Hydrolysis of extracellular ATP by ectonucleoside triphosphate diphosphohydrolase (ENTPD) establishes the set point for fibrotic activity of cardiac fibroblasts

Journal of Biological Chemistry

Volumn 288, Issue 26, 2013, Pages 19040-19049

  Lu, David ^a   Insel, Paul A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC FIBROBLASTS; CELLULAR ACTIVITIES; CELLULAR HOMEOSTASIS; COLLAGEN SYNTHESIS; EXTRACELLULAR ATP; PLASMINOGEN ACTIVATOR INHIBITOR-1; SMOOTH MUSCLE ACTINS; TRANSFORMING GROWTH FACTORS;

CELL CULTURE; FIBROBLASTS; PHYSIOLOGY; PROTEINS; RATS;

HYDROLYSIS;

ADENOSINE; ADENOSINE A2B RECEPTOR; ADENOSINE TRIPHOSPHATE; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHORYLASE 1; ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHORYLASE 2; PHOSPHORYLASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME INHIBITION; EXTRACELLULAR SPACE; FIBROBLAST; GENE SILENCING; HEART FIBROBLAST; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HYDROLYSIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ADENOSINE RECEPTOR; ATPASES; ENTPD; FIBROBLAST; MYOFIBROBLAST; P2Y; PURINERGIC RECEPTOR;

ADENOSINE; ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIGENS, CD; APYRASE; COLLAGEN; FIBROBLASTS; FIBROSIS; GENE KNOCKDOWN TECHNIQUES; HOMEOSTASIS; HYDROLYSIS; MALE; MYOCARDIUM; PHENOTYPE; PHOSPHORYLATION; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

RATTUS;

EID: 84879593158     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.466102     Document Type: Article

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