Urotropine-bromine promoted synthesis of functionalized oxaspirotricyclic furopyrimidines via a domino Knoevenagel condensation/Michael addition/α-bromination/Williamson cycloetherification sequence in water

Tetrahedron

Volumn 69, Issue 33, 2013, Pages 6804-6809

  Teimouri, Mohammad Bagher ^a   Akbari Moghaddam, Peyman ^b   Motaghinezhad, Mahnaz ^c  

^a KHARAZMI UNIVERSITY   (Iran)

^b CHEMISTRY AND CHEMICAL ENGINEERING RESEARCH CENTER OF IRAN   (Iran)

^c ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Benzaldehydes; Spiro compound; Thiobarbituric acids; Urotropine bromine

Indexed keywords

5 (2 CHLOROPHENYL) 2,2' DITHIOXO 1,5 DIHYDRO 2H,2'H SPIRO(FURO[2,3 D]PYRIMIDINE 6,5' PYRIMIDINE) 4,4',6'(1'H,3H,3'H)TRIONE; 5 (3 HYDROXYPHENYL) 1,5 DIHYDRO 2H,2'H SPIRO(FURO[2,3 D]PYRIMIDINE 6,5' PYRIMIDINE) 2,2',4,4',6'(1'H,3H,3'H)PENTONE; 5 (4 BROMOPHENYL) 1,5 DIHYDRO 2H,2'H SPIRO(FURO[2,3 D]PYRIMIDINE 6,5' PYRIMIDINE) 2,2',4,4',6'(1'H,3H,3'H)PENTONE; 5 (4 CHLOROPHENYL) 1,5 DIHYDRO 2H,2'H SPIRO(FURO[2,3 D]PYRIMIDINE 6,5' PYRIMIDINE) 2,2',4,4',6'(1'H,3H,3'H)PENTONE; 5 (4 CHLOROPHENYL) 2,2' DITHIOXO 1,5 DIHYDRO 2H,2'H SPIRO(FURO[2,3 D]PYRIMIDINE 6,5' PYRIMIDINE) 4,4',6'(1'H,3H,3'H)TRIONE; 5 (4 FLUOROPHENYL) 1,5 DIHYDRO 2H,2'H SPIRO(FURO[2,3 D]PYRIMIDINE 6,5' PYRIMIDINE) 2,2',4,4',6'(1'H,3H,3'H)PENTONE; 5 (4 NITROPHENYL) 1,5 DIHYDRO 2H,2'H SPIRO(FURO[2,3 D]PYRIMIDINE 6,5' PYRIMIDINE) 2,2',4,4',6'(1'H,3H,3'H)PENTONE; 5 (4 NITROPHENYL) 2,2' DITHIOXO 1,5 DIHYDRO 2H,2'H SPIRO(FURO[2,3 D]PYRIMIDINE 6,5' PYRIMIDINE) 4,4',6'(1'H,3H,3'H)TRIONE; 5 PHENYL 1,5 DIHYDRO 2H,2'H SPIRO(FURO[2,3 D]PYRIMIDINE 6,5' PYRIMIDINE) 2,2',4,4',6'(1'H,3H,3'H)PENTONE; ALDEHYDE; BROMINE; PYRIMIDINE; SPIRO[FURO[2,3 D]PYRIMIDINE 6,5' PYRIMIDINE] DERIVATIVE; THIOBARBITURIC ACID; TROPINE; UNCLASSIFIED DRUG; UROTROPINE; WATER;

ARTICLE; BROMINATION; CATALYSIS; CHEMICAL REACTION; KNOEVENAGEL CONDENSATION; MICHAEL ADDITION; PRIORITY JOURNAL; ROOM TEMPERATURE; WILLIAMSON CYCLOETHERIFICATION;

EID: 84879841804     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2013.06.030     Document Type: Article

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