메뉴 건너뛰기




Volumn 288, Issue 26, 2013, Pages 18660-18671

Dynamic ubiquitination of the mitogen-activated protein kinase kinase (MAPKK) Ste7 determines mitogen-activated protein kinase (MAPK) specificity

Author keywords

[No Author keywords available]

Indexed keywords

GENE DELETION MUTANTS; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN-ACTIVATED PROTEIN KINASE KINASE; NUTRIENT DEPRIVATION; POST-TRANSLATIONAL MODIFICATIONS; PROTEASOMAL DEGRADATION; PROTEIN ACTIVITY; UBIQUITIN LIGASES;

EID: 84879593236     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.475707     Document Type: Article
Times cited : (14)

References (97)
  • 1
    • 0026696360 scopus 로고
    • Mitogen-activated protein kinases: Versatile transducers for cell signaling
    • Pelech, S. L., and Sanghera, J. S. (1992) Mitogen-activated protein kinases: versatile transducers for cell signaling. Trends Biochem. Sci. 17, 233-238
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 233-238
    • Pelech, S.L.1    Sanghera, J.S.2
  • 2
    • 0027165150 scopus 로고
    • The mitogen-activated protein kinase signal transduction pathway
    • Davis, R. J. (1993) The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 268, 14553-14556
    • (1993) J. Biol. Chem. , vol.268 , pp. 14553-14556
    • Davis, R.J.1
  • 3
    • 0027304607 scopus 로고
    • Extracellular signals and reversible protein phosphorylation: What to Mek of it all
    • DOI 10.1016/0092-8674(93)90411-I
    • Crews, C. M., and Erikson, R. L. (1993) Extracellular signals and reversible protein phosphorylation: what to Mek of it all. Cell 74, 215-217 (Pubitemid 23221696)
    • (1993) Cell , vol.74 , Issue.2 , pp. 215-217
    • Crews, C.M.1    Erikson, R.L.2
  • 4
    • 0027586171 scopus 로고
    • A conserved kinase cascade for MAP kinase activation in yeast
    • Errede, B., and Levin, D. E. (1993) A conserved kinase cascade for MAP kinase activation in yeast. Curr. Opin. Cell Biol. 5, 254-260
    • (1993) Curr. Opin. Cell Biol. , vol.5 , pp. 254-260
    • Errede, B.1    Levin, D.E.2
  • 5
    • 2942530310 scopus 로고    scopus 로고
    • ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
    • DOI 10.1128/MMBR.68.2.320-344.2004
    • Roux, P. P., and Blenis, J. (2004) ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol. Mol. Biol. Rev. 68, 320-344 (Pubitemid 38756868)
    • (2004) Microbiology and Molecular Biology Reviews , vol.68 , Issue.2 , pp. 320-344
    • Roux, P.P.1    Blenis, J.2
  • 6
    • 79952435349 scopus 로고    scopus 로고
    • Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases
    • Cargnello, M., and Roux, P. P. (2011) Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases. Microbiol. Mol. Biol. Rev. 75, 50-83
    • (2011) Microbiol. Mol. Biol. Rev. , vol.75 , pp. 50-83
    • Cargnello, M.1    Roux, P.P.2
  • 7
    • 34547216984 scopus 로고    scopus 로고
    • Function and regulation in MAPK signaling pathways: Lessons learned from the yeast Saccharomyces cerevisiae
    • DOI 10.1016/j.bbamcr.2007.05.003, PII S0167488907001218
    • Chen, R. E., and Thorner, J. (2007) Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae. Biochim. Biophys. Acta 1773, 1311-1340 (Pubitemid 47125982)
    • (2007) Biochimica et Biophysica Acta - Molecular Cell Research , vol.1773 , Issue.8 , pp. 1311-1340
    • Chen, R.E.1    Thorner, J.2
  • 8
    • 11144236161 scopus 로고    scopus 로고
    • A walk-through of the yeast mating pheromone response pathway
    • Bardwell, L. (2005) A walk-through of the yeast mating pheromone response pathway. Peptides 26, 339-350
    • (2005) Peptides , vol.26 , pp. 339-350
    • Bardwell, L.1
  • 9
    • 0028556727 scopus 로고
    • Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae
    • Bardwell, L., Cook, J. G., Inouye, C. J., and Thorner, J. (1994) Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae. Dev. Biol. 166, 363-379
    • (1994) Dev. Biol. , vol.166 , pp. 363-379
    • Bardwell, L.1    Cook, J.G.2    Inouye, C.J.3    Thorner, J.4
  • 10
    • 0025885772 scopus 로고
    • Signal transduction during pheromone response in yeast
    • Marsh, L., Neiman, A. M., and Herskowitz, I. (1991) Signal transduction during pheromone response in yeast. Annu. Rev. Cell Biol. 7, 699-728
    • (1991) Annu. Rev. Cell Biol. , vol.7 , pp. 699-728
    • Marsh, L.1    Neiman, A.M.2    Herskowitz, I.3
  • 11
    • 0027253814 scopus 로고
    • FUS3 phosphorylates multiple components of the mating signal transduction cascade: Evidence for STE12 and FAR1
    • Elion, E. A., Satterberg, B., and Kranz, J. E. (1993) FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1. Mol. Biol. Cell 4, 495-510 (Pubitemid 23150914)
    • (1993) Molecular Biology of the Cell , vol.4 , Issue.5 , pp. 495-510
    • Elion, E.A.1    Satterberg, B.2    Kranz, J.E.3
  • 12
    • 0032035043 scopus 로고    scopus 로고
    • Signal transduction by MAP kinase cascades in budding yeast
    • Posas, F., Takekawa, M., and Saito, H. (1998) Signal transduction by MAP kinase cascades in budding yeast. Curr. Opin. Microbiol. 1, 175-182 (Pubitemid 128428057)
    • (1998) Current Opinion in Microbiology , vol.1 , Issue.2 , pp. 175-182
    • Posas, F.1    Takekawa, M.2    Saito, H.3
  • 13
    • 0028920365 scopus 로고
    • The proliferation of MAP kinase signaling pathways in yeast
    • Levin, D. E., and Errede, B. (1995) The proliferation of MAP kinase signaling pathways in yeast. Curr. Opin. Cell Biol. 7, 197-202
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 197-202
    • Levin, D.E.1    Errede, B.2
  • 14
    • 0036891750 scopus 로고    scopus 로고
    • The sensing of nutritional status and the relationship to filamentous growth in Saccharomyces cerevisiae
    • DOI 10.1016/S1567-1356(02)00133-2, PII S1567135602001332
    • Gagiano, M., Bauer, F. F., and Pretorius, I. S. (2002) The sensing of nutritional status and the relationship to filamentous growth in Saccharomyces cerevisiae. FEMS Yeast Res. 2, 433-470 (Pubitemid 35373953)
    • (2002) FEMS Yeast Research , vol.2 , Issue.4 , pp. 433-470
    • Gagiano, M.1    Bauer, F.F.2    Pretorius, I.S.3
  • 15
    • 0036224499 scopus 로고    scopus 로고
    • Sensing, signalling and integrating physical processes during Saccharomyces cerevisiae invasive and filamentous growth
    • Palecek, S. P., Parikh, A. S., and Kron, S. J. (2002) Sensing, signalling, and integrating physical processes during Saccharomyces cerevisiae invasive and filamentous growth. Microbiology 148, 893-907 (Pubitemid 34436768)
    • (2002) Microbiology , vol.148 , Issue.4 , pp. 893-907
    • Palecek, S.P.1    Parikh, A.S.2    Kron, S.J.3
  • 16
    • 77956834099 scopus 로고    scopus 로고
    • Fine regulation of Saccharomyces cerevisiae MAPK pathways by post-translational modifications
    • Molina, M., Cid, V. J., and Martín, H. (2010) Fine regulation of Saccharomyces cerevisiae MAPK pathways by post-translational modifications. Yeast 27, 503-511
    • (2010) Yeast , vol.27 , pp. 503-511
    • Molina, M.1    Cid, V.J.2    Martín, H.3
  • 17
    • 84155192294 scopus 로고    scopus 로고
    • Post-transcriptional regulation of the Ras-ERK/MAPK signaling pathway
    • Whelan, J. T., Hollis, S. E., Cha, D. S., Asch, A. S., and Lee, M. H. (2012) Post-transcriptional regulation of the Ras-ERK/MAPK signaling pathway. J. Cell. Physiol. 227, 1235-1241
    • (2012) J. Cell. Physiol. , vol.227 , pp. 1235-1241
    • Whelan, J.T.1    Hollis, S.E.2    Cha, D.S.3    Asch, A.S.4    Lee, M.H.5
  • 19
    • 4444318673 scopus 로고    scopus 로고
    • The SCF ubiquitin ligase: Insights into a molecular machine
    • DOI 10.1038/nrm1471
    • Cardozo, T., and Pagano, M. (2004) The SCF ubiquitin ligase: insights into a molecular machine. Nat. Rev. Mol. Cell Biol. 5, 739-751 (Pubitemid 39208183)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.9 , pp. 739-751
    • Cardozo, T.1    Pagano, M.2
  • 20
    • 0030693702 scopus 로고    scopus 로고
    • Phosphorylation- and ubiquitin-dependent degradation of the cyclin- dependent kinase inhibitor Far1p in budding yeast
    • Henchoz, S., Chi, Y., Catarin, B., Herskowitz, I., Deshaies, R. J., and Peter, M. (1997) Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast. Genes Dev. 11, 3046-3060 (Pubitemid 27508514)
    • (1997) Genes and Development , vol.11 , Issue.22 , pp. 3046-3060
    • Henchoz, S.1    Chi, Y.2    Catarin, B.3    Herskowitz, I.4    Deshaies, R.J.5    Peter, M.6
  • 21
    • 0030662523 scopus 로고    scopus 로고
    • F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
    • DOI 10.1016/S0092-8674(00)80403-1
    • Skowyra, D., Craig, K. L., Tyers, M., Elledge, S. J., and Harper, J. W. (1997) F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91, 209-219 (Pubitemid 27456388)
    • (1997) Cell , vol.91 , Issue.2 , pp. 209-219
    • Skowyra, D.1    Craig, K.L.2    Tyers, M.3    Elledge, S.J.4    Harper, J.W.5
  • 22
    • 0030695025 scopus 로고    scopus 로고
    • A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
    • DOI 10.1016/S0092-8674(00)80404-3
    • Feldman, R. M., Correll, C. C., Kaplan, K. B., and Deshaies, R. J. (1997) A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell 91, 221-230 (Pubitemid 27456389)
    • (1997) Cell , vol.91 , Issue.2 , pp. 221-230
    • Feldman, R.M.R.1    Correll, C.C.2    Kaplan, K.B.3    Deshaies, R.J.4
  • 23
    • 77953108709 scopus 로고    scopus 로고
    • Systematic analysis of essential genes reveals important regulators of G protein signaling
    • Cappell, S. D., Baker, R., Skowyra, D., and Dohlman, H. G. (2010) Systematic analysis of essential genes reveals important regulators of G protein signaling. Mol. Cell 38, 746-757
    • (2010) Mol. Cell , vol.38 , pp. 746-757
    • Cappell, S.D.1    Baker, R.2    Skowyra, D.3    Dohlman, H.G.4
  • 24
    • 58249105893 scopus 로고    scopus 로고
    • Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence
    • Garrenton, L. S., Braunwarth, A., Irniger, S., Hurt, E., Künzler, M., and Thorner, J. (2009) Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence. Mol. Cell. Biol. 29, 582-601
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 582-601
    • Garrenton, L.S.1    Braunwarth, A.2    Irniger, S.3    Hurt, E.4    Künzler, M.5    Thorner, J.6
  • 25
    • 67650620318 scopus 로고    scopus 로고
    • Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes
    • Reyes-Turcu, F. E., Ventii, K. H., and Wilkinson, K. D. (2009) Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annu. Rev. Biochem. 78, 363-397
    • (2009) Annu. Rev. Biochem. , vol.78 , pp. 363-397
    • Reyes-Turcu, F.E.1    Ventii, K.H.2    Wilkinson, K.D.3
  • 26
    • 84867174770 scopus 로고    scopus 로고
    • Combined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificity
    • Hao, N., Yildirim, N., Nagiec, M. J., Parnell, S. C., Errede, B., Dohlman, H. G., and Elston, T. C. (2012) Combined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificity. Mol. Biol. Cell 23, 3899-3910
    • (2012) Mol. Biol. Cell , vol.23 , pp. 3899-3910
    • Hao, N.1    Yildirim, N.2    Nagiec, M.J.3    Parnell, S.C.4    Errede, B.5    Dohlman, H.G.6    Elston, T.C.7
  • 27
    • 34248575122 scopus 로고    scopus 로고
    • Systems biology analysis of G protein and MAP kinase signaling in yeast
    • DOI 10.1038/sj.onc.1210416, PII 1210416
    • Hao, N., Behar, M., Elston, T. C., and Dohlman, H. G. (2007) Systems biology analysis of G protein and MAP kinase signaling in yeast. Oncogene 26, 3254-3266 (Pubitemid 46763019)
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3254-3266
    • Hao, N.1    Behar, M.2    Elston, T.C.3    Dohlman, H.G.4
  • 28
    • 0035928744 scopus 로고    scopus 로고
    • MAPK specificity in the yeast pheromone response independent of transcriptional activation
    • DOI 10.1016/S0960-9822(01)00370-0
    • Breitkreutz, A., Boucher, L., and Tyers, M. (2001) MAPK specificity in the yeast pheromone response independent of transcriptional activation. Curr. Biol. 11, 1266-1271 (Pubitemid 32774083)
    • (2001) Current Biology , vol.11 , Issue.16 , pp. 1266-1271
    • Breitkreutz, A.1    Boucher, L.2    Tyers, M.3
  • 29
    • 0032920977 scopus 로고    scopus 로고
    • Relative dependence of different outputs of the Saccharomyces cerevisiae pheromone response pathway on the MAP kinase Fus3p
    • Farley, F. W., Satterberg, B., Goldsmith, E. J., and Elion, E. A. (1999) Relative dependence of different outputs of the Saccharomyces cerevisiae pheromone response pathway on the MAP kinase Fus3p. Genetics 151, 1425-1444 (Pubitemid 29177553)
    • (1999) Genetics , vol.151 , Issue.4 , pp. 1425-1444
    • Farley, F.W.1    Satterberg, B.2    Goldsmith, E.J.3    Elion, E.A.4
  • 30
    • 0034796049 scopus 로고    scopus 로고
    • Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation
    • DOI 10.1016/S1097-2765(01)00322-7
    • Sabbagh, W., Jr., Flatauer, L. J., Bardwell, A. J., and Bardwell, L. (2001) Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation. Mol. Cell 8, 683-691 (Pubitemid 32946944)
    • (2001) Molecular Cell , vol.8 , Issue.3 , pp. 683-691
    • Sabbagh Jr., W.1    Flatauer, L.J.2    Bardwell A.Jane3    Bardwell, L.4
  • 31
    • 0031128205 scopus 로고    scopus 로고
    • Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates
    • Tedford, K., Kim, S., Sa, D., Stevens, K., and Tyers, M. (1997) Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates. Curr. Biol. 7, 228-238 (Pubitemid 27176848)
    • (1997) Current Biology , vol.7 , Issue.4 , pp. 228-238
    • Tedford, K.1    Kim, S.2    Sa, D.3    Stevens, K.4    Tyers, M.5
  • 32
    • 0037013202 scopus 로고    scopus 로고
    • Pheromone-dependent ubiquitination of the mitogen-activated protein kinase kinase Ste7
    • DOI 10.1074/jbc.M111733200
    • Wang, Y., and Dohlman, H. G. (2002) Pheromone-dependent ubiquitination of the mitogen-activated protein kinase kinase Ste7. J. Biol. Chem. 277, 15766-15772 (Pubitemid 34967852)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.18 , pp. 15766-15772
    • Wang, Y.1    Dohlman, H.G.2
  • 33
    • 0037591222 scopus 로고    scopus 로고
    • Regulation of Ste7 ubiquitination by Ste11 phosphorylation and the Skp1-Cullin-F-box complex
    • DOI 10.1074/jbc.M301272200
    • Wang, Y., Ge, Q., Houston, D., Thorner, J., Errede, B., and Dohlman, H. G. (2003) Regulation of Ste7 ubiquitination by Ste11 phosphorylation and the Skp1-Cullin-F-box complex. J. Biol. Chem. 278, 22284-22289 (Pubitemid 36830277)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.25 , pp. 22284-22289
    • Wang, Y.1    Ge, Q.2    Houston, D.3    Thorner, J.4    Errede, B.5    Dohlman, H.G.6
  • 34
    • 0035720749 scopus 로고    scopus 로고
    • Analysis of RGS proteins in Saccharomyces cerevisiae
    • Hoffman, G. A., Garrison, T. R., and Dohlman, H. G. (2002) Analysis of RGS proteins in Saccharomyces cerevisiae. Methods Enzymol. 344, 617-631
    • (2002) Methods Enzymol. , vol.344 , pp. 617-631
    • Hoffman, G.A.1    Garrison, T.R.2    Dohlman, H.G.3
  • 35
    • 4744346430 scopus 로고    scopus 로고
    • Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support fus3-dependent mating in yeast
    • DOI 10.1128/MCB.24.20.9221-9238.2004
    • Maleri, S., Ge, Q., Hackett, E. A., Wang, Y., Dohlman, H. G., and Errede, B. (2004) Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast. Mol. Cell. Biol. 24, 9221-9238 (Pubitemid 39313923)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.20 , pp. 9221-9238
    • Maleri, S.1    Ge, Q.2    Hackett, E.A.3    Wang, Y.4    Dohlman, H.G.5    Errede, B.6
  • 36
    • 34548324648 scopus 로고    scopus 로고
    • The RACK1 ortholog Asc1 functions as a G-protein β subunit coupled to glucose responsiveness in yeast
    • DOI 10.1074/jbc.M702569200
    • Zeller, C. E., Parnell, S. C., and Dohlman, H. G. (2007) The RACK1 ortholog Asc1 functions as a G-protein β subunit coupled to glucose responsiveness in yeast. J. Biol. Chem. 282, 25168-25176 (Pubitemid 47347565)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.34 , pp. 25168-25176
    • Zeller, C.E.1    Parnell, S.C.2    Dohlman, H.G.3
  • 37
    • 80155192462 scopus 로고    scopus 로고
    • Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress
    • Solé, C., Nadal-Ribelles, M., Kraft, C., Peter, M., Posas, F., and de Nadal, E. (2011) Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress. EMBO J. 30, 3274-3284
    • (2011) EMBO J. , vol.30 , pp. 3274-3284
    • Solé, C.1    Nadal-Ribelles, M.2    Kraft, C.3    Peter, M.4    Posas, F.5    De Nadal, E.6
  • 38
    • 34047259513 scopus 로고    scopus 로고
    • A Systems-Biology Analysis of Feedback Inhibition in the Sho1 Osmotic-Stress-Response Pathway
    • DOI 10.1016/j.cub.2007.02.044, PII S0960982207010214
    • Hao, N., Behar, M., Parnell, S. C., Torres, M. P., Borchers, C. H., Elston, T. C., and Dohlman, H. G. (2007) A systems-biology analysis of feedback inhibition in the Sho1 osmotic-stress-response pathway. Curr. Biol. 17, 659-667 (Pubitemid 46552242)
    • (2007) Current Biology , vol.17 , Issue.8 , pp. 659-667
    • Hao, N.1    Behar, M.2    Parnell, S.C.3    Torres, M.P.4    Borchers, C.H.5    Elston, T.C.6    Dohlman, H.G.7
  • 40
    • 4344672574 scopus 로고    scopus 로고
    • Identification of yeast pheromone pathway modulators by high-throughput agonist response profiling of a yeast gene knockout strain collection
    • DOI 10.1016/S0076-6879(04)89024-4, PII S0076687904890244
    • Chasse, S. A., and Dohlman, H. G. (2004) Identification of yeast pheromone pathway modulators by high-throughput agonist response profiling of a yeast gene knockout strain collection. Methods Enzymol. 389, 399-409 (Pubitemid 39119081)
    • (2004) Methods in Enzymology , vol.389 , pp. 399-409
    • Chasse, S.A.1    Dohlman, H.G.2
  • 41
    • 20144383113 scopus 로고    scopus 로고
    • Phosphorylation of the RGS protein Sst2 by the MAP kinase Fus3 and use of Sst2 as a model to analyze determinants of substrate sequence specificity
    • DOI 10.1021/bi0503091
    • Parnell, S. C., Marotti, L. A., Jr., Kiang, L., Torres, M. P., Borchers, C. H., and Dohlman, H. G. (2005) Phosphorylation of the RGS protein Sst2 by theMAPkinase Fus3 and use of Sst2 as a model to analyze determinants of substrate sequence specificity. Biochemistry 44, 8159-8166 (Pubitemid 40776677)
    • (2005) Biochemistry , vol.44 , Issue.22 , pp. 8159-8166
    • Parnell, S.C.1    Marotti Jr., L.A.2    Kiang, L.3    Torres, M.P.4    Borchers, C.H.5    Dohlman, H.G.6
  • 42
    • 0026725796 scopus 로고
    • Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1
    • Gartner, A., Nasmyth, K., and Ammerer, G. (1992) Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1. Genes Dev. 6, 1280-1292
    • (1992) Genes Dev. , vol.6 , pp. 1280-1292
    • Gartner, A.1    Nasmyth, K.2    Ammerer, G.3
  • 43
    • 33745432883 scopus 로고    scopus 로고
    • Regulation of mating and filamentation genes by two distinct Ste12 complexes in Saccharomyces cerevisiae
    • DOI 10.1128/MCB.02053-05
    • Chou, S., Lane, S., and Liu, H. (2006) Regulation of mating and filamentation genes by two distinct Ste12 complexes in Saccharomyces cerevisiae. Mol. Cell. Biol. 26, 4794-4805 (Pubitemid 43955798)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.13 , pp. 4794-4805
    • Chou, S.1    Lane, S.2    Liu, H.3
  • 44
    • 0030688862 scopus 로고    scopus 로고
    • Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway
    • DOI 10.1038/36355
    • Cook, J. G., Bardwell, L., and Thorner, J. (1997) Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway. Nature 390, 85-88 (Pubitemid 27494761)
    • (1997) Nature , vol.390 , Issue.6655 , pp. 85-88
    • Cook, J.G.1    Bardwell, L.2    Thorner, J.3
  • 46
    • 79955941973 scopus 로고    scopus 로고
    • PTMs in conversation: Activity and function of deubiquitinating enzymes regulated via post-translational modifications
    • Kessler, B. M., and Edelmann, M. J. (2011) PTMs in conversation: activity and function of deubiquitinating enzymes regulated via post-translational modifications. Cell Biochem. Biophys. 60, 21-38
    • (2011) Cell Biochem. Biophys. , vol.60 , pp. 21-38
    • Kessler, B.M.1    Edelmann, M.J.2
  • 48
    • 32444442870 scopus 로고    scopus 로고
    • The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway
    • Bhattacharyya, R. P., Reményi, A., Good, M. C., Bashor, C. J., Falick, A. M., and Lim, W. A. (2006) The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway. Science 311, 822-826
    • (2006) Science , vol.311 , pp. 822-826
    • Bhattacharyya, R.P.1    Reményi, A.2    Good, M.C.3    Bashor, C.J.4    Falick, A.M.5    Lim, W.A.6
  • 49
    • 0344012556 scopus 로고    scopus 로고
    • Regulators of G protein signaling and transient activation of signaling: Experimental and computational analysis reveals negative and positive feedback controls on G protein activity
    • DOI 10.1074/jbc.M308432200
    • Hao, N., Yildirim, N., Wang, Y., Elston, T. C., and Dohlman, H. G. (2003) Regulators of G protein signaling and transient activation of signaling: experimental and computational analysis reveals negative and positive feedback controls on G protein activity. J. Biol. Chem. 278, 46506-46515 (Pubitemid 37452223)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.47 , pp. 46506-46515
    • Hao, N.1    Yildirim, N.2    Wang, Y.3    Elston, T.C.4    Dohlman, H.G.5
  • 50
    • 84866006042 scopus 로고    scopus 로고
    • Governance of endocytic trafficking and signaling by reversible ubiquitylation
    • Clague, M. J., Liu, H., and Urbé, S. (2012) Governance of endocytic trafficking and signaling by reversible ubiquitylation. Dev. Cell 23, 457-467
    • (2012) Dev. Cell , vol.23 , pp. 457-467
    • Clague, M.J.1    Liu, H.2    Urbé, S.3
  • 51
    • 84866855674 scopus 로고    scopus 로고
    • Ubiquitination of G protein-coupled receptors: Functional implications and drug discovery
    • Dores, M. R., and Trejo, J. (2012) Ubiquitination of G protein-coupled receptors: functional implications and drug discovery. Mol. Pharmacol. 82, 563-570
    • (2012) Mol. Pharmacol. , vol.82 , pp. 563-570
    • Dores, M.R.1    Trejo, J.2
  • 52
    • 84861783400 scopus 로고    scopus 로고
    • Ubiquitin-binding proteins: Decoders of ubiquitin-mediated cellular functions
    • Husnjak, K., and Dikic, I. (2012) Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions. Annu. Rev. Biochem. 81, 291-322
    • (2012) Annu. Rev. Biochem. , vol.81 , pp. 291-322
    • Husnjak, K.1    Dikic, I.2
  • 53
    • 0032533588 scopus 로고    scopus 로고
    • A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin-mediated protein degradation
    • Chung, C. Y., Reddy, T. B., Zhou, K., and Firtel, R. A. (1998) A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin-mediated protein degradation. Genes Dev. 12, 3564-3578 (Pubitemid 28553247)
    • (1998) Genes and Development , vol.12 , Issue.22 , pp. 3564-3578
    • Chung, C.Y.1    Reddy, T.B.K.2    Zhou, K.3    Firtel, R.A.4
  • 54
    • 77957728785 scopus 로고    scopus 로고
    • Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury
    • Xiong, X., Wang, X., Ewanek, R., Bhat, P., Diantonio, A., and Collins, C. A. (2010) Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury. J. Cell Biol. 191, 211-223
    • (2010) J. Cell Biol. , vol.191 , pp. 211-223
    • Xiong, X.1    Wang, X.2    Ewanek, R.3    Bhat, P.4    Diantonio, A.5    Collins, C.A.6
  • 55
    • 0036007417 scopus 로고    scopus 로고
    • Fat facets does a Highwire act at the synapse
    • DOI 10.1002/bies.10030
    • Fischer, J. A., and Overstreet, E. (2002) Fat facets does a Highwire act at the synapse. BioEssays 24, 13-16 (Pubitemid 34108415)
    • (2002) BioEssays , vol.24 , Issue.1 , pp. 13-16
    • Fischer, J.A.1    Overstreet, E.2
  • 56
    • 0035954743 scopus 로고    scopus 로고
    • Ubiquitination-dependent mechanisms regulate synaptic growth and function
    • DOI 10.1038/35086595
    • DiAntonio, A., Haghighi, A. P., Portman, S. L., Lee, J. D., Amaranto, A. M., and Goodman, C. S. (2001) Ubiquitination-dependent mechanisms regulate synaptic growth and function. Nature 412, 449-452 (Pubitemid 32702710)
    • (2001) Nature , vol.412 , Issue.6845 , pp. 449-452
    • DiAntonio, A.1    Haghighi, A.P.2    Portman, S.L.3    Lee, J.D.4    Amaranto, A.M.5    Goodman, C.S.6
  • 57
    • 0037462764 scopus 로고    scopus 로고
    • Yersinia effector YopJ inhibits yeast MAPK signaling pathways by an evolutionarily conserved mechanism
    • DOI 10.1074/jbc.M209905200
    • Yoon, S., Liu, Z., Eyobo, Y., and Orth, K. (2003) Yersinia effector YopJ inhibits yeast MAPK signaling pathways by an evolutionarily conserved mechanism. J. Biol. Chem. 278, 2131-2135 (Pubitemid 36801277)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.4 , pp. 2131-2135
    • Yoon, S.1    Liu, Z.2    Eyobo, Y.3    Orth, K.4
  • 59
    • 78650915537 scopus 로고    scopus 로고
    • Deubiquitinases in the regulation of NF-κB signaling
    • Harhaj, E. W., and Dixit, V. M. (2011) Deubiquitinases in the regulation of NF-κB signaling. Cell Res. 21, 22-39
    • (2011) Cell Res. , vol.21 , pp. 22-39
    • Harhaj, E.W.1    Dixit, V.M.2
  • 60
    • 77449150629 scopus 로고    scopus 로고
    • CYLD: A tumor suppressor deubiquitinase regulating NF-κB activation and diverse biological processes
    • Sun, S. C. (2010) CYLD: a tumor suppressor deubiquitinase regulating NF-κB activation and diverse biological processes. Cell Death Differ. 17, 25-34
    • (2010) Cell Death Differ. , vol.17 , pp. 25-34
    • Sun, S.C.1
  • 61
    • 77954310807 scopus 로고    scopus 로고
    • Ubiquitin chain cleavage: CYLD at work
    • Massoumi, R. (2010) Ubiquitin chain cleavage: CYLD at work. Trends Biochem. Sci. 35, 392-399
    • (2010) Trends Biochem. Sci. , vol.35 , pp. 392-399
    • Massoumi, R.1
  • 62
    • 84873553697 scopus 로고    scopus 로고
    • CYLD regulates RhoA activity by modulating LARG ubiquitination
    • Yang, Y., Sun, L., Tala, Gao, J., Li, D., Zhou, J., and Liu, M. (2013) CYLD regulates RhoA activity by modulating LARG ubiquitination. PLoS One 8, e55833
    • (2013) PLoS One , vol.8
    • Yang, Y.1    Sun, L.2    Tala3    Gao, J.4    Li, D.5    Zhou, J.6    Liu, M.7
  • 63
    • 11244341060 scopus 로고    scopus 로고
    • Negative regulation of JNK signaling by the tumor suppressor CYLD
    • DOI 10.1074/jbc.M411049200
    • Reiley, W., Zhang, M., and Sun, S. C. (2004) Negative regulation of JNK signaling by the tumor suppressor CYLD. J. Biol. Chem. 279, 55161-55167 (Pubitemid 40066510)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.53 , pp. 55161-55167
    • Reiley, W.1    Zhang, M.2    Sun, S.-C.3
  • 64
    • 84885642498 scopus 로고    scopus 로고
    • A portrayal of E3 ubiquitin ligases and deubiquitylases in cancer
    • in press
    • Satija, Y. K., Bhardwaj, A., and Das, S. (2013) A portrayal of E3 ubiquitin ligases and deubiquitylases in cancer. Int. J. Cancer, in press
    • (2013) Int. J. Cancer
    • Satija, Y.K.1    Bhardwaj, A.2    Das, S.3
  • 65
    • 84862664368 scopus 로고    scopus 로고
    • Targeting the ubiquitin+ proteasome system in solid tumors
    • Driscoll, J. J., and Woodle, E. S. (2012) Targeting the ubiquitin+ proteasome system in solid tumors. Semin. Hematol. 49, 277-283
    • (2012) Semin. Hematol. , vol.49 , pp. 277-283
    • Driscoll, J.J.1    Woodle, E.S.2
  • 66
    • 84861194412 scopus 로고    scopus 로고
    • Pirh2 RING-finger E3 ubiquitin ligase: Its role in tumorigenesis and cancer therapy
    • Jung, Y. S., Qian, Y., and Chen, X. (2012) Pirh2 RING-finger E3 ubiquitin ligase: its role in tumorigenesis and cancer therapy. FEBS Lett. 586, 1397-1402
    • (2012) FEBS Lett. , vol.586 , pp. 1397-1402
    • Jung, Y.S.1    Qian, Y.2    Chen, X.3
  • 67
    • 84858127817 scopus 로고    scopus 로고
    • Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control
    • Mocciaro, A., and Rape, M. (2012) Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control. J. Cell Sci. 125, 255-263
    • (2012) J. Cell Sci. , vol.125 , pp. 255-263
    • Mocciaro, A.1    Rape, M.2
  • 68
    • 84860208090 scopus 로고    scopus 로고
    • Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis
    • Wang, G., Chan, C. H., Gao, Y., and Lin, H. K. (2012) Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis. Chin. J. Cancer 31, 169-177
    • (2012) Chin. J. Cancer , vol.31 , pp. 169-177
    • Wang, G.1    Chan, C.H.2    Gao, Y.3    Lin, H.K.4
  • 69
    • 84856709112 scopus 로고    scopus 로고
    • SCF ubiquitin ligases in the maintenance of genome stability
    • Silverman, J. S., Skaar, J. R., and Pagano, M. (2012) SCF ubiquitin ligases in the maintenance of genome stability. Trends Biochem. Sci. 37, 66-73
    • (2012) Trends Biochem. Sci. , vol.37 , pp. 66-73
    • Silverman, J.S.1    Skaar, J.R.2    Pagano, M.3
  • 70
    • 79958010386 scopus 로고    scopus 로고
    • Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction
    • Inuzuka, H., Fukushima, H., Shaik, S., and Wei, W. (2010) Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction. Oncotarget 1, 685-690
    • (2010) Oncotarget , vol.1 , pp. 685-690
    • Inuzuka, H.1    Fukushima, H.2    Shaik, S.3    Wei, W.4
  • 71
    • 0030659821 scopus 로고    scopus 로고
    • sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins
    • Hubbard, E. J., Wu, G., Kitajewski, J., and Greenwald, I. (1997) sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins. Genes Dev. 11, 3182-3193 (Pubitemid 27528058)
    • (1997) Genes and Development , vol.11 , Issue.23 , pp. 3182-3193
    • Hubbard, E.J.A.1    Wu, G.2    Kitajewski, J.3    Greenwald, I.4
  • 72
    • 0035921928 scopus 로고    scopus 로고
    • Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines
    • DOI 10.1038/35095068
    • Moberg, K. H., Bell, D. W., Wahrer, D. C., Haber, D. A., and Hariharan, I. K. (2001) Archipelago regulates cyclin E levels in Drosophila and is mutated in human cancer cell lines. Nature 413, 311-316 (Pubitemid 32905852)
    • (2001) Nature , vol.413 , Issue.6853 , pp. 311-316
    • Moberg, K.H.1    Bell, D.W.2    Wahrer, D.C.R.3    Haber, D.A.4    Hariharan, I.K.5
  • 73
    • 0035885864 scopus 로고    scopus 로고
    • Characterization of a mouse gene (Fbxw6) that encodes a homologue of Caenorhabditis elegans SEL-10
    • DOI 10.1006/geno.2001.6658
    • Maruyama, S., Hatakeyama, S., Nakayama, K., Ishida, N., and Kawakami, K. (2001) Characterization of a mouse gene (Fbxw6) that encodes a homologue of Caenorhabditis elegans SEL-10. Genomics 78, 214-222 (Pubitemid 34001425)
    • (2001) Genomics , vol.78 , Issue.3 , pp. 214-222
    • Maruyama, S.-I.1    Hatakeyama, S.2    Nakayama, K.3    Ishida, N.4    Kawakami, K.5    Nakayama, K.-I.6
  • 74
    • 0035812709 scopus 로고    scopus 로고
    • Fbw7 ubiquitin ligase
    • DOI 10.1126/science.1065203
    • Koepp, D. M., Schaefer, L. K., Ye, X., Keyomarsi, K., Chu, C., Harper, J. W., and Elledge, S. J. (2001) Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase. Science 294, 173-177 (Pubitemid 32952972)
    • (2001) Science , vol.294 , Issue.5540 , pp. 173-177
    • Koepp, D.M.1    Schaefer, L.K.2    Ye, X.3    Keyomarsi, K.4    Chu, C.5    Harper, J.W.6    Elledge, S.J.7
  • 75
    • 38549086019 scopus 로고    scopus 로고
    • FBW7 ubiquitin ligase: A tumour suppressor at the crossroads of cell division, growth and differentiation
    • DOI 10.1038/nrc2290, PII NRC2290
    • Welcker, M., and Clurman, B. E. (2008) FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat. Rev. Cancer 8, 83-93 (Pubitemid 351161321)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.2 , pp. 83-93
    • Welcker, M.1    Clurman, B.E.2
  • 76
    • 33644856538 scopus 로고    scopus 로고
    • Pheromone-regulated sumoylation of transcription factors that mediate the invasive to mating developmental switch in yeast
    • DOI 10.1074/jbc.M508985200
    • Wang, Y., and Dohlman, H. G. (2006) Pheromone-regulated sumoylation of transcription factors that mediate the invasive to mating developmental switch in yeast. J. Biol. Chem. 281, 1964-1969 (Pubitemid 43845782)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.4 , pp. 1964-1969
    • Wang, Y.1    Dohlman, H.G.2
  • 77
    • 11144352246 scopus 로고    scopus 로고
    • Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast
    • DOI 10.1016/j.cell.2004.11.052, PII S0092867404011651
    • Bao, M. Z., Schwartz, M. A., Cantin, G. T., Yates, J. R., 3rd, and Madhani, H. D. (2004) Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast. Cell 119, 991-1000 (Pubitemid 40037612)
    • (2004) Cell , vol.119 , Issue.7 , pp. 991-1000
    • Bao, M.Z.1    Schwartz, M.A.2    Cantin, G.T.3    Yates III, J.R.4    Madhani, H.D.5
  • 78
    • 11244342204 scopus 로고    scopus 로고
    • Differential regulation of Tec1 by Fus3 and Kss1 confers signaling specificity in yeast development
    • Brückner, S., Köhler, T., Braus, G. H., Heise, B., Bolte, M., and Mösch, H. U. (2004) Differential regulation of Tec1 by Fus3 and Kss1 confers signaling specificity in yeast development. Curr. Genet. 46, 331-342
    • (2004) Curr. Genet. , vol.46 , pp. 331-342
    • Brückner, S.1    Köhler, T.2    Braus, G.H.3    Heise, B.4    Bolte, M.5    Mösch, H.U.6
  • 79
    • 3342900058 scopus 로고    scopus 로고
    • Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes
    • DOI 10.1038/sj.emboj.7600250
    • Andersson, J., Simpson, D. M., Qi, M., Wang, Y., and Elion, E. A. (2004) Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes. EMBO J. 23, 2564-2576 (Pubitemid 38988228)
    • (2004) EMBO Journal , vol.23 , Issue.13 , pp. 2564-2576
    • Andersson, J.1    Simpson, D.M.2    Qi, M.3    Wang, Y.4    Elion, E.A.5
  • 80
    • 0030731714 scopus 로고    scopus 로고
    • MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation
    • Madhani, H. D., Styles, C. A., and Fink, G. R. (1997) MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation. Cell 91, 673-684 (Pubitemid 27513658)
    • (1997) Cell , vol.91 , Issue.5 , pp. 673-684
    • Madhani, H.D.1    Styles, C.A.2    Fink, G.R.3
  • 81
    • 84860427832 scopus 로고    scopus 로고
    • Ubiquitin and its binding domains
    • Randles, L., and Walters, K. J. (2012) Ubiquitin and its binding domains. Front. Biosci. 17, 2140-2157
    • (2012) Front. Biosci. , vol.17 , pp. 2140-2157
    • Randles, L.1    Walters, K.J.2
  • 82
    • 11144340454 scopus 로고    scopus 로고
    • Cdc4 determines MAPK signaling specificity during mating in yeast
    • DOI 10.1016/j.cell.2004.11.053, PII S0092867404011663
    • Chou, S., Huang, L., and Liu, H. (2004) Fus3-regulated Tec1 degradation through SCFCdc4 determines MAPK signaling specificity during mating in yeast. Cell 119, 981-990 (Pubitemid 40037611)
    • (2004) Cell , vol.119 , Issue.7 , pp. 981-990
    • Chou, S.1    Huang, L.2    Liu, H.3
  • 83
    • 33751261134 scopus 로고    scopus 로고
    • Mechanisms of MAPK signalling specificity
    • Bardwell, L. (2006) Mechanisms of MAPK signalling specificity. Biochem. Soc. Trans. 34, 837-841
    • (2006) Biochem. Soc. Trans. , vol.34 , pp. 837-841
    • Bardwell, L.1
  • 84
    • 33746061228 scopus 로고    scopus 로고
    • Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain
    • DOI 10.1101/gad.1413706
    • Garrenton, L. S., Young, S. L., and Thorner, J. (2006) Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain. Genes Dev. 20, 1946-1958 (Pubitemid 44079331)
    • (2006) Genes and Development , vol.20 , Issue.14 , pp. 1946-1958
    • Garrenton, L.S.1    Young, S.L.2    Thorner, J.3
  • 85
    • 25844442435 scopus 로고    scopus 로고
    • A membrane binding domain in the Ste5 scaffold synergizes with Gβγ binding to control localization and signaling in pheromone response
    • DOI 10.1016/j.molcel.2005.08.020, PII S1097276505015625
    • Winters, M. J., Lamson, R. E., Nakanishi, H., Neiman, A. M., and Pryciak, P. M. (2005) A membrane binding domain in the ste5 scaffold synergizes with Gβγ binding to control localization and signaling in pheromone response. Mol. Cell 20, 21-32 (Pubitemid 41396559)
    • (2005) Molecular Cell , vol.20 , Issue.1 , pp. 21-32
    • Winters, M.J.1    Lamson, R.E.2    Nakanishi, H.3    Neiman, A.M.4    Pryciak, P.M.5
  • 86
    • 77955370261 scopus 로고    scopus 로고
    • Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling
    • Garrenton, L. S., Stefan, C. J., McMurray, M. A., Emr, S. D., and Thorner, J. (2010) Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling. Proc. Natl. Acad. Sci. U.S.A. 107, 11805-11810
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 11805-11810
    • Garrenton, L.S.1    Stefan, C.J.2    McMurray, M.A.3    Emr, S.D.4    Thorner, J.5
  • 87
    • 79955432520 scopus 로고    scopus 로고
    • Selective regulation of MAP kinase signaling by an endomembrane phosphatidylinositol 4-kinase
    • Cappell, S. D., and Dohlman, H. G. (2011) Selective regulation of MAP kinase signaling by an endomembrane phosphatidylinositol 4-kinase. J. Biol. Chem. 286, 14852-14860
    • (2011) J. Biol. Chem. , vol.286 , pp. 14852-14860
    • Cappell, S.D.1    Dohlman, H.G.2
  • 88
    • 33745685061 scopus 로고    scopus 로고
    • Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein α subunit at the endosome
    • Slessareva, J. E., Routt, S. M., Temple, B., Bankaitis, V. A., and Dohlman, H. G. (2006) Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein α subunit at the endosome. Cell 126, 191-203
    • (2006) Cell , vol.126 , pp. 191-203
    • Slessareva, J.E.1    Routt, S.M.2    Temple, B.3    Bankaitis, V.A.4    Dohlman, H.G.5
  • 89
    • 28344456279 scopus 로고    scopus 로고
    • A genomic and functional inventory of deubiquitinating enzymes
    • DOI 10.1016/j.cell.2005.11.007, PII S0092867405011694
    • Nijman, S. M., Luna-Vargas, M. P., Velds, A., Brummelkamp, T. R., Dirac, A. M., Sixma, T. K., and Bernards, R. (2005) A genomic and functional inventory of deubiquitinating enzymes. Cell 123, 773-786 (Pubitemid 41721026)
    • (2005) Cell , vol.123 , Issue.5 , pp. 773-786
    • Nijman, S.M.B.1    Luna-Vargas, M.P.A.2    Velds, A.3    Brummelkamp, T.R.4    Dirac, A.M.G.5    Sixma, T.K.6    Bernards, R.7
  • 90
    • 0037401872 scopus 로고    scopus 로고
    • Deubiquitinating enzymes - The importance of driving in reverse along the ubiquitin-proteasome pathway
    • Wing, S. S. (2003) Deubiquitinating enzymes-the importance of driving in reverse along the ubiquitin-proteasome pathway. Int. J. Biochem. Cell Biol. 35, 590-605
    • (2003) Int. J. Biochem. Cell Biol. , vol.35 , pp. 590-605
    • Wing, S.S.1
  • 91
    • 0028823598 scopus 로고
    • Metabolism of the polyubiquitin degradation signal: Structure, mechanism, and role of isopeptidase T
    • Wilkinson, K. D., Tashayev, V. L., O'Connor, L. B., Larsen, C. N., Kasperek, E., and Pickart, C. M. (1995) Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T. Biochemistry 34, 14535-14546
    • (1995) Biochemistry , vol.34 , pp. 14535-14546
    • Wilkinson, K.D.1    Tashayev, V.L.2    O'Connor, L.B.3    Larsen, C.N.4    Kasperek, E.5    Pickart, C.M.6
  • 92
    • 68049084674 scopus 로고    scopus 로고
    • Breaking the chains: Structure and function of the deubiquitinases
    • Komander, D., Clague, M. J., and Urbé, S. (2009) Breaking the chains: structure and function of the deubiquitinases. Nat. Rev. Mol. Cell Biol. 10, 550-563
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 550-563
    • Komander, D.1    Clague, M.J.2    Urbé, S.3
  • 94
    • 78549277226 scopus 로고    scopus 로고
    • Yeast deubiquitinase Ubp3 interacts with the 26 S proteasome to facilitate Rad4 degradation
    • Mao, P., and Smerdon, M. J. (2010) Yeast deubiquitinase Ubp3 interacts with the 26 S proteasome to facilitate Rad4 degradation. J. Biol. Chem. 285, 37542-37550
    • (2010) J. Biol. Chem. , vol.285 , pp. 37542-37550
    • Mao, P.1    Smerdon, M.J.2
  • 95
    • 70449382789 scopus 로고    scopus 로고
    • Sumoylation of transcription factor Tec1 regulates signaling of mitogen-activated protein kinase pathways in yeast
    • Wang, Y., Abu Irqeba, A., Ayalew, M., and Suntay, K. (2009) Sumoylation of transcription factor Tec1 regulates signaling of mitogen-activated protein kinase pathways in yeast. PLoS One 4, e7456
    • (2009) PLoS One , vol.4
    • Wang, Y.1    Abu Irqeba, A.2    Ayalew, M.3    Suntay, K.4
  • 96
    • 0028670651 scopus 로고
    • Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: Mating and invasive growth
    • Roberts, R. L., and Fink, G. R. (1994) Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth. Genes Dev. 8, 2974-2985
    • (1994) Genes Dev. , vol.8 , pp. 2974-2985
    • Roberts, R.L.1    Fink, G.R.2
  • 97
    • 0031042444 scopus 로고    scopus 로고
    • Combinatorial control required for the specificity of yeast MAPK signaling
    • Madhani, H. D., and Fink, G. R. (1997) Combinatorial control required for the specificity of yeast MAPK signaling. Science 275, 1314-1317
    • (1997) Science , vol.275 , pp. 1314-1317
    • Madhani, H.D.1    Fink, G.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.