-Dinh T, Guéron M (1988) Characterization of base-pair opening in deoxynucleotide duplexes using catalyzed exchange of the imino proton. J Mol Biol 200:223-238.
    • (1988) J Mol Biol , vol.200 , pp. 223-238
    • Leroy, J.L.1    Kochoyan, M.2    Huynh-Dinh, T.3    Guéron, M.4
  • 29
    • 68349112594 scopus 로고    scopus 로고
    • Functional importance of bacteriophage Phi29 DNA polymerase residue Tyr148 in primer-terminus stabilisation at the 3′-5′ exonuclease active site
    • Pérez-Arnaiz P, Lázaro JM, Salas M, de Vega M (2009) Functional importance of bacteriophage Phi29 DNA polymerase residue Tyr148 in primer-terminus stabilisation at the 3′-5′ exonuclease active site. J Mol Biol 391:797-807.
    • (2009) J Mol Biol , vol.391 , pp. 797-807
    • Pérez-Arnaiz, P.1    Lázaro, J.M.2    Salas, M.3    De Vega, M.4
  • 30
    • 0033600752 scopus 로고    scopus 로고
    • Replication slippage of different DNA polymerases is inversely related to their strand displacement efficiency
    • Canceill D, Viguera E, Ehrlich SD (1999) Replication slippage of different DNA polymerases is inversely related to their strand displacement efficiency. J Biol Chem 274:27481-27490.
    • (1999) J Biol Chem , vol.274 , pp. 27481-27490
    • Canceill, D.1    Viguera, E.2    Ehrlich, S.D.3
  • 31
    • 70450269266 scopus 로고    scopus 로고
    • Strand displacement by DNA polymerase III occurs through a link to single-stranded DNA-binding protein coating the lagging strand template
    • Yuan Q, McHenry CS (2009) Strand displacement by DNA polymerase III occurs through a link to single-stranded DNA-binding protein coating the lagging strand template. J Biol Chem 284:31672-31679.
    • (2009) J Biol Chem , vol.284 , pp. 31672-31679
    • Yuan, Q.1    McHenry, C.S.2
  • 32
    • 0032518398 scopus 로고    scopus 로고
    • Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution
    • DOI 10.1038/34593
    • Doublie S, Tabor S, Long AM, Richardson CC, Ellenberger T (1998) Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution. Nature 391:251-258. (Pubitemid 28099004)
    • (1998) Nature , vol.391 , Issue.6664 , pp. 251-258
    • Doublie, S.1    Tabor, S.2    Long, A.M.3    Richardson, C.C.4    Ellenberger, T.5
  • 33
    • 0035369086 scopus 로고    scopus 로고
    • Structure of the replicating complex of a pol α family DNA polymerase
    • DOI 10.1016/S0092-8674(01)00367-1
    • Franklin MC, Wang J, Steitz TA (2001) Structure of the replicating complex of a Polαfamily DNA polymerase. Cell 105:657-667. (Pubitemid 32524118)
    • (2001) Cell , vol.105 , Issue.5 , pp. 657-667
    • Franklin, M.C.1    Wang, J.2    Steitz, T.A.3
  • 34
    • 0030670510 scopus 로고    scopus 로고
    • A hexameric helicase encircles one DNA strand and excludes the other during DNA unwinding
    • DOI 10.1021/bi971644v
    • Hacker KJ, Johnson KA (1997) A hexameric helicase encircles one DNA strand and excludes the other during DNA unwinding. Biochemistry 36:14080-14087. (Pubitemid 27509843)
    • (1997) Biochemistry , vol.36 , Issue.46 , pp. 14080-14087
    • Hacker, K.J.1    Johnson, K.A.2
  • 35
    • 0031465797 scopus 로고    scopus 로고
    • Asymmetric interactions of hexameric bacteriophage T7 DNA helicase with the 5'- and 3'-tails of the forked DNA substrate
    • DOI 10.1074/jbc.272.51.32267
    • Ahnert P, Patel SS (1997) Asymmetric interactions of hexameric bacteriophage T7 DNA helicase with the 5′-and 3′-tails of the forked DNA substrate. J Biol Chem 272:32267-32273. (Pubitemid 28011905)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.51 , pp. 32267-32273
    • Ahnert, P.1    Patel, S.S.2
  • 36
    • 34547118809 scopus 로고    scopus 로고
    • Nucleic acid unwinding by hepatitis C virus and bacteriophage T7 helicases is sensitive to base pair stability
    • DOI 10.1074/jbc.M702136200
    • Donmez I, Rajagopal V, Jeong Y-J, Patel SS (2007) Nucleic acid unwinding by hepatitis C virus and bacteriophage T7 helicases is sensitive to base pair stability. J Biol Chem 282:21116-21123. (Pubitemid 47099898)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.29 , pp. 21116-21123
    • Donmez, I.1    Rajagopal, V.2    Jeong, Y.-J.3    Patel, S.S.4
  • 38
    • 0037286741 scopus 로고    scopus 로고
    • Optical-trap force transducer that operates by direct measurement of light momentum
    • DOI 10.1016/S0076-6879(03)61009-8
    • Smith SB, Cui Y, Bustamante C (2003) Optical-trap force transducer that operates by direct measurement of light momentum. Methods Enzymol 361:134-162. (Pubitemid 36240997)
    • (2003) Methods in Enzymology , vol.361 , pp. 134-162
    • Smith, S.B.1    Cui, Y.2    Bustamante, C.3
  • 39
    • 0028879334 scopus 로고
    • Purification of bacteriophage Phi29 DNA polymerase
    • Lazaro JMBL, Salas M (1995) Purification of bacteriophage Phi29 DNA polymerase. Methods Enzymol 262:42-49.
    • (1995) Methods Enzymol , vol.262 , pp. 42-49
    • Lazaro, J.1    Salas, M.2


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