Gold-nanoparticle-based colorimetric discrimination of cancer-related point mutations with picomolar sensitivity

ACS Nano

Volumn 7, Issue 6, 2013, Pages 5530-5538

  Valentini, Paola ^a   Fiammengo, Roberto ^a   Sabella, Stefania ^a   Gariboldi, Manuela ^b,c   Maiorano, Gabriele ^a   Cingolani, Roberto ^a   Pompa, Pier Paolo ^a  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

Author keywords

biosensors; colorimetric; genotyping; gold nanoparticles; stacking interactions

Indexed keywords

COLORIMETRIC; COLORIMETRIC ASSAYS; GENOTYPING; GOLD NANOPARTICLES; NAKED-EYE DETECTION; PICOMOLAR SENSITIVITY; ROOM-TEMPERATURE CONDITIONS; STACKING INTERACTION;

BINDING ENERGY; BIOSENSORS; COLOR; COLORIMETRY; DISEASES; EYE PROTECTION; METAL NANOPARTICLES; POLYMERASE CHAIN REACTION;

GOLD;

GOLD; HELICASE; KRAS PROTEIN, HUMAN; METAL NANOPARTICLE; ONCOPROTEIN; RAS PROTEIN;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COLORIMETRY; CONFORMATION; COST BENEFIT ANALYSIS; ECONOMICS; GENETICS; HUMAN; METABOLISM; METHODOLOGY; NEOPLASM; NUCLEIC ACID HYBRIDIZATION; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; PARTICLE SIZE; POINT MUTATION; TUMOR CELL LINE;

BASE SEQUENCE; CELL LINE, TUMOR; COLORIMETRY; COST-BENEFIT ANALYSIS; DNA HELICASES; GOLD; HUMANS; METAL NANOPARTICLES; MODELS, MOLECULAR; NEOPLASMS; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE PROBES; PARTICLE SIZE; POINT MUTATION; PROTO-ONCOGENE PROTEINS; RAS PROTEINS;

EID: 84879677311     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn401757w     Document Type: Article

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