SCOPUS 정보 검색 플랫폼

Volumn 4, Issue 7, 2013, Pages 1099-1104

Design of potential bisubstrate inhibitors against Mycobacterium tuberculosis (Mtb) 1-deoxy-d-xylulose 5-phosphate reductoisomerase (Dxr)-evidence of a novel binding mode

(11) San Jose, Géraldine a Jackson, Emily R a Uh, Eugene a Johny, Chinchu b Haymond, Amanda b Lundberg, Lindsay b Pinkham, Chelsea b Kehn Hall, Kylene b Boshoff, Helena I c Couch, Robin D b Dowd, Cynthia S a

a GEORGE WASHINGTON UNIVERSITY (United States)

b GEORGE MASON UNIVERSITY (United States)

c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 DEOXYXYLULOSE 5 PHOSPHATE REDUCTOISOMERASE INHIBITOR; 3 (N ACETYL N HYDROXYAMINO)PROPYLPHOSPHONIC ACID; FOSMIDOMYCIN; ISOMERASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG BINDING; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME BINDING; ENZYME INHIBITION; ENZYME SUBSTRATE; IC 50; LIPOPHILICITY; MOLECULAR DOCKING; MOLECULAR MODEL; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; PROTEIN STRUCTURE;

MYCOBACTERIUM TUBERCULOSIS;

EID: 84879868143 PISSN: 20402503 EISSN: 20402511 Source Type: Journal
DOI: 10.1039/c3md00085k Document Type: Article

Times cited : (28)

References (42)

1
- 84875422921
- C. Dye P. Glaziou K. Floyd M. Raviglione Annu. Rev. Public Health 2013 34 271 286
- (2013) Annu. Rev. Public Health , vol.34 , pp. 271-286
- Dye, C.¹ Glaziou, P.² Floyd, K.³ Raviglione, M.⁴

2
- 67349147683
- WHO Press, Geneva, Switzerland
- Global Tuberculosis Control 2009: Epidemiology, Strategy, Financing, WHO Press, Geneva, Switzerland, 2009
- (2009) Global Tuberculosis Control 2009: Epidemiology, Strategy, Financing

3
- 0003424751
- Geneva, Switzerland Who
- WHO, Treatment of Tuberculosis: Guideline for National Programmes, Geneva, Switzerland, 2003
- (2003) Treatment of Tuberculosis: Guideline for National Programmes

4
- 33645119729
- A. Wright MMWR Morb. Mortal. Wkly. Rep. 2006 55 301 305
- (2006) MMWR Morb. Mortal. Wkly. Rep. , vol.55 , pp. 301-305
- Wright, A.¹

5
- 73449138152
- WHO Press, Geneva, Switzerland
- Emergency Update, 2008: Guidelines for the programmatic management of drug-resistant tuberculosis, WHO Press, Geneva, Switzerland, 2008
- (2008) Emergency Update, 2008: Guidelines for the Programmatic Management of Drug-resistant Tuberculosis

6
- 84856711991
- Z. F. Udwadia R. A. Amale K. K. Ajbani C. Rodrigues Clin. Infect. Dis. 2012 54 579 581
- (2012) Clin. Infect. Dis. , vol.54 , pp. 579-581
- Udwadia, Z.F.¹ Amale, R.A.² Ajbani, K.K.³ Rodrigues, C.⁴

7
- 0041589189
- C. A. Testa M. J. Brown Curr. Pharm. Biotechnol. 2003 4 248 259
- (2003) Curr. Pharm. Biotechnol. , vol.4 , pp. 248-259
- Testa, C.A.¹ Brown, M.J.²

8
- 8644261622
- P. J. Proteau Bioorg. Chem. 2004 32 483 493
- (2004) Bioorg. Chem. , vol.32 , pp. 483-493
- Proteau, P.J.¹

9
- 42549100536
- A. C. Brown T. Parish BMC Microbiol. 2008 8 78
- (2008) BMC Microbiol. , vol.8 , pp. 78
- Brown, A.C.¹ Parish, T.²

10
- 0019252767
- M. Okuhara Y. Kuroda T. Goto M. Okamoto H. Terano M. Kohsaka H. Aoki H. Imanaka J. Antibiot. 1980 33 13 17
- (1980) J. Antibiot. , vol.33 , pp. 13-17
- Okuhara, M.¹ Kuroda, Y.² Goto, T.³ Okamoto, M.⁴ Terano, H.⁵ Kohsaka, M.⁶ Aoki, H.⁷ Imanaka, H.⁸

11
- 0032558613
- T. Kuzuyama T. Shimizu S. Takahashi H. Seto Tetrahedron Lett. 1998 39 7913 7916
- (1998) Tetrahedron Lett. , vol.39 , pp. 7913-7916
- Kuzuyama, T.¹ Shimizu, T.² Takahashi, S.³ Seto, H.⁴

12
- 0033520336
- H. Jomaa J. Wiesner S. Sanderbrand B. Altincicek C. Weidemeyer M. Hintz I. Turbachova M. Eberl J. Zeidler H. K. Lichtenthaler D. Soldati E. Beck Science 1999 285 1573 1576
- (1999) Science , vol.285 , pp. 1573-1576
- Jomaa, H.¹ Wiesner, J.² Sanderbrand, S.³ Altincicek, B.⁴ Weidemeyer, C.⁵ Hintz, M.⁶ Turbachova, I.⁷ Eberl, M.⁸ Zeidler, J.⁹ Lichtenthaler, H.K.¹⁰ Soldati, D.¹¹ Beck, E.¹²

13
- 34248596742
- N. Singh G. Cheve M. A. Avery C. R. McCurdy Curr. Pharm. Des. 2007 13 1161 1177
- (2007) Curr. Pharm. Des. , vol.13 , pp. 1161-1177
- Singh, N.¹ Cheve, G.² Avery, M.A.³ McCurdy, C.R.⁴

14
- 2442581292
- Y. Nolan D. Martin V. A. Campbell M. A. Lynch J. Neuroimmunol. 2004 151 12 23
- (2004) J. Neuroimmunol. , vol.151 , pp. 12-23
- Nolan, Y.¹ Martin, D.² Campbell, V.A.³ Lynch, M.A.⁴

15
- 2842613801
- Y. Sakamoto S. Furukawa H. Ogihara M. Yamasaki Biosci., Biotechnol., Biochem. 2003 67 2030 2033
- (2003) Biosci., Biotechnol., Biochem. , vol.67 , pp. 2030-2033
- Sakamoto, Y.¹ Furukawa, S.² Ogihara, H.³ Yamasaki, M.⁴

16
- 28844484972
- R. K. Dhiman M. L. Schaeffer A. M. Bailey C. A. Testa H. Scherman D. C. Crick J. Bacteriol. 2005 187 8395 8402
- (2005) J. Bacteriol. , vol.187 , pp. 8395-8402
- Dhiman, R.K.¹ Schaeffer, M.L.² Bailey, A.M.³ Testa, C.A.⁴ Scherman, H.⁵ Crick, D.C.⁶

17
- 80255122793
- E. Uh E. R. Jackson G. San Jose M. Maddox R. E. Lee R. E. Lee H. I. Boshoff C. S. Dowd Bioorg. Med. Chem. Lett. 2011 21 6973 6976
- (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 6973-6976
- Uh, E.¹ Jackson, E.R.² San Jose, G.³ Maddox, M.⁴ Lee, R.E.⁵ Lee, R.E.⁶ Boshoff, H.I.⁷ Dowd, C.S.⁸

18
- 84867507359
- E. S. McKenney M. Sargent H. Khan E. Uh E. R. Jackson G. San Jose R. D. Couch C. S. Dowd M. L. van Hoek PLoS One 2012 7 e38167
- (2012) PLoS One , vol.7 , pp. 38167
- McKenney, E.S.¹ Sargent, M.² Khan, H.³ Uh, E.⁴ Jackson, E.R.⁵ San Jose, G.⁶ Couch, R.D.⁷ Dowd, C.S.⁸ Van Hoek, M.L.⁹

19
- 79960652249
- M. Andaloussi L. M. Henriksson A. Wieckowska M. Lindh C. Bjorkelid A. M. Larsson S. Suresh H. Iyer B. R. Srinivasa T. Bergfors T. Unge S. L. Mowbray M. Larhed T. A. Jones A. Karlen J. Med. Chem. 2011 54 4964 4976
- (2011) J. Med. Chem. , vol.54 , pp. 4964-4976
- Andaloussi, M.¹ Henriksson, L.M.² Wieckowska, A.³ Lindh, M.⁴ Bjorkelid, C.⁵ Larsson, A.M.⁶ Suresh, S.⁷ Iyer, H.⁸ Srinivasa, B.R.⁹ Bergfors, T.¹⁰ Unge, T.¹¹ Mowbray, S.L.¹² Larhed, M.¹³ Jones, T.A.¹⁴ Karlen, A.¹⁵

20
- 79960155208
- L. Deng J. Diao P. Chen V. Pujari Y. Yao G. Cheng D. C. Crick B. V. Prasad Y. Song J. Med. Chem. 2011 54 4721 4734
- (2011) J. Med. Chem. , vol.54 , pp. 4721-4734
- Deng, L.¹ Diao, J.² Chen, P.³ Pujari, V.⁴ Yao, Y.⁵ Cheng, G.⁶ Crick, D.C.⁷ Prasad, B.V.⁸ Song, Y.⁹

21
- 34248532764
- V. Devreux J. Wiesner H. Jomaa J. Rozenski J. Van der Eycken S. Van Calenbergh J. Org. Chem. 2007 72 3783 3789
- (2007) J. Org. Chem. , vol.72 , pp. 3783-3789
- Devreux, V.¹ Wiesner, J.² Jomaa, H.³ Rozenski, J.⁴ Van Der Eycken, J.⁵ Van Calenbergh, S.⁶

22
- 34547550120
- V. Devreux J. Wiesner H. Jomaa J. Van der Eycken S. Van Calenbergh Bioorg. Med. Chem. Lett. 2007 17 4920 4923
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 4920-4923
- Devreux, V.¹ Wiesner, J.² Jomaa, H.³ Van Der Eycken, J.⁴ Van Calenbergh, S.⁵

23
- 33144477580
- T. Haemers J. Wiesner S. Van Poecke J. Goeman D. Henschker E. Beck H. Jomaa S. Van Calenbergh Bioorg. Med. Chem. Lett. 2006 16 1888 1891
- (2006) Bioorg. Med. Chem. Lett. , vol.16 , pp. 1888-1891
- Haemers, T.¹ Wiesner, J.² Van Poecke, S.³ Goeman, J.⁴ Henschker, D.⁵ Beck, E.⁶ Jomaa, H.⁷ Van Calenbergh, S.⁸

24
- 37349048178
- T. Kurz C. Behrendt M. Pein U. Kaula B. Bergmann R. D. Walter Arch. Pharm. 2007 340 661 666
- (2007) Arch. Pharm. , vol.340 , pp. 661-666
- Kurz, T.¹ Behrendt, C.² Pein, M.³ Kaula, U.⁴ Bergmann, B.⁵ Walter, R.D.⁶

25
- 34547161878
- T. Kurz K. Schluter M. Pein C. Behrendt B. Bergmann R. D. Walter Arch. Pharm. 2007 340 339 344
- (2007) Arch. Pharm. , vol.340 , pp. 339-344
- Kurz, T.¹ Schluter, K.² Pein, M.³ Behrendt, C.⁴ Bergmann, B.⁵ Walter, R.D.⁶

26
- 34748895608
- R. Ortmann J. Wiesner K. Silber G. Klebe H. Jomaa M. Schlitzer Arch. Pharm. 2007 340 483 490
- (2007) Arch. Pharm. , vol.340 , pp. 483-490
- Ortmann, R.¹ Wiesner, J.² Silber, K.³ Klebe, G.⁴ Jomaa, H.⁵ Schlitzer, M.⁶

27
- 77954734834
- T. Verbrugghen P. Cos L. Maes S. Van Calenbergh J. Med. Chem. 2010 53 5342 5346
- (2010) J. Med. Chem. , vol.53 , pp. 5342-5346
- Verbrugghen, T.¹ Cos, P.² Maes, L.³ Van Calenbergh, S.⁴

28
- 34447623874
- L. M. Henriksson T. Unge J. Carlsson J. Aqvist S. L. Mowbray T. A. Jones J. Biol. Chem. 2007 282 19905 19916
- (2007) J. Biol. Chem. , vol.282 , pp. 19905-19916
- Henriksson, L.M.¹ Unge, T.² Carlsson, J.³ Aqvist, J.⁴ Mowbray, S.L.⁵ Jones, T.A.⁶

29
- 9644301008
- A. Mac Sweeney R. Lange R. P. Fernandes H. Schulz G. E. Dale A. Douangamath P. J. Proteau C. Oefner J. Mol. Biol. 2005 345 115 127
- (2005) J. Mol. Biol. , vol.345 , pp. 115-127
- Mac Sweeney, A.¹ Lange, R.² Fernandes, R.P.³ Schulz, H.⁴ Dale, G.E.⁵ Douangamath, A.⁶ Proteau, P.J.⁷ Oefner, C.⁸

30
- 80051925129
- M. Andaloussi M. Lindh C. Bjorkelid S. Suresh A. Wieckowska H. Iyer A. Karlen M. Larhed Bioorg. Med. Chem. Lett. 2011 21 5403 5407
- (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 5403-5407
- Andaloussi, M.¹ Lindh, M.² Bjorkelid, C.³ Suresh, S.⁴ Wieckowska, A.⁵ Iyer, H.⁶ Karlen, A.⁷ Larhed, M.⁸

31
- 79551481493
- T. Bodill A. C. Conibear G. L. Blatch K. A. Lobb P. T. Kaye Bioorg. Med. Chem. Lett. 2011 19 1321 1327
- (2011) Bioorg. Med. Chem. Lett. , vol.19 , pp. 1321-1327
- Bodill, T.¹ Conibear, A.C.² Blatch, G.L.³ Lobb, K.A.⁴ Kaye, P.T.⁵

32
- 71049170515
- L. Deng S. Sundriyal V. Rubio Z. Z. Shi Y. Song J. Med. Chem. 2009 52 6539 6542
- (2009) J. Med. Chem. , vol.52 , pp. 6539-6542
- Deng, L.¹ Sundriyal, S.² Rubio, V.³ Shi, Z.Z.⁴ Song, Y.⁵

33
- 45549085673
- D. Giessmann P. Heidler T. Haemers S. Van Calenbergh A. Reichenberg H. Jomaa C. Weidemeyer S. Sanderbrand J. Wiesner A. Link Chem. Biodiversity 2008 5 643 656
- (2008) Chem. Biodiversity , vol.5 , pp. 643-656
- Giessmann, D.¹ Heidler, P.² Haemers, T.³ Van Calenbergh, S.⁴ Reichenberg, A.⁵ Jomaa, H.⁶ Weidemeyer, C.⁷ Sanderbrand, S.⁸ Wiesner, J.⁹ Link, A.¹⁰

34
- 84873820710
- A. K. Patel Int. J. Pharma Bio Sci. 2012 3 72 91
- (2012) Int. J. Pharma Bio Sci. , vol.3 , pp. 72-91
- Patel, A.K.¹

35
- 18744377281
- K. Silber P. Heidler T. Kurz G. Klebe J. Med. Chem. 2005 48 3547 3563
- (2005) J. Med. Chem. , vol.48 , pp. 3547-3563
- Silber, K.¹ Heidler, P.² Kurz, T.³ Klebe, G.⁴

36
- 4544384632
- C. J. Marmion D. Griffith K. B. Nolan Eur. J. Inorg. Chem. 2004 15 3003 3016
- (2004) Eur. J. Inorg. Chem. , vol.15 , pp. 3003-3016
- Marmion, C.J.¹ Griffith, D.² Nolan, K.B.³

37
- 0032237257
- D. Villemin F. Simeon H. Decreus P.-A. Jaffres Phosphorus, Sulfur Silicon Relat. Elem. 1998 133 209 213
- (1998) Phosphorus, Sulfur Silicon Relat. Elem. , vol.133 , pp. 209-213
- Villemin, D.¹ Simeon, F.² Decreus, H.³ Jaffres, P.-A.⁴

38
- 0012302031
- P. D. M. Puyau J. J. Perie Phosphorus, Sulfur Silicon Relat. Elem. 1996 112 71 90
- (1996) Phosphorus, Sulfur Silicon Relat. Elem. , vol.112 , pp. 71-90
- Puyau, P.D.M.¹ Perie, J.J.²

39
- 77952475238
- C. Zingle L. Kuntz D. Tritsch C. Grosdemange-Billiard M. Rohmer J. Org. Chem. 2010 75 3203 3207
- (2010) J. Org. Chem. , vol.75 , pp. 3203-3207
- Zingle, C.¹ Kuntz, L.² Tritsch, D.³ Grosdemange-Billiard, C.⁴ Rohmer, M.⁵

40
- 77954043138
- S. Jawaid H. Seidle W. Zhou H. Abdirahman M. Abadeer J. H. Hix M. L. van Hoek R. D. Couch PLoS One 2009 4 e8288
- (2009) PLoS One , vol.4 , pp. 8288
- Jawaid, S.¹ Seidle, H.² Zhou, W.³ Abdirahman, H.⁴ Abadeer, M.⁵ Hix, J.H.⁶ Van Hoek, M.L.⁷ Couch, R.D.⁸

41
- 79958275846
- A. Tsang H. Seidle S. Jawaid W. Zhou C. Smith R. D. Couch PLoS One 2011 6 e20884
- (2011) PLoS One , vol.6 , pp. 20884
- Tsang, A.¹ Seidle, H.² Jawaid, S.³ Zhou, W.⁴ Smith, C.⁵ Couch, R.D.⁶

42
- 0037039285
- A. T. Koppisch D. T. Fox B. S. Blagg C. D. Poulter Biochemistry 2002 41 236 243
- (2002) Biochemistry , vol.41 , pp. 236-243
- Koppisch, A.T.¹ Fox, D.T.² Blagg, B.S.³ Poulter, C.D.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.