Alteration of χ recognition by RecBCD reveals a regulated molecular latch and suggests a channel-bypass mechanism for biological control

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 23, 2012, Pages 8907-8912

  Yang, Liang ^a   Handa, Naofumi ^a,b   Liu, Bian ^a   Dillingham, Mark S ^c   Wigley, Dale B ^d   Kowalczykowski, Stephen C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Allosteric switch; Protein DNA interactions

Indexed keywords

DNA FRAGMENT; EXODEOXYRIBONUCLEASE V; HELICASE; NUCLEASE; SINGLE STRANDED DNA;

ALLOSTERISM; ALPHA HELIX; ARTICLE; DNA DEGRADATION; DNA RECOMBINATION; DOUBLE STRANDED DNA BREAK; ESCHERICHIA COLI; GENE SWITCHING; GENETIC ANALYSIS; GENETIC VARIABILITY; MOLECULAR GENETICS; MOLECULAR RECOGNITION; MUTANT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; SINGLE NUCLEOTIDE POLYMORPHISM; SITE DIRECTED MUTAGENESIS;

DNA REPAIR; DNA, SINGLE-STRANDED; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; EXODEOXYRIBONUCLEASE V; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; REGULATORY SEQUENCES, NUCLEIC ACID; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI;

EID: 84861860703     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1206081109     Document Type: Article

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