-
1
-
-
0022482135
-
Normal stoichiometry of histone dimer sets is necessary for high fidelity of mitotic chromosome transmission
-
Meeks-Wagner D., Hartwell L.H. Normal stoichiometry of histone dimer sets is necessary for high fidelity of mitotic chromosome transmission. Cell 1986, 44:43-52.
-
(1986)
Cell
, vol.44
, pp. 43-52
-
-
Meeks-Wagner, D.1
Hartwell, L.H.2
-
2
-
-
0025863511
-
The regulation of histone synthesis in the cell cycle
-
Osley M.A. The regulation of histone synthesis in the cell cycle. Annu. Rev. Biochem. 1991, 60:827-861.
-
(1991)
Annu. Rev. Biochem.
, vol.60
, pp. 827-861
-
-
Osley, M.A.1
-
3
-
-
84862777348
-
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
Schwartzentruber J., et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 2012, 482:226-231.
-
(2012)
Nature
, vol.482
, pp. 226-231
-
-
Schwartzentruber, J.1
-
4
-
-
84862777410
-
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
-
Wu G., et al. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat. Genet. 2012, 44:251-253.
-
(2012)
Nat. Genet.
, vol.44
, pp. 251-253
-
-
Wu, G.1
-
5
-
-
84865863019
-
K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
-
Khuong-Quang D.A., et al. K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas. Acta Neuropathol. 2012, 124:439-447.
-
(2012)
Acta Neuropathol.
, vol.124
, pp. 439-447
-
-
Khuong-Quang, D.A.1
-
6
-
-
68249094946
-
Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysis
-
Singh R.K., et al. Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysis. Nat. Cell Biol. 2009, 11:925-933.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 925-933
-
-
Singh, R.K.1
-
7
-
-
84868246832
-
Asymmetric division of Drosophila male germline stem cell shows asymmetric histone distribution
-
Tran V., et al. Asymmetric division of Drosophila male germline stem cell shows asymmetric histone distribution. Science 2012, 338:679-682.
-
(2012)
Science
, vol.338
, pp. 679-682
-
-
Tran, V.1
-
8
-
-
84868682266
-
Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle
-
Medina R., et al. Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle. Mol. Cell. Biol. 2012, 32:3860-3871.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 3860-3871
-
-
Medina, R.1
-
9
-
-
0022531173
-
Isolation of two genes that affect mitotic chromosome transmission in S. cerevisiae
-
Meeks-Wagner D., et al. Isolation of two genes that affect mitotic chromosome transmission in S. cerevisiae. Cell 1986, 44:53-63.
-
(1986)
Cell
, vol.44
, pp. 53-63
-
-
Meeks-Wagner, D.1
-
10
-
-
77950579010
-
Hsk1- and SCF(Pof3)-dependent proteolysis of S. pombe Ams2 ensures histone homeostasis and centromere function
-
Takayama Y., et al. Hsk1- and SCF(Pof3)-dependent proteolysis of S. pombe Ams2 ensures histone homeostasis and centromere function. Dev. Cell 2010, 18:385-396.
-
(2010)
Dev. Cell
, vol.18
, pp. 385-396
-
-
Takayama, Y.1
-
11
-
-
84879602911
-
The role of dicentric chromosome formation and secondary centromere deletion in the evolution of myeloid malignancy
-
Mackinnon R.N., Campbell L.J. The role of dicentric chromosome formation and secondary centromere deletion in the evolution of myeloid malignancy. Genet. Res. Int. 2011, 2011:643628.
-
(2011)
Genet. Res. Int.
, vol.2011
, pp. 643628
-
-
Mackinnon, R.N.1
Campbell, L.J.2
-
12
-
-
33644542460
-
Mislocalization of the Drosophila centromere-specific histone CID promotes formation of functional ectopic kinetochores
-
Heun P., et al. Mislocalization of the Drosophila centromere-specific histone CID promotes formation of functional ectopic kinetochores. Dev. Cell 2006, 10:303-315.
-
(2006)
Dev. Cell
, vol.10
, pp. 303-315
-
-
Heun, P.1
-
13
-
-
84866914587
-
Cnp1 in fission yeast
-
Cnp1 in fission yeast. PLoS Genet. 2012, 8:e1002985.
-
(2012)
PLoS Genet.
, vol.8
-
-
Choi, E.S.1
-
14
-
-
0344688414
-
A Rad53 kinase-dependent surveillance mechanism that regulates histone protein levels in S. cerevisiae
-
Gunjan A., Verreault A. A Rad53 kinase-dependent surveillance mechanism that regulates histone protein levels in S. cerevisiae. Cell 2003, 115:537-549.
-
(2003)
Cell
, vol.115
, pp. 537-549
-
-
Gunjan, A.1
Verreault, A.2
-
15
-
-
0020600551
-
Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle
-
Heintz N., et al. Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Mol. Cell. Biol. 1983, 3:539-550.
-
(1983)
Mol. Cell. Biol.
, vol.3
, pp. 539-550
-
-
Heintz, N.1
-
16
-
-
0034665635
-
NPAT by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription
-
NPAT by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription. Genes Dev. 2000, 14:2298-2313.
-
(2000)
Genes Dev.
, vol.14
, pp. 2298-2313
-
-
Ma, T.1
-
17
-
-
84866112974
-
H2B Tyr37 phosphorylation suppresses expression of replication-dependent core histone genes
-
Mahajan K., et al. H2B Tyr37 phosphorylation suppresses expression of replication-dependent core histone genes. Nat. Struct. Mol. Biol. 2012, 19:930-937.
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 930-937
-
-
Mahajan, K.1
-
18
-
-
0036429193
-
The human and mouse replication-dependent histone genes
-
Marzluff W.F., et al. The human and mouse replication-dependent histone genes. Genomics 2002, 80:487-498.
-
(2002)
Genomics
, vol.80
, pp. 487-498
-
-
Marzluff, W.F.1
-
19
-
-
0019503177
-
Cell-cycle regulation of yeast histone mRNA
-
Hereford L.M., et al. Cell-cycle regulation of yeast histone mRNA. Cell 1981, 24:367-375.
-
(1981)
Cell
, vol.24
, pp. 367-375
-
-
Hereford, L.M.1
-
20
-
-
0020411152
-
Periodic transcription of yeast histone genes
-
Hereford L., et al. Periodic transcription of yeast histone genes. Cell 1982, 30:305-310.
-
(1982)
Cell
, vol.30
, pp. 305-310
-
-
Hereford, L.1
-
21
-
-
54149091257
-
Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail
-
Marzluff W.F., et al. Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail. Nat. Rev. 2008, 9:843-854.
-
(2008)
Nat. Rev.
, vol.9
, pp. 843-854
-
-
Marzluff, W.F.1
-
22
-
-
47049128024
-
Phosphorylation of threonine 61 by cyclin a/Cdk1 triggers degradation of stem-loop binding protein at the end of S phase
-
Koseoglu M.M., et al. Phosphorylation of threonine 61 by cyclin a/Cdk1 triggers degradation of stem-loop binding protein at the end of S phase. Mol. Cell. Biol. 2008, 28:4469-4479.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4469-4479
-
-
Koseoglu, M.M.1
-
23
-
-
84868686181
-
The prolyl isomerase Pin1 targets stem-loop binding protein (SLBP) to dissociate the SLBP-histone mRNA complex linking histone mRNA decay with SLBP ubiquitination
-
Krishnan N., et al. The prolyl isomerase Pin1 targets stem-loop binding protein (SLBP) to dissociate the SLBP-histone mRNA complex linking histone mRNA decay with SLBP ubiquitination. Mol. Cell. Biol. 2012, 32:4306-4322.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 4306-4322
-
-
Krishnan, N.1
-
24
-
-
0025924328
-
wee1 mitotic inhibitor is a tyrosine/serine kinase
-
wee1 mitotic inhibitor is a tyrosine/serine kinase. Nature 1991, 349:808-811.
-
(1991)
Nature
, vol.349
, pp. 808-811
-
-
Featherstone, C.1
Russell, P.2
-
25
-
-
0029000155
-
Cell cycle regulation of human WEE1
-
McGowan C.H., Russell P. Cell cycle regulation of human WEE1. EMBO J. 1995, 14:2166-2175.
-
(1995)
EMBO J.
, vol.14
, pp. 2166-2175
-
-
McGowan, C.H.1
Russell, P.2
-
26
-
-
0023662312
-
+, a gene encoding a protein kinase homolog
-
+, a gene encoding a protein kinase homolog. Cell 1987, 49:559-567.
-
(1987)
Cell
, vol.49
, pp. 559-567
-
-
Russell, P.1
Nurse, P.2
-
27
-
-
0024959919
-
+ protein kinase regulates entry into mitosis
-
+ protein kinase regulates entry into mitosis. Nature 1989, 342:39-45.
-
(1989)
Nature
, vol.342
, pp. 39-45
-
-
Gould, K.L.1
Nurse, P.2
-
28
-
-
0029048491
-
Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle
-
Watanabe N., et al. Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle. EMBO J. 1995, 14:1878-1891.
-
(1995)
EMBO J.
, vol.14
, pp. 1878-1891
-
-
Watanabe, N.1
-
29
-
-
0034665757
-
NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription
-
Zhao J., et al. NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription. Genes Dev. 2000, 14:2283-2297.
-
(2000)
Genes Dev.
, vol.14
, pp. 2283-2297
-
-
Zhao, J.1
-
30
-
-
0032520093
-
Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry
-
Zhao J., et al. Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry. Genes Dev. 1998, 12:456-461.
-
(1998)
Genes Dev.
, vol.12
, pp. 456-461
-
-
Zhao, J.1
-
31
-
-
78650754693
-
Asf1/HIRA facilitate global histone deacetylation and associate with HP1 to promote nucleosome occupancy at heterochromatic loci
-
Yamane K., et al. Asf1/HIRA facilitate global histone deacetylation and associate with HP1 to promote nucleosome occupancy at heterochromatic loci. Mol. Cell 2011, 41:56-66.
-
(2011)
Mol. Cell
, vol.41
, pp. 56-66
-
-
Yamane, K.1
-
32
-
-
0023055514
-
Identification of sequences in a yeast histone promoter involved in periodic transcription
-
Osley M.A., et al. Identification of sequences in a yeast histone promoter involved in periodic transcription. Cell 1986, 45:537-544.
-
(1986)
Cell
, vol.45
, pp. 537-544
-
-
Osley, M.A.1
-
33
-
-
0026730193
-
Identification of a new set of cell cycle-regulatory genes that regulate S-phase transcription of histone genes in Saccharomyces cerevisiae
-
Xu H., et al. Identification of a new set of cell cycle-regulatory genes that regulate S-phase transcription of histone genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 1992, 12:5249-5259.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 5249-5259
-
-
Xu, H.1
-
34
-
-
0035131425
-
HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progression
-
Hall C., et al. HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progression. Mol. Cell. Biol. 2001, 21:1854-1865.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 1854-1865
-
-
Hall, C.1
-
35
-
-
0015954720
-
Genetic control of the cell division cycle in yeast
-
Hartwell L.H., et al. Genetic control of the cell division cycle in yeast. Science 1974, 183:46-51.
-
(1974)
Science
, vol.183
, pp. 46-51
-
-
Hartwell, L.H.1
-
36
-
-
0041312681
-
The structure of the cell cycle protein Cdc14 reveals a proline-directed protein phosphatase
-
Gray C.H., et al. The structure of the cell cycle protein Cdc14 reveals a proline-directed protein phosphatase. EMBO J. 2003, 22:3524-3535.
-
(2003)
EMBO J.
, vol.22
, pp. 3524-3535
-
-
Gray, C.H.1
-
37
-
-
77953077420
-
A global protein kinase and phosphatase interaction network in yeast
-
Breitkreutz A., et al. A global protein kinase and phosphatase interaction network in yeast. Science 2010, 328:1043-1046.
-
(2010)
Science
, vol.328
, pp. 1043-1046
-
-
Breitkreutz, A.1
-
38
-
-
0032560517
-
Phosphorylation of histone H3 at serine 10 is correlated with chromosome condensation during mitosis and meiosis in Tetrahymena
-
Wei Y., et al. Phosphorylation of histone H3 at serine 10 is correlated with chromosome condensation during mitosis and meiosis in Tetrahymena. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:7480-7484.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 7480-7484
-
-
Wei, Y.1
-
39
-
-
0033520367
-
Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation
-
Goto H., et al. Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation. J. Biol. Chem. 1999, 274:25543-25549.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25543-25549
-
-
Goto, H.1
-
40
-
-
0037324194
-
Novel mitosis-specific phosphorylation of histone H3 at Thr11 mediated by Dlk/ZIP kinase
-
Preuss U., et al. Novel mitosis-specific phosphorylation of histone H3 at Thr11 mediated by Dlk/ZIP kinase. Nucleic Acids Res. 2003, 31:878-885.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 878-885
-
-
Preuss, U.1
-
41
-
-
77957814604
-
Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres
-
O'Sullivan R.J., et al. Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres. Nat. Struct. Mol. Biol. 2010, 17:1218-1225.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 1218-1225
-
-
O'Sullivan, R.J.1
-
42
-
-
0028847955
-
Conservation of deposition-related acetylation sites in newly synthesized histones H3 and H4
-
Sobel R.E., et al. Conservation of deposition-related acetylation sites in newly synthesized histones H3 and H4. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:1237-1241.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 1237-1241
-
-
Sobel, R.E.1
-
43
-
-
79959629469
-
Analysis of protein dynamics at active, stalled, and collapsed replication forks
-
Sirbu B.M., et al. Analysis of protein dynamics at active, stalled, and collapsed replication forks. Genes Dev. 2011, 25:1320-1327.
-
(2011)
Genes Dev.
, vol.25
, pp. 1320-1327
-
-
Sirbu, B.M.1
-
44
-
-
7644232055
-
WD dipeptide motifs and LXXLL motif of chicken HIRA are essential for interactions with the p48 subunit of chromatin assembly factor-1 and histone deacetylase-2 in vitro and in vivo
-
Ahmad A., et al. WD dipeptide motifs and LXXLL motif of chicken HIRA are essential for interactions with the p48 subunit of chromatin assembly factor-1 and histone deacetylase-2 in vitro and in vivo. Gene 2004, 342:125-136.
-
(2004)
Gene
, vol.342
, pp. 125-136
-
-
Ahmad, A.1
-
45
-
-
0142135133
-
Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints
-
Chow J.P., et al. Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints. J. Biol. Chem. 2003, 278:40815-40828.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 40815-40828
-
-
Chow, J.P.1
-
46
-
-
0030926775
-
Regulation of Schizosaccharomyces pombe Wee1 tyrosine kinase
-
Aligue R., et al. Regulation of Schizosaccharomyces pombe Wee1 tyrosine kinase. J. Biol. Chem. 1997, 272:13320-13325.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13320-13325
-
-
Aligue, R.1
-
47
-
-
0031034628
-
Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast
-
Rhind N., et al. Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast. Genes Dev. 1997, 11:504-511.
-
(1997)
Genes Dev.
, vol.11
, pp. 504-511
-
-
Rhind, N.1
-
48
-
-
77956517283
-
In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma
-
Mir S.E., et al. In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma. Cancer Cell 2010, 18:244-257.
-
(2010)
Cancer Cell
, vol.18
, pp. 244-257
-
-
Mir, S.E.1
-
49
-
-
33744905789
-
Murine Wee1 plays a critical role in cell cycle regulation and pre-implantation stages of embryonic development
-
Tominaga Y., et al. Murine Wee1 plays a critical role in cell cycle regulation and pre-implantation stages of embryonic development. Int. J. Biol. Sci. 2006, 2:161-170.
-
(2006)
Int. J. Biol. Sci.
, vol.2
, pp. 161-170
-
-
Tominaga, Y.1
-
50
-
-
77949410508
-
Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase
-
Beck H., et al. Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase. J. Cell Biol. 2010, 188:629-638.
-
(2010)
J. Cell Biol.
, vol.188
, pp. 629-638
-
-
Beck, H.1
-
51
-
-
84855908936
-
Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication
-
Sorensen C.S., Syljuasen R.G. Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication. Nucleic Acids Res. 2012, 40:477-486.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 477-486
-
-
Sorensen, C.S.1
Syljuasen, R.G.2
-
52
-
-
77958498222
-
The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer
-
Smith J., et al. The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer. Adv. Cancer Res. 2010, 108:73-112.
-
(2010)
Adv. Cancer Res.
, vol.108
, pp. 73-112
-
-
Smith, J.1
-
53
-
-
0012966157
-
Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A
-
Sorensen C.S., et al. Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A. Cancer Cell 2003, 3:247-258.
-
(2003)
Cancer Cell
, vol.3
, pp. 247-258
-
-
Sorensen, C.S.1
-
54
-
-
84858405757
-
Chk1 and Wee1 kinases coordinate DNA replication, chromosome condensation, and anaphase entry
-
Fasulo B., et al. Chk1 and Wee1 kinases coordinate DNA replication, chromosome condensation, and anaphase entry. Mol. Biol. Cell 2012, 23:1047-1057.
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 1047-1057
-
-
Fasulo, B.1
-
55
-
-
0031035528
-
Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation
-
O'Connell M.J., et al. Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. EMBO J. 1997, 16:545-554.
-
(1997)
EMBO J.
, vol.16
, pp. 545-554
-
-
O'Connell, M.J.1
-
56
-
-
84864557192
-
Forced mitotic entry of S-phase cells as a therapeutic strategy induced by inhibition of WEE1
-
Aarts M., et al. Forced mitotic entry of S-phase cells as a therapeutic strategy induced by inhibition of WEE1. Cancer Discov. 2012, 2:524-539.
-
(2012)
Cancer Discov.
, vol.2
, pp. 524-539
-
-
Aarts, M.1
-
57
-
-
80655141261
-
Chk1 inhibition and Wee1 inhibition combine synergistically to impede cellular proliferation
-
Davies K.D., et al. Chk1 inhibition and Wee1 inhibition combine synergistically to impede cellular proliferation. Cancer Biol. Ther. 2011, 12:788-796.
-
(2011)
Cancer Biol. Ther.
, vol.12
, pp. 788-796
-
-
Davies, K.D.1
-
58
-
-
84868689115
-
Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption
-
Beck H., et al. Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption. Mol. Cell. Biol. 2012, 32:4226-4236.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 4226-4236
-
-
Beck, H.1
-
59
-
-
80052632895
-
Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease
-
Dominguez-Kelly R., et al. Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease. J. Cell Biol. 2011, 194:567-579.
-
(2011)
J. Cell Biol.
, vol.194
, pp. 567-579
-
-
Dominguez-Kelly, R.1
-
60
-
-
62549132126
-
Cyclin A-Cdk1 regulates the origin firing program in mammalian cells
-
Katsuno Y., et al. Cyclin A-Cdk1 regulates the origin firing program in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:3184-3189.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 3184-3189
-
-
Katsuno, Y.1
-
61
-
-
0034635462
-
Interaction of Xenopus Cdc2 × cyclin A1 with the origin recognition complex
-
Romanowski P., et al. Interaction of Xenopus Cdc2 × cyclin A1 with the origin recognition complex. J. Biol. Chem. 2000, 275:4239-4243.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 4239-4243
-
-
Romanowski, P.1
-
62
-
-
0036850262
-
Stable association of mitotic cyclin B/Cdc2 to replication origins prevents endoreduplication
-
Wuarin J., et al. Stable association of mitotic cyclin B/Cdc2 to replication origins prevents endoreduplication. Cell 2002, 111:419-431.
-
(2002)
Cell
, vol.111
, pp. 419-431
-
-
Wuarin, J.1
-
63
-
-
63849151495
-
Generation and management of excess histones during the cell cycle
-
Singh R.K., et al. Generation and management of excess histones during the cell cycle. Front. Biosci. 2009, 14:3145-3158.
-
(2009)
Front. Biosci.
, vol.14
, pp. 3145-3158
-
-
Singh, R.K.1
-
64
-
-
84868089767
-
Histone dosage regulates DNA damage sensitivity in a checkpoint-independent manner by the homologous recombination pathway
-
Liang D., et al. Histone dosage regulates DNA damage sensitivity in a checkpoint-independent manner by the homologous recombination pathway. Nucleic Acids Res. 2012, 40:9604-9620.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 9604-9620
-
-
Liang, D.1
-
65
-
-
84860516339
-
Novel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae
-
Singh R.K., et al. Novel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae. PLoS ONE 2012, 7:e36295.
-
(2012)
PLoS ONE
, vol.7
-
-
Singh, R.K.1
-
66
-
-
34249025702
-
Contribution of Trf4/5 and the nuclear exosome to genome stability through regulation of histone mRNA levels in Saccharomyces cerevisiae
-
Reis C.C., Campbell J.L. Contribution of Trf4/5 and the nuclear exosome to genome stability through regulation of histone mRNA levels in Saccharomyces cerevisiae. Genetics 2007, 175:993-1010.
-
(2007)
Genetics
, vol.175
, pp. 993-1010
-
-
Reis, C.C.1
Campbell, J.L.2
-
67
-
-
79951882529
-
Prediction of associations between microRNAs and gene expression in glioma biology
-
Wuchty S., et al. Prediction of associations between microRNAs and gene expression in glioma biology. PLoS ONE 2011, 6:e14681.
-
(2011)
PLoS ONE
, vol.6
-
-
Wuchty, S.1
-
68
-
-
65249161106
-
Integrated functional, gene expression and genomic analysis for the identification of cancer targets
-
Iorns E., et al. Integrated functional, gene expression and genomic analysis for the identification of cancer targets. PLoS ONE 2009, 4:e5120.
-
(2009)
PLoS ONE
, vol.4
-
-
Iorns, E.1
-
69
-
-
77955655940
-
Identification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome
-
Murrow L.M., et al. Identification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome. Breast Cancer Res. Treat. 2010, 122:347-357.
-
(2010)
Breast Cancer Res. Treat.
, vol.122
, pp. 347-357
-
-
Murrow, L.M.1
-
70
-
-
84862185038
-
High expression of Wee1 is associated with poor disease-free survival in malignant melanoma: potential for targeted therapy
-
Magnussen G.I., et al. High expression of Wee1 is associated with poor disease-free survival in malignant melanoma: potential for targeted therapy. PLoS ONE 2012, 7:e38254.
-
(2012)
PLoS ONE
, vol.7
-
-
Magnussen, G.I.1
-
71
-
-
70949083026
-
Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents
-
Hirai H., et al. Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents. Mol. Cancer Ther. 2009, 8:2992-3000.
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 2992-3000
-
-
Hirai, H.1
-
72
-
-
83355174034
-
2 checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines
-
2 checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines. Mol. Cancer Ther. 2011, 10:2405-2414.
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 2405-2414
-
-
Sarcar, B.1
-
73
-
-
77953711939
-
MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil
-
Hirai H., et al. MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil. Cancer Biol. Ther. 2010, 9:514-522.
-
(2010)
Cancer Biol. Ther.
, vol.9
, pp. 514-522
-
-
Hirai, H.1
-
74
-
-
79952117003
-
Targeting Wee1-like protein kinase to treat cancer
-
Stathis A., Oza A. Targeting Wee1-like protein kinase to treat cancer. Drug News Perspect. 2010, 23:425-429.
-
(2010)
Drug News Perspect.
, vol.23
, pp. 425-429
-
-
Stathis, A.1
Oza, A.2
-
75
-
-
80052491760
-
MK-1775, a novel Wee1 kinase inhibitor, radiosensitizes p53-defective human tumor cells
-
Bridges K.A., et al. MK-1775, a novel Wee1 kinase inhibitor, radiosensitizes p53-defective human tumor cells. Clin. Cancer Res. 2011, 17:5638-5648.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 5638-5648
-
-
Bridges, K.A.1
-
76
-
-
79960339454
-
WEE1 kinase targeting combined with DNA-damaging cancer therapy catalyzes mitotic catastrophe
-
De Witt Hamer P.C., et al. WEE1 kinase targeting combined with DNA-damaging cancer therapy catalyzes mitotic catastrophe. Clin. Cancer Res. 2011, 17:4200-4207.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 4200-4207
-
-
De Witt Hamer, P.C.1
-
77
-
-
78650012970
-
To selectivity and beyond
-
Mack G.S. To selectivity and beyond. Nat. Biotechnol. 2010, 28:1259-1266.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 1259-1266
-
-
Mack, G.S.1
-
78
-
-
80052029516
-
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
-
Morin R.D., et al. Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma. Nature 2011, 476:298-303.
-
(2011)
Nature
, vol.476
, pp. 298-303
-
-
Morin, R.D.1
-
79
-
-
75749124332
-
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
-
Morin R.D., et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat. Genet. 2010, 42:181-185.
-
(2010)
Nat. Genet.
, vol.42
, pp. 181-185
-
-
Morin, R.D.1
-
80
-
-
84863165348
-
Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
-
McCabe M.T., et al. Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27). Proc. Natl. Acad. Sci. U.S.A. 2012, 109:2989-2994.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 2989-2994
-
-
McCabe, M.T.1
-
81
-
-
80053279825
-
The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states
-
Wigle T.J., et al. The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states. FEBS Lett. 2011, 585:3011-3014.
-
(2011)
FEBS Lett.
, vol.585
, pp. 3011-3014
-
-
Wigle, T.J.1
-
82
-
-
79952167230
-
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
-
Yap D.B., et al. Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation. Blood 2011, 117:2451-2459.
-
(2011)
Blood
, vol.117
, pp. 2451-2459
-
-
Yap, D.B.1
-
83
-
-
84867632489
-
A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells
-
Knutson S.K., et al. A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells. Nat. Chem. Biol. 2012, 8:890-896.
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 890-896
-
-
Knutson, S.K.1
-
84
-
-
84870573126
-
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
-
McCabe M.T., et al. EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations. Nature 2012, 492:108-112.
-
(2012)
Nature
, vol.492
, pp. 108-112
-
-
McCabe, M.T.1
-
85
-
-
84867606428
-
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
-
Sturm D., et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 2012, 22:425-437.
-
(2012)
Cancer Cell
, vol.22
, pp. 425-437
-
-
Sturm, D.1
-
86
-
-
84870912857
-
A role for H2B ubiquitylation in DNA replication
-
Trujillo K.M., Osley M.A. A role for H2B ubiquitylation in DNA replication. Mol. Cell 2012, 48:734-746.
-
(2012)
Mol. Cell
, vol.48
, pp. 734-746
-
-
Trujillo, K.M.1
Osley, M.A.2
-
87
-
-
84860518345
-
Codependency of H2B monoubiquitination and nucleosome reassembly on Chd1
-
Lee J.S., et al. Codependency of H2B monoubiquitination and nucleosome reassembly on Chd1. Genes Dev. 2012, 26:914-919.
-
(2012)
Genes Dev.
, vol.26
, pp. 914-919
-
-
Lee, J.S.1
-
88
-
-
79951974992
-
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks
-
Moyal L., et al. Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Mol. Cell 2011, 41:529-542.
-
(2011)
Mol. Cell
, vol.41
, pp. 529-542
-
-
Moyal, L.1
-
89
-
-
0023666061
-
Histone H2B repression causes cell-cycle-specific arrest in yeast: effects on chromosomal segregation, replication, and transcription
-
Han M., et al. Histone H2B repression causes cell-cycle-specific arrest in yeast: effects on chromosomal segregation, replication, and transcription. Cell 1987, 48:589-597.
-
(1987)
Cell
, vol.48
, pp. 589-597
-
-
Han, M.1
-
90
-
-
0023955508
-
Changes in histone gene dosage alter transcription in yeast
-
Clark-Adams C.D., et al. Changes in histone gene dosage alter transcription in yeast. Genes Dev. 1988, 2:150-159.
-
(1988)
Genes Dev.
, vol.2
, pp. 150-159
-
-
Clark-Adams, C.D.1
-
91
-
-
0029915879
-
Differential effect of H1 variant overexpression on cell cycle progression and gene expression
-
Brown D.T., et al. Differential effect of H1 variant overexpression on cell cycle progression and gene expression. Nucleic Acids Res. 1996, 24:486-493.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 486-493
-
-
Brown, D.T.1
-
92
-
-
0033621414
-
Effects of H1 histone variant overexpression on chromatin structure
-
Gunjan A., et al. Effects of H1 histone variant overexpression on chromatin structure. J. Biol. Chem. 1999, 274:37950-37956.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37950-37956
-
-
Gunjan, A.1
-
93
-
-
0035863061
-
Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression
-
Sullivan E., et al. Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression. Genes Dev. 2001, 15:173-187.
-
(2001)
Genes Dev.
, vol.15
, pp. 173-187
-
-
Sullivan, E.1
-
94
-
-
0038721220
-
H1 linker histones are essential for mouse development and affect nucleosome spacing in vivo
-
Fan Y., et al. H1 linker histones are essential for mouse development and affect nucleosome spacing in vivo. Mol. Cell. Biol. 2003, 23:4559-4572.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4559-4572
-
-
Fan, Y.1
-
95
-
-
13444270604
-
Partial depletion of histone H4 increases homologous recombination-mediated genetic instability
-
Prado F., Aguilera A. Partial depletion of histone H4 increases homologous recombination-mediated genetic instability. Mol. Cell. Biol. 2005, 25:1526-1536.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 1526-1536
-
-
Prado, F.1
Aguilera, A.2
-
96
-
-
84866948612
-
An essential role of variant histone h3.3 for ectomesenchyme potential of the cranial neural crest
-
Cox S.G., et al. An essential role of variant histone h3.3 for ectomesenchyme potential of the cranial neural crest. PLoS Genet. 2012, 8:e1002938.
-
(2012)
PLoS Genet.
, vol.8
-
-
Cox, S.G.1
-
97
-
-
58149242430
-
WSTF regulates the H2A.X. DNA damage response via a novel tyrosine kinase activity
-
Xiao A., et al. WSTF regulates the H2A.X. DNA damage response via a novel tyrosine kinase activity. Nature 2009, 457:57-62.
-
(2009)
Nature
, vol.457
, pp. 57-62
-
-
Xiao, A.1
-
98
-
-
70349975711
-
JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin
-
Dawson M.A., et al. JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin. Nature 2009, 461:819-822.
-
(2009)
Nature
, vol.461
, pp. 819-822
-
-
Dawson, M.A.1
-
99
-
-
63849187827
-
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions
-
Cook P.J., et al. Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature 2009, 458:591-596.
-
(2009)
Nature
, vol.458
, pp. 591-596
-
-
Cook, P.J.1
-
100
-
-
52449114574
-
Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer
-
Lavin M.F. Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer. Nat. Rev. Mol. Cell Biol. 2008, 9:759-769.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 759-769
-
-
Lavin, M.F.1
-
101
-
-
51649110069
-
Heterochromatin links to centromeric protection by recruiting shugoshin
-
Yamagishi Y., et al. Heterochromatin links to centromeric protection by recruiting shugoshin. Nature 2008, 455:251-255.
-
(2008)
Nature
, vol.455
, pp. 251-255
-
-
Yamagishi, Y.1
-
102
-
-
34547751335
-
HP1alpha guides neuronal fate by timing E2F-targeted genes silencing during terminal differentiation
-
Panteleeva I., et al. HP1alpha guides neuronal fate by timing E2F-targeted genes silencing during terminal differentiation. EMBO J. 2007, 26:3616-3628.
-
(2007)
EMBO J.
, vol.26
, pp. 3616-3628
-
-
Panteleeva, I.1
-
103
-
-
84866891646
-
Three distinct patterns of histone H3Y41 phosphorylation mark active genes
-
Dawson M.A., et al. Three distinct patterns of histone H3Y41 phosphorylation mark active genes. Cell Rep. 2012, 2s:470-477.
-
(2012)
Cell Rep.
, vol.2 S
, pp. 470-477
-
-
Dawson, M.A.1
-
104
-
-
78650516974
-
LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease
-
Griffiths D.S., et al. LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease. Nat. Cell Biol. 2011, 13:13-21.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 13-21
-
-
Griffiths, D.S.1
|