Macrocyclic biphenyl tetraoxazoles: Synthesis, evaluation as G-quadruplex stabilizers and cytotoxic activity

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 15, 2013, Pages 4511-4520

  Blankson, Gifty A ^a   Pilch, Daniel S ^b,c   Liu, Angela A ^b   Liu, Leroy F ^b,c   Rice, Joseph E ^a,c   Lavoie, Edmond J ^a,c  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

Biphenyl; Cytotoxicity; G quadruplex; G quadruplex ligand; Macrocycle; Oxazoles

Indexed keywords

DNA; GUANINE QUADRUPLEX; HEXAOXAZOLE; METV; OXAZOLE DERIVATIVE; TELOMESTATIN; UNCLASSIFIED DRUG; YAK 1161;

ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CORRELATION ANALYSIS; CYCLIZATION; DRUG CONFORMATION; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; ULTRAVIOLET SPECTROSCOPY;

EID: 84879693733     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.05.033     Document Type: Article

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