Suppression of SHP-1 promotes corticospinal tract sprouting and functional recovery after brain injury

Cell Death and Disease

Volumn 4, Issue 4, 2013, Pages

  Tanaka, T ^a,b   Fujita, Y ^a,b   Ueno, M ^a,b   Shultz, L D ^c   Yamashita, T ^a,b  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c JACKSON LABORATORY   (United States)

Author keywords

Axonal sprouting; Brain injury; Corticospinal tract; Functional recovery; SHP 1

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE SHP 1; ENZYME INHIBITOR; NSC 87877; NSC-87877; PTPN6 PROTEIN, MOUSE; QUINOLINE DERIVATIVE; NEURON SPECIFIC NUCLEAR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; CERVICAL SPINAL CORD; CONTROLLED STUDY; CONVALESCENCE; DOWN REGULATION; ENZYME ACTIVITY; FORELIMB; GROWTH INHIBITION; MOTOR PERFORMANCE; MOUSE; NERVE CELL NETWORK; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL TRACT; WILD TYPE; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HETEROZYGOTE; INJURY; MALE; METABOLISM; MOTOR CORTEX; NERVE REGENERATION; PHYSIOLOGY; ANIMAL TISSUE; BEHAVIOR; BRAIN NERVE CELL; DENERVATION; NERVE FIBER GROWTH; REAL TIME POLYMERASE CHAIN REACTION; SENSORIMOTOR CORTEX;

MUS;

ANIMALS; AXONS; BRAIN INJURIES; DOWN-REGULATION; ENZYME INHIBITORS; FORELIMB; HETEROZYGOTE; MALE; MICE; MOTOR CORTEX; NERVE FIBERS; NERVE REGENERATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; PYRAMIDAL TRACTS; QUINOLINES; RECOVERY OF FUNCTION;

EID: 84879703878     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.102     Document Type: Article

References (42)

1. Alpert JS, Thygesen K, Antman E, Bassand JP. Myocardial infarction redefined -A consensus document of the joint European society of cardiology/American College of cardiology committee for the redefinition of myocardial infarction. J Am Coll Cardiol 2000; 36: 959-969
2. Choudhary R, Mishra KP, Subramanyam C. Prevention of isoproterenol induced cardiac hypertrophy by eugenol. Indian J Clin Biochem 2006; 21: 107-113
3. Chatterjee A, Mir SA, Dutta D, Mitra A, Pathak K, Sarkar S. Analysis of p53 and NF-kB signaling in modulating the cardiomyocyte fate during hypertrophy. J Cell Physiol 2010; 226: 2543-2554
4. Garciarena CD, Caldiz CI, Portiansky EL, Chiappe de Cingolani GE, Ennis IL. Chronic NHE-1 blockade induces an antiapoptotic effect in the hypertrophied heart. J Appl Physiol 2009; 106: 1325-1331
5. Choudhury S, Bae S, Kumar SR, Ke Q, Yalamarti B, Choi JH et al. Role of AIF in cardiac apoptosis in hypertrophic cardiomyocytes from Dahl salt-sensitive rats. Cardiovasc Res 2010; 85: 28-37
6. Sarkar S, Chawla-Sarkar M, Young D, Nishiyama K, Rayborn ME, Hollyfield JG et al. myocardial cell death and regeneration during progression of cardiac hypertrophy to heart failure. J Biol Chem 2004; 279: 52630-52642
7. Griffiths ER, Friehs I, Scherr E, Poutias D, McGowan FX, del Nido PJ. Electron transport chain dysfunction in neonatal pressure-overload hypertrophy precedes cardiomyocyte apoptosis independent of oxidative stress. J Thorac Cardiovasc Surg 2010; 139: 1609-1617
8. Xie MJ, Chang H, Wang YY, Zhang L, Song Z, Guo WG et al. Evidence that apoptotic signalling in hypertrophic cardiomyocytes is determined by mitochondrial pathways involving protein kinase Cd. Clin Exp Pharmacol Physiol 2010; 37: 1120-1128
9. Bloom S, Davis DL. Calcium as mediator of isoproterenol-Induced myocardial necrosis. Am J Pathol 1972; 69: 459-470
10. von Harsdorf R, Li PF, Dietz R. Signaling Pathways in Reactive Oxygen Species-Induced Cardiomyocyte apoptosis. Circulation 1999; 99: 2934-2941
11. Zhang GM, Su SP, Wang Y, Li TD, Li XY, Tan H et al. Effect of ischemic postconditioning on activation of p38 mitogen activated protein kinase and cardiocyte apoptosis in rats. Acta Acad Med Sin 2010; 32: 526-532
12. Sun HJ, Li H, Zou Z, Shi XY. Protective effects of hydroxyethyl starch 130/0.4 against myocardial ischemia/reperfusion injury in rats. Chin Med J 2011; 124: 291-297
13. Morrison LE, Whittaker RJ, Klepper RE, Wawrousek EF, Glembotski CC. Roles for alphaB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusioninduced damage in a KO mouse model. Am J Physiol Heart Circ Physiol 2004; 286: H847-H855
14. Bullard B, Ferguson C, Minajeva A, Leake MC, Gautel M, Labeit D et al. Association of the chaperone alphaB-crystallin with titin in heart muscle. J Biol Chem 2004; 279: 7917-7924
15. Maloyan A, Sanbe A, Osinska H, Westfall M, Robinson D, Imahashi K et al. Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desminrelated cardiomyopathy. Circulation 2005; 112: 3451-3461
16. Rajasekaran NS, Connell P, Christians ES, Yan LJ, Taylor RP, Orosz A et al. Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice. Cell 2007; 130: 427-439
17. Jin JK, Whittaker R, Glassy MS, Barlow SB, Gottlieb RA, Glembotski CC. Localization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion. Am J Physiol Heart Circ Physiol 2008; 294: H337-H344
18. Baldus S, Mü llerleile K, Chumley P, Steven D, Rudolph V, Lund GK et al. Inhibition of xanthine oxidase improves myocardial contractility in patients with ischemic cardiomyopathy. Free Radic Biol Med 2006; 41: 1282-1288
19. Kondo T, Ogawa Y, Sugiyama S, Ito T, Satake T, Ozawa T. Mechanism of isoproterenol induced myocardial damage. Cardiovasc Res 1987; 21: 248-254
20. Lim DS, Roberts R, Marian AJ. Expression profiling of cardiac genes in human hypertrophic cardiomyopathy: Insight into the pathogenesis of phenotypes. J Am Coll Cardiol 2001; 38: 1175-1180
21. Shimizu S, Narita M, Tsujimoto Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 1999; 399: 483-487
22. Zheng Y, Shi Y, Tian C, Jiang C, Jin H, Chen J et al. Essential role of the voltagedependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide. Oncogene 2004; 23: 1239-1247
23. Glembotski CC. Endoplasmic reticulum stress in the heart. Circ Res 2007; 101: 975-984
24. Okada K, Minamino T, Tsukamoto Y, Liao Y, Tsukamoto O, Takashima S et al. Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: Possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis. Circulation 2004; 110: 705-712
25. Sari FR, Watanabe K, Widyantoro B, Thandavarayan RA, Harima M, Zhang S et al. Partial inactivation of cardiac 14-3-3 protein in vivo elicits endoplasmic reticulum stress (ERS) and activates ERS-Initiated apoptosis in ERS-Induced mice. Cell Physiol Biochem 2010; 26: 167-178
26. Zhang C, Kawauchi J, Adachi MT, Hashimoto Y, Oshiro S, Aso T et al. Activation of JNK and transcriptional repressor ATF3/LRF1 through the IRE1/TRAF2 pathway is implicated in human vascular endothelial cell death by homocysteine. Biochem Biophys Res Commun 2001; 289: 718-724
27. Pfahl M, Piedrafita FJ. Retinoid targets for apoptosis induction. Oncogene 2003; 22: 9058-9062
28. Bredesen DE, Rao RV, Mehlen P. Cell death in the nervous system. Nature 2006; 443: 796-802
29. Thuerauf DJ, Marcinko M, Gude N, Rubio M, Sussman MA, Glembotski CC. Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes. Circ Res 2006; 99: 275-282
30. Lee YY, Hong SH, Lee YJ, Chung SS, Jung HS, Park SG et al. Tauroursodeoxycholate (TUDCA), chemical chaperone, enhances function of islets by reducing ER stress. Biochem Biophys Res Commun 2010; 397: 735-739
31. Chis R, Sharma P, Bousette N, Miyake T, Wilson A, Backx PH et al. a Crystallin B prevents apoptosis following H2O2 exposure in mouse neonatal cardiomyocytes. Am J Physiol Heart Circ Physiol 2012; 303: H967-H978
32. Ruan Q, Han S, Jiang WG, Boulton ME, Chen ZJ, Law BK et al. aB-crystallin, an effector of unfolded protein response, confers anti-VEGF resistance to breast cancer via maintenance of intracrine VEGF in endothelial cells. Mol Cancer Res 2011; 9: 1632-1643
33. Korkmaz S, Radovits T, Barnucz E, Hirschberg K, Neugebauer P, Loganathan S et al. Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury. Circulation 2009; 120: 677-686
34. Pfeffer MA, Pfeffer JM, Fishbein MC, Fletcher PJ, Spadaro J, Kloner RA et al. Myocardial infarct size and ventricular function in rats. Circ Res 1979; 44: 503-512
35. Bohl S, Medway DJ, Schulz-Menger J, Schneider JE, Neubauer S, Lygate CA. Refined approach for quantification of in vivo ischemia-reperfusion injury in the mouse heart. Am J Physiol Heart Circ Physiol 2009; 297: H2054-H2058
36. Rivard AL, Steer CJ, Kren BT, Rodrigues CM, Castro RE, Bianco RW et al. Administration of tauroursodeoxycholic acid (TUDCA) reduces apoptosis following myocardial infarction in rat. Am J Chin Med 2007; 35: 279-295
37. Pathak M, Sarkar S, Vellaichamy E, Sen S. Role of myocytes in myocardial collagen production. Hypertension 2001; 37: 833-840
38. Shang L, Ananthakrishnan R, Li Q, Quadri N, Abdillahi M, Zhu Z et al. RAGE modulates hypoxia/reoxygenation injury in adult murine cardiomyocytes via JNK and GSK-3beta signaling pathways. PLoS One 2010; 5: E10092
39. Bhowmick R, Halder UC, Chattopadhyay S, Chanda S, Nandi S, Bagchi P et al. Rotaviral enterotoxin nonstructural protein 4 targets mitochondria for activation of apoptosis during infection. J Biol Chem 2012; 287: 35004-35020
40. Engel FB, Schebesta M, Duong MT, Lu G, Ren S, Madwed JB et al. p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes. Genes Dev 2005; 19: 1175-1187
41. Antrobus R, Borner GH. Improved elution conditions for native co-Immunoprecipitation. PLoS One 2011; 6: E18218
42. Saluja R, Saini R, Mitra K, Bajpai VK, Dikshit M. Ultrastructural immunogold localization of nitric oxide synthase isoforms in rat and human eosinophils. Cell Tissue Res 2010; 340: 381-388