Puerarin attenuates neuronal degeneration in the substantia nigra of 6-OHDA-lesioned rats through regulating BDNF expression and activating the Nrf2/ARE signaling pathway

Brain Research

Volumn 1523, Issue , 2013, Pages 1-9

  Li, Rong ^a   Liang, Tao ^c   Xu, Lingyuan ^b   Zheng, Ni ^c   Zhang, Kefeng ^c   Duan, Xiaoqun ^a  

^a GUILIN MEDICAL UNIVERSITY   (China)

^b Youjiang Medical University for Nationalities   (China)

^c GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

BDNF; Nrf2 ARE signaling pathway; Oxidative stress; Parkinson's disease; Puerarin; Substantia nigra

Indexed keywords

APOMORPHINE; BRAIN DERIVED NEUROTROPHIC FACTOR; CATALASE; CYTOCHROME C OXIDASE; DOPAMINE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MESSENGER RNA; OXIDOPAMINE; PUERARIN; TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CHEMICAL STRUCTURE; CONTROLLED STUDY; HISTOPATHOLOGY; NERVE CELL DEGENERATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SUBSTANTIA NIGRA; UPREGULATION;

BDNF; NRF2/ARE SIGNALING PATHWAY; OXIDATIVE STRESS; PARKINSON'S DISEASE; PUERARIN; SUBSTANTIA NIGRA;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CATALASE; DOPAMINE; ELECTRON TRANSPORT COMPLEX IV; GA-BINDING PROTEIN TRANSCRIPTION FACTOR; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HYDROXYDOPAMINES; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOFLAVONES; MALE; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA; SYMPATHOLYTICS;

PARKINSONIA; RATTUS;

EID: 84879842266     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.05.046     Document Type: Article

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