Chemoenzymatic method for producing stearidonic acid concentrates from stearidonic acid soybean oil

JAOCS, Journal of the American Oil Chemists' Society

Volumn 90, Issue 7, 2013, Pages 1011-1022

  Ifeduba, Ebenezer A ^a   Akoh, Casimir C ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

Acidolysis; Hydrolysis; Lipase; Omega 3 concentrate; Response surface methodology; Soybean oil; Stearidonic acid

Indexed keywords

ACIDOLYSIS; GRAM-SCALE SYNTHESIS; LOW-TEMPERATURE CRYSTALLIZATION; OMEGA-3; OPTIMAL CONDITIONS; REACTION CONDITIONS; RESPONSE SURFACE METHODOLOGY; STEARIDONIC ACIDS;

ENZYMATIC HYDROLYSIS; HYDROLYSIS; LIPASES; MIXTURES; OPTIMIZATION; SUBSTRATES; SURFACE PROPERTIES; SYNTHESIS (CHEMICAL);

SOYBEAN OIL;

CANDIDA RUGOSA; GLYCINE MAX; RHIZOMUCOR; RHIZOMUCOR MIEHEI;

EID: 84879686423     PISSN: 0003021X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11746-013-2251-y     Document Type: Article

References (30)

1. Lavie CJ, Milani RV, Mehra MR, Ventura HO (2009) Omega-3 polyunsaturated fatty acids and cardiovascular diseases. J Am Coll Cardiol 54:585-594
2. Makrides M, Neumann M, Simmer K, Pater J, Gibson R (1995) Are long-chain polyunsaturated fatty acids essential nutrients in infancy. Lancet 345:1463-1468
3. Farquharson J, Jamieson EC, Abbasi KA, Patrick WJ, Logan RW, Cockburn F (1995) Effect of diet on the fatty acid composition of the major phospholipids of infant cerebral cortex. Arch Disease Childhood 72:198-203
4. Harris WS (2007) Omega-3 Fatty acids and cardiovascular disease: a case for omega-3 index as a new risk factor. Pharmacol Res 55:217-223
5. Gerster H (1998) Can adults adequately convert alpha-linolenic acid(18:3n-3) to eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3)? Int J Vitam Nutr Res 68:159-173
6. Naylor RL, Goldburg RJ, Prlmavera JH, Kautsky N, Beveldge MCM, Clay J, Follae C, Lubchenco J, Mooney H, Troell M (2000) Effect of aquaculture on world fish supplies. Nature 405:1017-1024
7. Whelan J (2009) Dietary stearidonic acid is a long chain (n-3) polyunsaturated fatty acid with potential health benefits. J Nutr 139:5-10
8. Froman B, Duong C, Listello J (2011) Soybean plant corresponding to transgenic event MON87769 and methods for detection thereof. US Patent 12,865,844
9. Brenna JT (2002) Efficiency of conversion of α-linolenic acid to long chain n-3 fatty acids in man. Curr Opin Clin Nutr Metab Care 5:127-132
10. James MJ, Ursin VM, Cleland LG (2003) Metabolism of stearidonic acid in human subjects: comparison with the metabolic of other n-3 fatty acids. Am J Clin Nutr 77:1140-1145
11. Monsanto Company Omega-3 enriched soybean oil: an effective means of enriching the body with heart-healthy stearidonic acid. http://www.monsanto.com/ SiteCollectionDocuments/sda-omega3-index-study.pdf. Accessed Oct 2012
12. Nutraingredients-USA Retail omega-3 s sales to hit 34.7 billion in 2016, report predicts. http://www.nutraingredients-usa.com/Product-Categories/ Nutritional-lipids-and-oils/Retail-omega-3s-sales-to-hit-34.7-billion-in-2016- report-predicts. Accessed Oct. 2012
13. Shahidi F, Wanasundara UN (1998) Omega-3 fatty acid concentrates: nutritional aspects and production technologies. Trends Food Sci Tech 9:230-240
14. Kleiner-Shuhler L, Vazquez L, Akoh CC (2011) Purification of stearidonic acid from modified soybean oil by argentation silica chromatography. J Am Oil Chem Soc 88:1161-1171
15. Vazquez L, Akoh CC (2011) Concentration of stearidonic acid in free fatty acids and fatty acid ethyl ester forms from modified soybean oil by winterization. J Am Oil Chem Soc 88:1775-1785
16. Kleiner L, Vazquez L, Akoh CC (2012) Increasing stearidonic acid (SDA) in modified soybean oil by lipase mediated acidolysis. J Am Oil Chem Soc 89:1267-1275
17. Kleiner L, Vazquez L, Akoh CC (2012) Lipase-catalyzed concentration of stearidonic acid in modified soybean oil by partial hydrolysis. J Am Oil Chem Soc 89:1999-2010
18. Pinsirodom P, Parkin KL (2001) In lipase assays. In: Wrolstad RE, Acree TE, Decker EA, Penner MH, Reid DS, Schwartz SJ, Shoemaker CF, Smith DM, Sporns P (eds) Current protocols in food analytical chemistry. Wiley, USA, pp C3.1.1-C3.1.13
19. Official methods and recommended practices of the American Oil Chemists' Society (2009), 6th edn. AOCS, Champaign
20. Luddy FE, Bardford RA, Herb SF, Magidman P, Riemenschneider RW (1964) Pancreatic lipase hydrolysis of triacylglycerides as a semi-micro technique. J Am Oil Chem Soc 41:639-696
21. AOAC International (1998) Official methods of analysis of AOAC International, 17th edn. Method 996.01, Gaithersburg
22. Ichihara K, Fukubayashi Y (2010) Preparation of fatty acid methyl esters for gas-liquid chromatography. J Lipid Res 51:635-640
23. McNeill GP, Ackman RG, Moore SR (1996) Lipase-catalyzed enrichment of long-chain polyunsaturated fatty acids. J Am Oil Chem Soc 73:1403-1407
24. Sun T, Pigott GM, Herwig RP (2002) Lipase-assisted concentration of n-3 polyunsaturated fatty acids from viscera of farmed Atlantic salmon (Salmo salar L.). J Food Sci 67:130-136
25. Kahveci D, Xu X (2011) Repeated hydrolysis process is effective for enrichment of omega 3 polyunsaturated fatty acids in salmon oil by Candid rugosa lipase. Food Chem 129:1552-1558
26. Bottino NR, Vandenburg GA, Reiser R (1967) Resistance of certain long-chain polyunsaturated fatty acids of marine oils to pancreatic lipase hydrolysis. Lipids 2:489-493
27. Jachmanian I, Schulte E, Mukherjee KD (1996) Substrate selectivity in esterification of less common fatty acids catalyzed by lipases from different sources. Appl Micro Biotech 44:563-567
28. Lie O, Lambertsen G (1985) Digestive lipolytic enzymes in cod (Gadus morhua): fatty acid specificity. Comp Biochem Physiol 80:447-450
29. Mistry BS, Min DB (1988) Prooxidant effects of monoglycerides and diglycerides in soybean oil. J Food Sci 53:1896-1897
30. Tischer W, Wedekind F (1999) Immobilized enzymes: methods and applications. Topics Curr Chem 200:95-126