Histone Acetyl Transferase 1 Is Essential for Mammalian Development, Genome Stability, and the Processing of Newly Synthesized Histones H3 and H4

PLoS Genetics

Volumn 9, Issue 6, 2013, Pages

  Nagarajan, Prabakaran ^a   Ge, Zhongqi ^a   Sirbu, Bianca ^b   Doughty, Cheryl ^c   Agudelo Garcia, Paula A ^a   Schlederer, Michaela ^d   Annunziato, Anthony T ^c   Cortez, David ^b   Kenner, Lukas ^d,e   Parthun, Mark R ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BOSTON COLLEGE   (United States)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE 1; HISTONE H3; HISTONE H4; LYSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; DEVELOPMENT; DEVELOPMENTAL DISORDER; DISEASE SEVERITY; DNA DAMAGE; EMBRYO; FEMALE; FIBROBLAST; GENE DELETION; GENE REPLICATION; GENOMIC INSTABILITY; HAT1 GENE; HISTONE ACETYLATION; HOMOZYGOTE; KNOCKOUT MOUSE; LETHALITY; LUNG; LUNG DEVELOPMENT; LUNG MALFORMATION; MAMMAL; MOUSE; NEWBORN; NONHUMAN; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; RESPIRATORY DISTRESS; SKULL MALFORMATION;

ACETYLATION; ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA REPLICATION; EMBRYONIC DEVELOPMENT; FIBROBLASTS; GENOMIC INSTABILITY; HISTONE ACETYLTRANSFERASES; HISTONES; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; MICE; MICE, KNOCKOUT;

MAMMALIA; MURINAE;

EID: 84879649988     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003518     Document Type: Article

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