In vitro antiinflammatory activity of kalopanaxsaponin A isolated from Kalopanax pictus in murine macrophage RAW 264.7 cells

Biological and Pharmaceutical Bulletin

Volumn 25, Issue 4, 2002, Pages 472-476

  Kim, Young Kwan ^a   Kim, Ryung Gue ^a   Park, So Jung ^a   Joo Hun, H A ^b   Choi, Jong Won ^c   Park, Hee Juhn ^d   Lee, Kyung Tae ^a  

^a Kyung Hee University   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

^c Kyungsung University   (South Korea)

^d Sangji University   (South Korea)

Author keywords

COX 2; Hederagenin monodesmoside; iNOS and TNF ; Lipopolysaccharide; Macrophage; Nitric oxide; Prostaglandin E2

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; DELTA HEDERIN; HEDERAGENIN; KALOPANAX PICTUS EXTRACT; KALOPANAXAPONIN I; KALOPANAXSAPONIN A; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PLANT EXTRACT; PROSTAGLANDIN E2; SAPINDOSIDE C; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; DRUG DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOENZYME; KALOPANAX SAPONIN A; NITRITE; NONSTEROID ANTIINFLAMMATORY AGENT; NOS2 PROTEIN, MOUSE; OLEANOLIC ACID; PROSTAGLANDIN SYNTHASE; SAPONIN;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BARK; CELL STRAIN; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; IN VITRO STUDY; KALOPANAX PICTUS; MACROPHAGE; MEDICINAL PLANT; MOUSE; NONHUMAN; PLANT STEM; PROTEIN EXPRESSION; ANIMAL; ARALIACEAE; BIOSYNTHESIS; CELL LINE; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; ENZYME INDUCTION; ENZYMOLOGY; ISOLATION AND PURIFICATION; METABOLISM;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARALIACEAE; CELL LINE; CELL SURVIVAL; CYCLOOXYGENASE 2; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; ISOENZYMES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; OLEANOLIC ACID; PLANT BARK; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SAPONINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036549816     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.25.472     Document Type: Article

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