Inhibitory effects of oleanane-type triterpenes and saponins from the stem bark of Kalopanax pictus on LPS-stimulated pro-inflammatory cytokine production in bone marrow-derived dendritic cells

Archives of Pharmacal Research

Volumn 36, Issue 3, 2013, Pages 327-334

  Quang, Tran Hong ^a,b   Ngan, Nguyen Thi Thanh ^a   Van Minh, Chau ^b   Van Kiem, Phan ^b   Nhiem, Nguyen Xuan ^a,b   Tai, Bui Huu ^a,b   Thao, Nguyen Phuong ^a,b   Chae, Doobyeong ^c   Mathema, Vivek Bhakta ^c   Koh, Young Sang ^c   Lee, Je Hyun ^d   Yang, Seo Young ^a   Kim, Young Ho ^a  

^a Chungnam National University   (South Korea)

^b GRADUATE UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Viet Nam)

^c Jeju National University   (South Korea)

^d Dongguk University   (South Korea)

Author keywords

Araliaceae; IL 12 p40; IL 6; Kalopanax pictus; LPS stimulated BMDC; Oleanane type triterpene; TNF

Indexed keywords

16,23,29 TRIHYDROXY 3 OXO OLEAN 12 EN 28 OIC ACID; 3 O [2,3 DI O ACETYL ALPHA LEVO ARABINOPYRANOSYL]HEDERAGENIN 28 O ALPHA LEVO RHAMNOPYRANOSYL (1-4) BETA DEXTRO GLUCOPYRANOSYL (1-4) BETA DEXTRO GLUCOPYRANOSIDE; 3 O [3,4 DI O ACETYL ALPHA LEVO ARABINOPYRANOSYL]HEDERAGENIN 28 O ALPHA LEVO RHAMNOPYRANOSYL (1-4) BETA DEXTRO GLUCOPYRANOSYL (1-6) BETA DEXTRO GLUCOPYRANOSIDE; 3 O BETA DEXTRO GALACTOPYRANOSYL (1-3) ALPHA LEVO ARABINOPYRANOSYLHEDERAGENIN 28 O BETA DEXTRO GLUCOPYRANOSYL (1-6) BETA DEXTRO GLUCOPYRANOSYL ESTER; 3 O BETA DEXTRO GLUCURONOPYRANOSYL 28 O BETA DEXTRO GLUCOPYRANOSYL 6BETA,16ALPHA DIHYDROXYOLEANOLIC ACID; 3BETA,6BETA,23 TRIHYDROXYOLEAN 12 EN 28 OIC ACID; 3BETA,6BETA,23 TRIHYDROXYOLEAN 12 EN 28 OIC ACID 28 O BETA DEXTRO GLUCOPYRANOSIDE; 3BETA,6BETA,23 TRIHYDROXYOLEAN 12 EN 28 OIC ACID 3 O ALPHA LEVO ARABINOPYRANOSIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4,23,29 TRIHYDROXY 3,4 SECO OLEAN 12 EN 3 OATE 28 OIC ACID; 6BETA,16ALPHA DIHYDROXYHEDERAGENIN 3 O BETA DEXTRO GLUCURONOPYRANOSIDE; CAULOPHYLLOGENIN; CAULOSIDE D; CUSSONOSIDE A; CUSSONOSIDE B; DIPSACUSSAPONIN A; HEDERAGENIN; HEDERAGENIN 28 O BETA DEXTRO GLUCOPYRANOSYL ESTER; HEDERAGENIN 3 O ALPHA LEVO ARABINOPYRANOSIDE; INTERLEUKIN 12P40; INTERLEUKIN 6; KALOPANAXSAPONIN A; KALOPANAXSAPONIN B; KALOPANAXSAPONIN L; NIPPONOGENIN E; OLEANOLIC ACID DERIVATIVE; SAPINDOSIDE B; SAPONIN DERIVATIVE; TRITERPENE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARALIACEAE; ARTICLE; BARK; BONE MARROW CELL; CELL STRAIN HEPG2; CELL VIABILITY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXICITY; DENDRITIC CELL; DRUG EFFECT; DRUG INHIBITION; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; GENE EXPRESSION; IC 50; KALOPANAX PICTUS; MOUSE; NONHUMAN; PLANT STEM; PROTEIN EXPRESSION;

ANIMALS; BONE MARROW; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; INFLAMMATION MEDIATORS; KALOPANAX; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; OLEANOLIC ACID; PLANT BARK; PLANT EXTRACTS; SAPONINS;

EID: 84879554358     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-013-0031-8     Document Type: Article

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