Toward a siRNA-containing nanoparticle targeted to breast cancer cells and the tumor microenvironment

International Journal of Pharmaceutics

Volumn 434, Issue 1-2, 2012, Pages 9-19

  Gomes Da Silva, Lígia C ^a,b   Santos, Adriana O ^a,b   Bimbo, Luís M ^a,b   Moura, Vera ^a,b   Ramalho, José S ^c   Pedroso De Lima, Maria C ^a,d   Simões, Sérgio ^a,b   Moreira, João N ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Breast cancer; Dual targeted delivery; Ligand mediated targeting; siRNA; Stable nucleic acid lipid particles (SNALP)

Indexed keywords

1,2 BIS STEAROYL GLYCERO 3 PHOSPHOCHOLINE; 1,2 DIOLEOYL 3 DIMETHYLAMMONIUM PROPANE; 1,2 DISTEAROYL SN GLYCERO 3 PHOSPATIDYLETHANOLAMINE N [MALEIMIDE (POLYETHYLENE GLYCOL)2000]; ALPHA PHOSPHOETHANOLAMINE N (LISSAMINE RHODAMINE B SULFONYL); ENHANCED GREEN FLUORESCENT PROTEIN; LIPID; LIPOSOME; MACROGOL; N PALMITOYL SPHINGOSINE 1 [SUCCINYL(METHOXYPOLYETHYLENE GLYCOL)2000]; NANOCARRIER; NUCLEIC ACID; NUCLEOLIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERNALIZATION; LIPOSOMAL DELIVERY; MOLECULARLY TARGETED THERAPY; PRIORITY JOURNAL; TUMOR MICROENVIRONMENT;

BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; DOWN-REGULATION; ENDOTHELIAL CELLS; FEMALE; GREEN FLUORESCENT PROTEINS; HUMANS; LIPOSOMES; LYSOSOMES; NANOPARTICLES; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDES; PHOSPHOPROTEINS; POLYETHYLENE GLYCOLS; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; TUMOR MICROENVIRONMENT;

EID: 84864129727     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.05.018     Document Type: Article

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