Molecular weight-dependent genetic information transfer with disulfide-linked polyethylenimine-based nonviral vectors

Journal of Biomaterials Applications

Volumn 28, Issue 1, 2013, Pages 112-124

  Parhiz, Hamideh ^a   Hashemi, Maryam ^a   Hatefi, Arash ^b   Shier, Wayne Thomas ^c   Farzad, Sara Amel ^a   Ramezani, Mohammad ^a  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b RUTGERS UNIVERSITY   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Gene therapy; histone H1 C terminal tail; nuclear localization signal; polyethylenimine; siRNA

Indexed keywords

C-TERMINAL TAIL; HIGH MOLECULAR WEIGHT; LUCIFERASE EXPRESSION; NUCLEAR LOCALIZATION SIGNAL; POLYETHYLENIMINES; SIRNA; SMALL INTERFERING RNA; TRANSFECTION EFFICIENCY;

GENE THERAPY; GENES; MOLECULAR WEIGHT; NUCLEIC ACIDS; SULFUR COMPOUNDS;

MOLECULAR BIOLOGY;

ENHANCED GREEN FLUORESCENT PROTEIN; HISTONE H1; LUCIFERASE; PLASMID DNA; POLYETHYLENEIMINE; SMALL INTERFERING RNA; VIRUS LARGE T ANTIGEN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DISULFIDE BOND; HEMOLYSIS; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUCLEAR LOCALIZATION SIGNAL; PARTICLE SIZE; POLYMERIZATION; ZETA POTENTIAL;

GENE THERAPY; HISTONE H1 C-TERMINAL TAIL; NUCLEAR LOCALIZATION SIGNAL; POLYETHYLENIMINE; SIRNA;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELL LINE; DISULFIDES; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; LUCIFERASES; MATERIALS TESTING; MICE; MOLECULAR WEIGHT; NUCLEAR LOCALIZATION SIGNALS; POLYETHYLENEIMINE; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84879767553     PISSN: 08853282     EISSN: 15308022     Source Type: Journal    
DOI: 10.1177/0885328212440344     Document Type: Article

References (49)

1. Han S, Mahato RI, Sung YK, Kim SW. Development of biomaterials for gene therapy. Mol Ther. 2000 ; 2: 302-317
2. Brown MD, Schatzlein AG, Uchegbu IF. Gene delivery with synthetic (non viral) carriers. Int J Pharm. 2001 ; 229: 1-21
3. Park TG, Jeong JH, Kim SW. Current status of polymeric gene delivery systems. Adv Drug Deliv Rev. 2006 ; 58: 467-486
4. Kim TI, Ou M, Lee M, Kim SW. Arginine-grafted bioreducible poly(disulfide amine) for gene delivery systems. Biomaterials. 2009 ; 30: 658-664
5. Forrest ML, Meister GE, Koerber JT, et al. Partial acetylation of polyethylenimine enhances in vitro gene delivery. Pharm Res. 2004 ; 21: 365-371
6. Neu M, Fischer D, Kissel T. Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives. J Gene Med. 2005 ; 7: 992-1009
7. Demeneix B, Behr J, Boussif O, et al. Gene transfer with lipospermines and polyethylenimines. Adv Drug Deliv Rev. 1998 ; 30: 85-95
8. Thomas M, Klibanov AM. Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells. Proc Natl Acad Sci USA. 2002 ; 99: 14640-14645
9. Gabrielson NP, Pack DW. Acetylation of polyethylenimine enhances gene delivery via weakened polymer/DNA interactions. Biomacromolecules. 2006 ; 7: 2427-2435
10. Dehshahri A, Oskuee RK, Shier WT, et al. Gene transfer efficiency of high primary amine content, hydrophobic, alkyl-oligoamine derivatives of polyethylenimine. Biomaterials. 2009 ; 30: 4187-4194
11. Shen Y, Peng H, Deng J, et al. High mobility group box 1 protein enhances polyethylenimine mediated gene delivery in vitro. Int J Pharm. 2009 ; 375: 140-147
12. Kircheis R, Kichler A, Wallner G, et al. Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery. Gene Ther. 1997 ; 4: 409-418
13. Erbacher P, Remy JS, Behr JP. Gene transfer with synthetic virus-like particles via the integrin-mediated endocytosis pathway. Gene Ther. 1999 ; 6: 138-145
14. Zanta MA, Boussif O, Adib A, et al. In vitro gene delivery to hepatocytes with galactosylated polyethylenimine. Bioconjug Chem. 1997 ; 8: 839-844
15. Park IK, Lasiene J, Chou SH, et al. Neuron-specific delivery of nucleic acids mediated by Tet1-modified poly(ethylenimine). J Gene Med. 2007 ; 9: 691-702
16. Kursa M, Walker GF, Roessler V, et al. Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer. Bioconjug Chem. 2003 ; 14: 222-231
17. Li D, Wang QQ, Tang GP, et al. Receptor-mediated gene delivery using polyethylenimine (PEI) coupled with polypeptides targeting FGF receptors on cells surface. J Zhejiang Univ Sci B. 2006 ; 7: 906-911
18. Gabrielson NP, Pack DW. Efficient polyethylenimine-mediated gene delivery proceeds via a caveolar pathway in HeLa cells. J Control Release. 2009 ; 136: 54-61
19. Kwon EJ, Bergen JM, Park IK, et al. Peptide-modified vectors for nucleic acid delivery to neurons. J Control Release. 2008 ; 132: 230-235
20. Tachibana R, Harashima H, Shinohara Y, et al. Quantitative studies on the nuclear transport of plasmid DNA and gene expression employing nonviral vectors. Adv Drug Deliv Rev. 2001 ; 52: 219-226
21. Cartier R, Reszka R. Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems. Gene Ther. 2002 ; 9: 157-167
22. Kaouass M, Beaulieu R, Balicki D. Histonefection: novel and potent non-viral gene delivery. J Control Release. 2006 ; 113: 245-254
23. Zanta MA, Belguise-Valladier P, Behr JP. Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci USA. 1999 ; 96: 91-96
24. Eguchi A, Furusawa H, Yamamoto A, et al. Optimization of nuclear localization signal for nuclear transport of DNA-encapsulating particles. J Control Release. 2005 ; 104: 507-519
25. Aris A, Villaverde A. Engineering nuclear localization signals in modular protein vehicles for gene therapy. Biochem Biophys Res Commun. 2003 ; 304: 625-631
26. Baake M, Doenecke D, Albig W. Characterisation of nuclear localisation signals of the four human core histones. J Cell Biochem. 2001 ; 81: 333-346
27. Hagstrom JE, Sebestyen MG, Budker V, et al. Complexes of non-cationic liposomes and histone H1 mediate efficient transfection of DNA without encapsulation. Biochim Biophys Acta. 1996 ; 1284: 47-55
28. Bottger M, Zaitsev SV, Otto A, et al. Acid nuclear extracts as mediators of gene transfer and expression. Biochim Biophys Acta. 1998 ; 1395: 78-87
29. Khadake JR, Rao MR. Condensation of DNA and chromatin by an SPKK-containing octapeptide repeat motif present in the C-terminus of histone H1. Biochemistry. 1997 ; 36: 1041-1051
30. Moran F, Montero F, Azorin F, et al. Condensation of DNA by the C-terminal domain of histone H1. A circular dichroism study. Biophys Chem. 1985 ; 22: 125-129
31. Puebla I, Esseghir S, Mortlock A, et al. A recombinant H1 histone-based system for efficient delivery of nucleic acids. J Biotechnol. 2003 ; 105: 215-226
32. Tang MX, Szoka FC. The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther. 1997 ; 4: 823-832
33. Bloomfield VA. Condensation of DNA by multivalent cations: considerations on mechanism. Biopolymers. 1991 ; 31: 1471-1481
34. Macrae IJ, Zhou K, Li F, et al. Structural basis for double-stranded RNA processing by Dicer. Science. 2006 ; 311: 195-198
35. Snyder SL, Sobocinski PZ. An improved 2,4,6-trinitrobenzenesulfonic acid method for the determination of amines. Anal Biochem. 1975 ; 64: 284-288
36. Boeckle S, Fahrmeir J, Roedl W, et al. Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes. J Control Release. 2006 ; 112: 240-248
37. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983 ; 65: 55-63
38. Panyam J, Labhasetwar V. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev. 2003 ; 55: 329-347
39. Khalil IA, Kogure K, Akita H, et al. Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery. Pharmacol Rev. 2006 ; 58: 32-45
40. Oskuee RK, Dehshahri A, Shier WT, et al. Alkylcarboxylate grafting to polyethylenimine: a simple approach to producing a DNA nanocarrier with low toxicity. J Gene Med. 2009 ; 11: 921-932
41. Branden LJ, Mohamed AJ, Smith CI. A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA. Nat Biotechnol. 1999 ; 17: 784-787
42. Nigg EA. Nucleocytoplasmic transport: signals, mechanisms and regulation. Nature. 1997 ; 386: 779-787
43. Bauerle M, Doenecke D, Albig W. The requirement of H1 histones for a heterodimeric nuclear import receptor. J Biol Chem. 2002 ; 277: 32480-32489
44. Carlisle RC, Bettinger T, Ogris M, et al. Adenovirus hexon protein enhances nuclear delivery and increases transgene expression of polyethylenimine/plasmid DNA vectors. Mol Ther. 2001 ; 4: 473-483
45. Bellomo G, Vairetti M, Stivala L, et al. Demonstration of nuclear compartmentalization of glutathione in hepatocytes. Proc Natl Acad Sci USA. 1992 ; 89: 4412-4416
46. Urban-Klein B, Werth S, Abuharbeid S, et al. RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo. Gene Ther. 2005 ; 12: 461-466
47. Read ML, Singh S, Ahmed Z, et al. A versatile reducible polycation-based system for efficient delivery of a broad range of nucleic acids. Nucleic Acids Res. 2005 ; 33: e86 - e86
48. Hassani Z, Lemkine GF, Erbacher P, et al. Lipid-mediated siRNA delivery down-regulates exogenous gene expression in the mouse brain at picomolar levels. J Gene Med. 2005 ; 7: 198-207
49. Grayson AC, Doody AM, Putnam D. Biophysical and structural characterization of polyethylenimine-mediated siRNA delivery in vitro. Pharm Res. 2006 ; 23: 1868-1876