Structural insights into the functions of TBK1 in innate antimicrobial immunity

Structure

Volumn 21, Issue 7, 2013, Pages 1137-1148

  Shu, Chang ^a   Sankaran, Banumathi ^b   Chaton, Catherine T ^c   Herr, Andrew B ^c   Mishra, Ashutosh ^d   Peng, Junmin ^d   Li, Pingwei ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; DIMER; I KAPPA B KINASE; INTERFERON REGULATORY FACTOR 3; MONOMER; PROTEIN SERINE THREONINE KINASE; SCAFFOLD PROTEIN; SUMO PROTEIN; TBK1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; GENETIC TRANSCRIPTION; HUMAN; INNATE IMMUNITY; MICROBIAL IMMUNITY; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL INFECTIONS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; HUMANS; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMMUNITY, INNATE; INDOLES; INTERFERON REGULATORY FACTOR-3; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN KINASE INHIBITORS; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN-SERINE-THREONINE KINASES; PYRROLES; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 84879841532     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2013.04.025     Document Type: Article

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