Hit identification of IKKβ natural product inhibitor

BMC Pharmacology and Toxicology

Volumn 14, Issue , 2013, Pages

  Leung, Chung Hang ^a   Chan, Daniel Shiu Hin ^b   Li, Ying Wei ^b   Fong, Wang Fun ^b   Ma, Dik Lung ^b  

^a University of Macau   (Macao)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOIC ACID DERIVATIVE; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NATURAL PRODUCT; TUMOR NECROSIS FACTOR ALPHA; BIOLOGICAL PRODUCT; I KAPPA B; I KAPPA B KINASE; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA;

ARTICLE; BINDING SITE; CELL STRAIN HEPG2; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG IDENTIFICATION; DRUG SCREENING; ENZYME ACTIVITY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATORY DISEASE; MOLECULAR DOCKING; NEOPLASM; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; CHEMISTRY; DRUG ANTAGONISM; MOLECULAR LIBRARY;

BENZOATES; BIOLOGICAL AGENTS; HEP G2 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; I-KAPPA B KINASE; I-KAPPA B PROTEINS; MOLECULAR DOCKING SIMULATION; NF-KAPPA B; SMALL MOLECULE LIBRARIES; TUMOR NECROSIS FACTOR-ALPHA;

MLCS; MLOWN;

EID: 84879823774     PISSN: 20506511     EISSN: None     Source Type: Journal    
DOI: 10.1186/2050-6511-14-3     Document Type: Article

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