Detection of rare mutant K-ras DNA in a single-tube reaction using peptide nucleic acid as both PCR clamp and sensor probe

Nucleic Acids Research

Volumn 34, Issue 2, 2006, Pages 1-7

  Luo, Ji Dung ^a   Chan, Err Cheng ^a   Shih, Chun Liang ^a   Chen, Tai Long ^a   Liang, Ying ^b   Hwang, Tsann Long ^b   Chiou, Chiuan Chian ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; FLUORESCENT DYE; K RAS PROTEIN; MUTANT PROTEIN; PEPTIDE NUCLEIC ACID; PRIMER DNA;

ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; BLOOD SAMPLING; CANCER SCREENING; CODON; CONTROLLED STUDY; HUMAN; HUMAN CELL; ONCOGENE K RAS; PANCREAS CANCER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; SENSOR; SOMATIC MUTATION; TEMPERATURE SENSITIVITY; WILD TYPE; BLOOD; CHEMISTRY; DNA TEMPLATE; EVALUATION; GENETIC PROCEDURES; METHODOLOGY; MUTATION; NUCLEIC ACID PROBE; NUCLEOTIDE SEQUENCE; ONCOGENE RAS; PANCREAS TUMOR; TEMPERATURE;

BIOSENSING TECHNIQUES; DNA; DNA MUTATIONAL ANALYSIS; DNA PRIMERS; GENES, RAS; HUMANS; MUTATION; NUCLEIC ACID PROBES; PANCREATIC NEOPLASMS; PEPTIDE NUCLEIC ACIDS; POLYMERASE CHAIN REACTION; TEMPERATURE; TEMPLATES, GENETIC;

EID: 32644435012     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gnj008     Document Type: Article

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