Chronic NHE-1 blockade induces an antiapoptotic effect in the hypertrophied heart

Journal of Applied Physiology

Volumn 106, Issue 4, 2009, Pages 1325-1331

  Garciarena, Carolina D ^a   Caldiz, Claudia I ^a   Portiansky, Enrique L ^a   Chiappe De Cingolani, Gladys E ^a   Ennis, Irene L ^a,b  

^a UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

^b FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

Author keywords

Apoptosis; Cariporide; Hypertrophy; Spontaneously hypertensive rats

Indexed keywords

ANGIOTENSIN II; CARIPORIDE; CASPASE 3; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P90; SODIUM PROTON EXCHANGE PROTEIN 1; TIOPRONIN; ANTIARRHYTHMIC AGENT; GUANIDINE DERIVATIVE; SLC9A1 PROTEIN, RAT; SODIUM PROTON EXCHANGE PROTEIN; SULFONE; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; HEART VENTRICLE HYPERTROPHY; IMMUNOBLOTTING; LONG TERM CARE; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CARDIOMEGALY; CELL NUCLEUS; DRUG ANTAGONISM; DRUG EFFECT; HEART MITOCHONDRION; HEART MUSCLE; HEART MUSCLE CELL; METABOLISM; PATHOLOGY; SPONTANEOUSLY HYPERTENSIVE RAT; ULTRASTRUCTURE; WESTERN BLOTTING;

ANGIOTENSIN II; ANIMALS; ANTI-ARRHYTHMIA AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CARDIOMEGALY; CELL NUCLEUS; GUANIDINES; IN SITU NICK-END LABELING; MALE; MITOCHONDRIA, HEART; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; RATS, INBRED SHR; SODIUM-HYDROGEN ANTIPORTER; SULFONES; SUPEROXIDES;

EID: 66149129260     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.91300.2008     Document Type: Article

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