메뉴 건너뛰기




Volumn 1, Issue 2, 1998, Pages 175-182

Signal transduction by MAP kinase cascades in budding yeast

Author keywords

[No Author keywords available]

Indexed keywords

PROKARYOTA; SACCHAROMYCETALES;

EID: 0032035043     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(98)80008-8     Document Type: Article
Times cited : (142)

References (66)
  • 1
    • 0028152333 scopus 로고
    • MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
    • Marshall CJ: MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr Opin Genet Dev 1994, 4:82-89.
    • (1994) Curr Opin Genet Dev , vol.4 , pp. 82-89
    • Marshall, C.J.1
  • 2
    • 0029043582 scopus 로고    scopus 로고
    • How MAP kinases are regulated
    • Cobb MH, Goldsmith EJ: How MAP kinases are regulated. J Biol Chem 1996, 270:14843-14846.
    • (1996) J Biol Chem , vol.270 , pp. 14843-14846
    • Cobb, M.H.1    Goldsmith, E.J.2
  • 3
    • 0028823892 scopus 로고
    • Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast
    • Waskiewicz AJ, Cooper JA: Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast. Curr Opin Cell Biol 1995, 7:798-805.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 798-805
    • Waskiewicz, A.J.1    Cooper, J.A.2
  • 4
    • 0029790351 scopus 로고    scopus 로고
    • Ultrasensitivity in the mitogen-activated protein kinase cascade
    • Huang CY, Ferrell JEJ: Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 1996, 93:10078-10083.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10078-10083
    • Huang, C.Y.1    Ferrell, J.E.J.2
  • 5
    • 0027144459 scopus 로고
    • The pheromone response pathway in Saccharomyces cerevisiae
    • Kurjan J: The pheromone response pathway in Saccharomyces cerevisiae. Annu Rev Genet 1993, 27:147-179.
    • (1993) Annu Rev Genet , vol.27 , pp. 147-179
    • Kurjan, J.1
  • 6
    • 0028985079 scopus 로고
    • MAP kinase pathways in yeast: For mating and more
    • Herskowitz I: MAP kinase pathways in yeast: for mating and more. Cell 1995, 80:187-197.
    • (1995) Cell , vol.80 , pp. 187-197
    • Herskowitz, I.1
  • 7
    • 0029914238 scopus 로고    scopus 로고
    • Plugging it in; signaling circuits and the yeast cell cycle
    • Wittenberg C, Reed SI: Plugging it in; signaling circuits and the yeast cell cycle. Curr Opin Cell Biol 1996, 8:223-230.
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 223-230
    • Wittenberg, C.1    Reed, S.I.2
  • 8
    • 0027983908 scopus 로고
    • Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae
    • Choi KY, Satterberg B, Lyons DM, Elion EA: Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae. Cell 1994, 78:499-512.
    • (1994) Cell , vol.78 , pp. 499-512
    • Choi, K.Y.1    Satterberg, B.2    Lyons, D.M.3    Elion, E.A.4
  • 9
    • 0028057744 scopus 로고
    • The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5
    • Kranz JE, Satterberg B, Elion EA: The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5. Genes Dev 1994, 8:313-327.
    • (1994) Genes Dev , vol.8 , pp. 313-327
    • Kranz, J.E.1    Satterberg, B.2    Elion, E.A.3
  • 10
    • 0027991228 scopus 로고
    • Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module
    • Marcus S, Polverino A, Barr W, Wigler M: Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module. Proc Natl Acad Sci USA 1994, 91:7762-7766.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7762-7766
    • Marcus, S.1    Polverino, A.2    Barr, W.3    Wigler, M.4
  • 11
    • 0028046412 scopus 로고
    • Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade
    • Printen JA, Sprague GF: Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade. Genetics 1994, 138:609-619.
    • (1994) Genetics , vol.138 , pp. 609-619
    • Printen, J.A.1    Sprague, G.F.2
  • 12
    • 0027253814 scopus 로고
    • FUS3 phosphorylates multiple components of the mating signal transduction cascade: Evidence for STE12 and FAR1
    • Elion EA, Satterberg B, Kranz JE: FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1. Mol Biol Cell 1993, 4:495-510.
    • (1993) Mol Biol Cell , vol.4 , pp. 495-510
    • Elion, E.A.1    Satterberg, B.2    Kranz, J.E.3
  • 13
    • 0027191189 scopus 로고
    • FAR1 protein links the signal transduction pathway to the cell cycle machinery in yeast
    • Peter M, Gartner A, Horecka J, Ammerer G, Herskowitz I: FAR1 protein links the signal transduction pathway to the cell cycle machinery in yeast. Cell 1993, 73:747-760.
    • (1993) Cell , vol.73 , pp. 747-760
    • Peter, M.1    Gartner, A.2    Horecka, J.3    Ammerer, G.4    Herskowitz, I.5
  • 14
    • 0028085427 scopus 로고
    • Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1
    • Peter M, Herskowitz I: Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1. Science 1994, 265:1228-1231.
    • (1994) Science , vol.265 , pp. 1228-1231
    • Peter, M.1    Herskowitz, I.2
  • 15
    • 0029146796 scopus 로고
    • Association of the yeast pheromone response G protein βγ subunits with the MAP kinase scaffold Ste5p
    • Whiteway MS, Wu C, Leeuw T, Clark K, Fourest-Lieuvin A, Thomas DY, Leberer E: Association of the yeast pheromone response G protein βγ subunits with the MAP kinase scaffold Ste5p. Science 1995, 269:1572-1575.
    • (1995) Science , vol.269 , pp. 1572-1575
    • Whiteway, M.S.1    Wu, C.2    Leeuw, T.3    Clark, K.4    Fourest-Lieuvin, A.5    Thomas, D.Y.6    Leberer, E.7
  • 16
    • 0030815533 scopus 로고    scopus 로고
    • Ste5 RING-H2 domain: Role in Ste4-promoted oligomerization for yeast pheromone signaling
    • Inouye C, Dhillon N, Thorner J: Ste5 RING-H2 domain: role in Ste4-promoted oligomerization for yeast pheromone signaling. Science 1997, 278:103-106. In this paper, the authors report that the RING-H2 domain at the amino terminus of Ste5 is essential for its function because mutations of this domain (C177S or C177S C180S) cannot rescue the mating defects of ste5D cells. Such Ste5 mutant proteins still bind to each component of the mating-pheromone MAPK cascade but do not bind to Gβ (Ste4). The authors conclude that the Ste5 oligomerization induced by Ste5-Ste4 interaction is essential for signal transduction.
    • (1997) Science , vol.278 , pp. 103-106
    • Inouye, C.1    Dhillon, N.2    Thorner, J.3
  • 17
    • 0030450397 scopus 로고    scopus 로고
    • Dimerization of Ste5, a mitogen-activated protein kinase cascade scaffold protein, is required for signal transduction
    • Yablonski D, Marbach I, Levitzki A: Dimerization of Ste5, a mitogen-activated protein kinase cascade scaffold protein, is required for signal transduction. Proc Natl Acad Sci USA 1996, 93:13864-13869. This paper, as with Inouye et al., 1997 [16•], reports that Ste5 dimerization is essential for Ste5 function. Dimerization of Ste5, mediated by two regions in the Ste5 aminoterminal half, is suggested by intragenic complementation between pairs of nonfunctional Ste5 mutants, by two-hybrid analysis, and by co-precipitation experiments.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13864-13869
    • Yablonski, D.1    Marbach, I.2    Levitzki, A.3
  • 18
    • 0029118202 scopus 로고
    • Pheromone signalling in Saccharomyces cerevisiae requires the small GTP-binding protein Cdc42p and its activator CDC24
    • Zhao Z-S, Leung T, Manser E, Lim L: Pheromone signalling in Saccharomyces cerevisiae requires the small GTP-binding protein Cdc42p and its activator CDC24. Mot Cell Biol 1995, 15:5246-5257.
    • (1995) Mot Cell Biol , vol.15 , pp. 5246-5257
    • Zhao, Z.-S.1    Leung, T.2    Manser, E.3    Lim, L.4
  • 19
    • 0029157469 scopus 로고
    • Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway
    • Simon MN, De Virgilio C, Souza B, Pringle JR, Abo A, Reed SI: Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway. Nature 1995, 376:702-705.
    • (1995) Nature , vol.376 , pp. 702-705
    • Simon, M.N.1    De Virgilio, C.2    Souza, B.3    Pringle, J.R.4    Abo, A.5    Reed, S.I.6
  • 20
    • 0030465534 scopus 로고    scopus 로고
    • Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast
    • Peter M, Neiman AM, Park H-O, van Lohuizen M, Herskowitz I: Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast. EMBO J 1996, 15:7046-7059. See annotation [21•].
    • (1996) EMBO J , vol.15 , pp. 7046-7059
    • Peter, M.1    Neiman, A.M.2    Park, H.-O.3    Van Lohuizen, M.4    Herskowitz, I.5
  • 21
    • 0031015562 scopus 로고    scopus 로고
    • Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase
    • Leberer E, Wu C, Leeuw T, Fourest-Lieuvin A, Segall JE, Thomas DY: Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase. EMBO J 1997, 15:83-97. This paper and that of Peter et al., 1996 [20•] reached the same essential conclusions: Cdc42 binds to the amino-terminal region of Ste20, and Cdc42 binding to Ste20 is essential for the vegetative function of Ste20 as well as for the activation of the pseudohyphal/invasive growth pathway. In contrast, Ste20 mutants that do not bind Cdc42 can still activate the mating pheromone MAPK cascade. Cdc42 is required, however, for efficient mating in order to facilitate the cell-cell adhesion during conjugation by properly localizing Ste20 at shmoo tips.
    • (1997) EMBO J , vol.15 , pp. 83-97
    • Leberer, E.1    Wu, C.2    Leeuw, T.3    Fourest-Lieuvin, A.4    Segall, J.E.5    Thomas, D.Y.6
  • 23
    • 0029892972 scopus 로고    scopus 로고
    • The SH3-domain protein Bem1 coordinates mitogen-activated protein kinase cascade activation with cell cycle control in Saccharomyces cerevisiae
    • Lyons DM, Mahanty SK, Choi K-Y, Manandhar W, Elion EA: The SH3-domain protein Bem1 coordinates mitogen-activated protein kinase cascade activation with cell cycle control in Saccharomyces cerevisiae. Mol Cell Biol 1996, 16:4095-4106.
    • (1996) Mol Cell Biol , vol.16 , pp. 4095-4106
    • Lyons, D.M.1    Mahanty, S.K.2    Choi, K.-Y.3    Manandhar, W.4    Elion, E.A.5
  • 24
    • 0026588787 scopus 로고
    • Unipolar cell divisions in the yeast Saccharomyces lead to filamentous growth: Regulation by starvation and RAS
    • Gimeno CM, Ljungdahl PO, Styles CA, Fink GR: Unipolar cell divisions in the yeast Saccharomyces lead to filamentous growth: regulation by starvation and RAS. Cell 1992, 68:1077-1090.
    • (1992) Cell , vol.68 , pp. 1077-1090
    • Gimeno, C.M.1    Ljungdahl, P.O.2    Styles, C.A.3    Fink, G.R.4
  • 25
    • 0028670651 scopus 로고
    • Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: Mating and invasive growth
    • Roberts RL, Fink GR: Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth. Genes Dev 1994, 8:2974-2985.
    • (1994) Genes Dev , vol.8 , pp. 2974-2985
    • Roberts, R.L.1    Fink, G.R.2
  • 26
    • 0027759277 scopus 로고
    • Elements of the yeast pheromone response pathway required for filamentous growth of diploids
    • Liu H, Styles CA, Fink GR: Elements of the yeast pheromone response pathway required for filamentous growth of diploids. Science 1993, 262:1741-1744.
    • (1993) Science , vol.262 , pp. 1741-1744
    • Liu, H.1    Styles, C.A.2    Fink, G.R.3
  • 28
    • 0031587849 scopus 로고    scopus 로고
    • 14-3-3 proteins are essential for RAS/MAPK cascade signaling during pseudohyphal development in S. cerevisiae
    • Roberts RL, Mösch H-U, Fink GR: 14-3-3 proteins are essential for RAS/MAPK cascade signaling during pseudohyphal development in S. cerevisiae. Cell 1997, 89:1055-1065.
    • (1997) Cell , vol.89 , pp. 1055-1065
    • Roberts, R.L.1    Mösch, H.-U.2    Fink, G.R.3
  • 29
    • 0030731714 scopus 로고    scopus 로고
    • MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation
    • Madhani HD, Styles CA, Fink GR: MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation. Cell 1997, 91:673-684. See annotation [30••].
    • (1997) Cell , vol.91 , pp. 673-684
    • Madhani, H.D.1    Styles, C.A.2    Fink, G.R.3
  • 30
    • 0030688862 scopus 로고    scopus 로고
    • Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway
    • Cook JG, Bardwell L, Thorner J: Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway. Nature 1997, 390:85-88. Data in this paper and [29•] suggest that the Fus3 MAPK mainly regulates mating whereas the Kss1 MAPK regulates filamentation and invasive growth. In addition to their kinase-dependent activities, Fus3 and Kss1 have distinct kinase-independent inhibitory functions; inactive Kss1 interacts with and inhibits Ste12, whereas both inactive and active Fus3 prevent invasive growth.
    • (1997) Nature , vol.390 , pp. 85-88
    • Cook, J.G.1    Bardwell, L.2    Thorner, J.3
  • 31
    • 0029804618 scopus 로고    scopus 로고
    • Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae
    • Cook JG, Bardwell L, Kron SJ, Thorner J: Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes Dev 1996, 10:2831-2848.
    • (1996) Genes Dev , vol.10 , pp. 2831-2848
    • Cook, J.G.1    Bardwell, L.2    Kron, S.J.3    Thorner, J.4
  • 32
    • 0031128205 scopus 로고    scopus 로고
    • Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates
    • Tedford K, Kim S, Sa D, Stevens K, Tyers M: Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates. Curr Biol 1997, 7:228-238.
    • (1997) Curr Biol , vol.7 , pp. 228-238
    • Tedford, K.1    Kim, S.2    Sa, D.3    Stevens, K.4    Tyers, M.5
  • 33
    • 0025998311 scopus 로고
    • FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction
    • Elion EA, Brill JA, Fink GR: FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction. Proc Natl Acad Sci USA 1991, 88:9392-9396.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 9392-9396
    • Elion, E.A.1    Brill, J.A.2    Fink, G.R.3
  • 35
    • 0029832793 scopus 로고    scopus 로고
    • Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development
    • Köhler JR, Fink GR: Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development. Proc Natl Acad Sci USA 1996, 93:13223-13228.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13223-13228
    • Köhler, J.R.1    Fink, G.R.2
  • 37
    • 0028920365 scopus 로고
    • The proliferation of MAP kinase signaling pathways in yeast
    • Levin DE, Errede B: The proliferation of MAP kinase signaling pathways in yeast. Curr Opin Cell Biol 1995, 7:197-202.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 197-202
    • Levin, D.E.1    Errede, B.2
  • 38
    • 0029561101 scopus 로고
    • A second osmosensing signal transduction pathway in yeast: Hypotonic shock activates the PKC1 protein kinase-regulated cell integrity pathway
    • Davenport KR, Sohaskey M, Kamada Y, Levin DE, Gustin MC: A second osmosensing signal transduction pathway in yeast: hypotonic shock activates the PKC1 protein kinase-regulated cell integrity pathway. J Biol Chem 1995, 270:30157-30161.
    • (1995) J Biol Chem , vol.270 , pp. 30157-30161
    • Davenport, K.R.1    Sohaskey, M.2    Kamada, Y.3    Levin, D.E.4    Gustin, M.C.5
  • 39
    • 11944273348 scopus 로고
    • The protein kinase C-activated MAP kinase pathway in Saccharomyces cerevisiae mediates a novel aspect of the heat shock response
    • Kamada Y, Jung US, Piotrowski J, Levin DE: The protein kinase C-activated MAP kinase pathway in Saccharomyces cerevisiae mediates a novel aspect of the heat shock response. Genes Dev 1995, 9:1559-1571.
    • (1995) Genes Dev , vol.9 , pp. 1559-1571
    • Kamada, Y.1    Jung, U.S.2    Piotrowski, J.3    Levin, D.E.4
  • 40
    • 0028829555 scopus 로고
    • A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae
    • Nonaka H, Tanaka K, Hirano H, Fujiwara T, Kohno H, Umikawa M, Mino A, Takai Y: A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae. EMBO J 1995, 14:5931-5938.
    • (1995) EMBO J , vol.14 , pp. 5931-5938
    • Nonaka, H.1    Tanaka, K.2    Hirano, H.3    Fujiwara, T.4    Kohno, H.5    Umikawa, M.6    Mino, A.7    Takai, Y.8
  • 41
    • 0029922871 scopus 로고    scopus 로고
    • Activation of yeast protein kinase C by Rho1 GTPase
    • Kamada Y, Qadota H, Python CP, Anraku Y, Ohya Y, Levin DE: Activation of yeast protein kinase C by Rho1 GTPase. J Biol Chem 1996, 271:9193-9196. The authors of this paper describe the direct involvement of the Rho1 GTPase in Pkc1 activation. The GTP-bound form of Rho1 confers on Pkc1 the ability to be activated by the cafactor phosphatidylserine. This provides a potential mechanism to regulate the activity of the PKC pathway by cytoskeletal reorganization and membrane alterations.
    • (1996) J Biol Chem , vol.271 , pp. 9193-9196
    • Kamada, Y.1    Qadota, H.2    Python, C.P.3    Anraku, Y.4    Ohya, Y.5    Levin, D.E.6
  • 42
    • 0029920783 scopus 로고    scopus 로고
    • Rom1p and Rom2p are GDP/GTP exchange proteins (GEFs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae
    • Ozaki K, Tanaka K, Imamura H, Hihara T, Kameyama T, Nonaka H, Hirano H, Matsuura Y, Takai Y: Rom1p and Rom2p are GDP/GTP exchange proteins (GEFs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae. EMBO J 1996, 15:2196-2207.
    • (1996) EMBO J , vol.15 , pp. 2196-2207
    • Ozaki, K.1    Tanaka, K.2    Imamura, H.3    Hihara, T.4    Kameyama, T.5    Nonaka, H.6    Hirano, H.7    Matsuura, Y.8    Takai, Y.9
  • 43
    • 0030906569 scopus 로고    scopus 로고
    • The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2
    • Schmidt A, Bickle M, Beck T, Hall MN: The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2. Cell 1997, 88:531-542.
    • (1997) Cell , vol.88 , pp. 531-542
    • Schmidt, A.1    Bickle, M.2    Beck, T.3    Hall, M.N.4
  • 45
    • 0029892037 scopus 로고    scopus 로고
    • Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-β-glucan synthase
    • Qadota H, Python CP, Inoue SB, Arisawa M, Anraku Y, Zheng Y, Watanabe T, Levin DE, Ohya Y: Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-β-glucan synthase. Science 1996, 272:279-281. This paper and that of Drgonová et al., 1996 [44•] demonstrated that the small GTPase Rho1 is a regulatory subunit of the 1,3-β-glucan synthase complex. 1,3-β-linked glucan is a major structural component of the yeast cell wall and Rho1 is localized predominantly at sites of cell wall remodeling.
    • (1996) Science , vol.272 , pp. 279-281
    • Qadota, H.1    Python, C.P.2    Inoue, S.B.3    Arisawa, M.4    Anraku, Y.5    Zheng, Y.6    Watanabe, T.7    Levin, D.E.8    Ohya, Y.9
  • 46
    • 0030789480 scopus 로고    scopus 로고
    • A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator
    • 1/S transition. This paper also suggests that a type I transmembrane protein, Hcs77, may monitor the integrity of the cell surface, and activate PKC pathway upon heat shock.
    • (1997) EMBO J , vol.16 , pp. 4929-4937
    • Gray, J.V.1    Ogas, J.P.2    Kamada, Y.3    Stone, M.4    Levin, D.E.5    Herskowitz, I.6
  • 47
    • 0030007679 scopus 로고    scopus 로고
    • A pathway in the yeast cell division cycle linking protein kinase C (Pkc1) to activation of Cdc28 at START
    • 1/S transition. These authors further propose that the increased production of diacylglycerol mediated by the Cdc28-dependent phosphatidylcholine-specific phosphotipase C may be responsible for Pkc1 activation.
    • (1996) EMBO J , vol.15 , pp. 3040-3052
    • Marini, N.J.1    Meldrum, B.B.2    Hubberstey, A.V.3    Stone, D.E.4    Traynor-Kaplan, A.5    Reed, S.I.6
  • 48
    • 0027979837 scopus 로고
    • A novel gene, STT4, encodes a phosphatidylinositol 4-kinase in the PKC1 protein kinase pathway in Saccharomyces cerevisiae
    • Yoshida S, Ohya Y, Goebl M, Nakano A, Anraku Y: A novel gene, STT4, encodes a phosphatidylinositol 4-kinase in the PKC1 protein kinase pathway in Saccharomyces cerevisiae. J Biol Chem 1994, 269:1166-1172.
    • (1994) J Biol Chem , vol.269 , pp. 1166-1172
    • Yoshida, S.1    Ohya, Y.2    Goebl, M.3    Nakano, A.4    Anraku, Y.5
  • 49
    • 0030799126 scopus 로고    scopus 로고
    • Coordination of the mating an cell integrity mitogen-activated protein kinase pathways in Saccharomyces cerevisiae
    • Buehrer BM, Errede B: Coordination of the mating an cell integrity mitogen-activated protein kinase pathways in Saccharomyces cerevisiae. Mol Cell Biol 1997, 17:6517-6525.
    • (1997) Mol Cell Biol , vol.17 , pp. 6517-6525
    • Buehrer, B.M.1    Errede, B.2
  • 52
    • 0028302033 scopus 로고
    • GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway
    • Albertyn J, Hohmann S, Thevelein JM, Prior BA: GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway. Mol Cell Biol 1994, 14:4135-4144.
    • (1994) Mol Cell Biol , vol.14 , pp. 4135-4144
    • Albertyn, J.1    Hohmann, S.2    Thevelein, J.M.3    Prior, B.A.4
  • 53
    • 0026443099 scopus 로고
    • PBS2, a yeast gene encoding a putative protein kinase, interacts with the RAS2 pathway and affects osmotic sensitivity of Saccharomyces cerevisiae
    • Boguslawski G: PBS2, a yeast gene encoding a putative protein kinase, interacts with the RAS2 pathway and affects osmotic sensitivity of Saccharomyces cerevisiae. J Gen Microbiol 1992, 138:2425-2432.
    • (1992) J Gen Microbiol , vol.138 , pp. 2425-2432
    • Boguslawski, G.1
  • 54
    • 0028228109 scopus 로고
    • A two-component system that regulates an osmosensing MAP kinase cascade in yeast
    • Maeda T, Wurgler-Murphy SM, Saito H: A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature 1994, 369:242-245.
    • (1994) Nature , vol.369 , pp. 242-245
    • Maeda, T.1    Wurgler-Murphy, S.M.2    Saito, H.3
  • 55
    • 0029028962 scopus 로고
    • Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor
    • Maeda T, Takekawa M, Saito H: Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor. Science 1995, 269:554-558.
    • (1995) Science , vol.269 , pp. 554-558
    • Maeda, T.1    Takekawa, M.2    Saito, H.3
  • 56
    • 0027507956 scopus 로고
    • A yeast protein similar to bacterial two-component regulators
    • Ota IM, Varshavsky A: A yeast protein similar to bacterial two-component regulators. Science 1993, 262:566-569.
    • (1993) Science , vol.262 , pp. 566-569
    • Ota, I.M.1    Varshavsky, A.2
  • 57
    • 0030595378 scopus 로고    scopus 로고
    • Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 "two-component" osmosensor
    • Posas F, Wurgler-Murphy SM, Maeda T, Witten EA, Thai TC, Saito H: Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 "two-component" osmosensor. Cell 1996, 86:865-375. This paper demonstrates that a multistep phospho-relay mechanism regulates the phosphorylation state of the Ssk1 receiver domain protein. Phosphotransfer reactions are examined both in vivo and in vitro.
    • (1996) Cell , vol.86 , pp. 865-1375
    • Posas, F.1    Wurgler-Murphy, S.M.2    Maeda, T.3    Witten, E.A.4    Thai, T.C.5    Saito, H.6
  • 58
    • 0030953080 scopus 로고    scopus 로고
    • Two-component signal transducers and MAPK cascades
    • Wurgler-Murphy SM, Saito H: Two-component signal transducers and MAPK cascades. Trends Biochem Sci 1997, 22:172-176.
    • (1997) Trends Biochem Sci , vol.22 , pp. 172-176
    • Wurgler-Murphy, S.M.1    Saito, H.2
  • 59
    • 0030815562 scopus 로고    scopus 로고
    • Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: Scaffold role of Pbs2p MAPKK
    • Posas F, Saito H: Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK. Science 1997, 276:1702-1705. This paper demonstrated that the Ste11 MAPKKK is essential for the activation of the Pbs2 MAPKK by the Sho1 osmosensor. In spile of the sharing of Ste11 by the mating and osmoregulatory pathways, there is no cross-talk between them. It is proposed that Pbs2 might function as a scaffold protein in the osmoregulatory pathway because Pbs2 binds Sho1, Ste11, and Hog1.
    • (1997) Science , vol.276 , pp. 1702-1705
    • Posas, F.1    Saito, H.2
  • 60
    • 0030927499 scopus 로고    scopus 로고
    • Activate alleles of yeast SLN1 increase Mcm1 -dependent reporter gene expression and diminish signaling through the Hog1 osmosensing pathway
    • Fassler JS, Gray WM, Malone CL, Tao W, Lin H, Deschenes RJ: Activate alleles of yeast SLN1 increase Mcm1 -dependent reporter gene expression and diminish signaling through the Hog1 osmosensing pathway. J Biol Chem 1997, 272:13365-13371.
    • (1997) J Biol Chem , vol.272 , pp. 13365-13371
    • Fassler, J.S.1    Gray, W.M.2    Malone, C.L.3    Tao, W.4    Lin, H.5    Deschenes, R.J.6
  • 61
    • 0028961046 scopus 로고
    • The essential transcription factor, Mcm1, is a downstream target of Sln1, a yeast "two-component" regulator
    • Yu G, Deschenes RJ, Fassler JS: The essential transcription factor, Mcm1, is a downstream target of Sln1, a yeast "two-component" regulator. J Biol Chem 1995, 270:8739-8743.
    • (1995) J Biol Chem , vol.270 , pp. 8739-8743
    • Yu, G.1    Deschenes, R.J.2    Fassler, J.S.3
  • 62
    • 0027940655 scopus 로고
    • SH2 and SH3 domains as molecular adhesives: The interactions of Crk and Ab1
    • Feller SM, Ren R, Hanafusa H, Baltimore D: SH2 and SH3 domains as molecular adhesives: the interactions of Crk and Ab1. Trends Biochem Sci 1994, 19:453-458.
    • (1994) Trends Biochem Sci , vol.19 , pp. 453-458
    • Feller, S.M.1    Ren, R.2    Hanafusa, H.3    Baltimore, D.4
  • 63
    • 0031027466 scopus 로고    scopus 로고
    • Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases
    • Wurgler-Murphy SM, Maeda T, Witten EA, Saito H: Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases. Mol Cell Biol 1997, 17:1289-1297.
    • (1997) Mol Cell Biol , vol.17 , pp. 1289-1297
    • Wurgler-Murphy, S.M.1    Maeda, T.2    Witten, E.A.3    Saito, H.4
  • 64
    • 0027202272 scopus 로고
    • Mutations in a protein tyrosine phosphatase gene (PTP2) and a protein serine/threonine phosphatase gene (PTC1) cause a synthetic growth defect in Saccharomyces cerevisiae
    • Maeda T, Tsai AYM, Saito H: Mutations in a protein tyrosine phosphatase gene (PTP2) and a protein serine/threonine phosphatase gene (PTC1) cause a synthetic growth defect in Saccharomyces cerevisiae. Mol Cell Biol 1993, 13:5409-5417.
    • (1993) Mol Cell Biol , vol.13 , pp. 5409-5417
    • Maeda, T.1    Tsai, A.Y.M.2    Saito, H.3
  • 65
    • 0030820725 scopus 로고    scopus 로고
    • Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae
    • Zhan X-L, Deschenes RJ, Guan K-L: Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae. Genes Dev 1997, 11:1690-1702.
    • (1997) Genes Dev , vol.11 , pp. 1690-1702
    • Zhan, X.-L.1    Deschenes, R.J.2    Guan, K.-L.3
  • 66
    • 0028157519 scopus 로고
    • MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae
    • Doi K, Gartner A, Ammerer G, Errede B, Shinkawa H, Sugimolo K, Matsumoto K: MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae. EMBO J 1994, 13:61-70.
    • (1994) EMBO J , vol.13 , pp. 61-70
    • Doi, K.1    Gartner, A.2    Ammerer, G.3    Errede, B.4    Shinkawa, H.5    Sugimolo, K.6    Matsumoto, K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.