A genome-wide RNAi screen reveals that mRNA decapping restricts bunyaviral replication by limiting the pools of dcp2-accessible targets for cap-snatching

Genes and Development

Volumn 27, Issue 13, 2013, Pages 1511-1525

  Hopkins, Kaycie C ^a   McLane, Laura M ^a   Maqbool, Tariq ^a   Panda, Debasis ^a   Gordesky Gold, Beth ^a   Cherry, Sara ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Bunyavirus; Cap snatching; Dcp2; RNA decapping; RNAi screen; RVFV

Indexed keywords

DCP2 PROTEIN; HOST FACTOR; MESSENGER RNA; PROTEIN; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; CELL CYCLE; DIPLORNA VIRUS; DIPTERA; DROSOPHILA; GENETIC ASSOCIATION; IMMUNOFLUORESCENCE; INSECT CELL; NONHUMAN; PRIORITY JOURNAL; RIFT VALLEY FEVER BUNYAVIRUS; RNA ANALYSIS; RNA STABILITY; VIRUS INFECTION; VIRUS REPLICATION;

BUNYAVIRUS; CAP-SNATCHING; DCP2; RNA DECAPPING; RNAI SCREEN; RVFV;

AEDES; ANIMALS; CELL CYCLE CHECKPOINTS; CELL LINE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; GENOME, INSECT; ORTHOBUNYAVIRUS; RNA CAPS; RNA INTERFERENCE; RNA, MESSENGER; TRANSCRIPTION FACTORS; VIRUS REPLICATION;

HEXAPODA; MAMMALIA; ORTHOBUNYAVIRUS; RIFT VALLEY FEVER VIRUS;

EID: 84879741542     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.215384.113     Document Type: Article

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