Antinociceptive and anti-rheumatoidal effects of Kalopanax pictus extract and its saponin components in experimental animals

Journal of Ethnopharmacology

Volumn 79, Issue 2, 2002, Pages 199-204

  Choi, Jongwon ^a   Huh, Keun ^b   Kim, Suk Hwan ^c   Lee, Kyung Tae ^d   Park, Hee Juhn ^e   Han, Yong Nam ^f  

^a Kyungsung University   (South Korea)

^b Yeungnam University   (South Korea)

^c Dong A University   (South Korea)

^d Kyung Hee University   (South Korea)

^e Sangji University   (South Korea)

^f Seoul National University   (South Korea)

Author keywords

Antinociceptive; Freund's adjuvant reagent; Kalopanax pictus; Kalopanaxsaponin; LD50; Rheumatoidal arthritis

Indexed keywords

ACETIC ACID ETHYL ESTER; BUTANOL; CHLOROFORM; FREUND ADJUVANT; KALOPANAXSAPONIN A; KALOPANAXSAPONIN B; KALOPANAXSAPONIN H; KALOPANAXSAPONIN I; KALOPANAXSAPONIN K; KININ; METHANOL; PLANT EXTRACT; TRYPSIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN ANTIBODY REACTION; ANTINOCICEPTION; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; EDEMA; EXPERIMENTAL ANIMAL; HOT PLATE TEST; KALOPANAX PICTUS; LD 50; MALE; MOUSE; NONHUMAN; PLANT; PROTEIN SYNTHESIS; RHEUMATOID ARTHRITIS; WRITHING TEST;

ANALGESICS; ANIMALS; ANTIRHEUMATIC AGENTS; ARALIACEAE; ARTHRITIS, EXPERIMENTAL; DRUG EVALUATION, PRECLINICAL; MALE; MICE; MICE, INBRED ICR; OLEANOLIC ACID; PAIN MEASUREMENT; PHYTOTHERAPY; PLANT BARK; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SAPONINS;

EID: 0036172787     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(01)00383-X     Document Type: Article

References (16)

1. Activation, inhibition and protection of tryptic and α-chymotryptic activity by normal human serum
2. Determination of the molecular weight of new trypsin inhibitors with the aid of sephadex gel filtration
3. Metabolism of kalopanaxsaponin B and H by human intestinal bacteria and antidiabetic activity of their metabolites
4. Growth inhibitory activities of kalopanaxsaponins A and I against human pathogenic fungi
5. Triterpenoidal saponins from the leaves of Kalopanax pictum var. chinense
6. Essential moiety for antimutagenic and cytotoxic activity of hederagenin monodesmosides and bisdesmosides isolated from the stem bark of Kalopanax pictus
7. Proteinase inhibitors suppress the formation of granulation tissue in the carageenin-induced inflammation
8. Anti-inflammatory effect of proteinase inhibitors suppression on carageenin-induced inflammation in rats
9. A potent anti-diabetic agent from Kalopanax pictus
10. Protective effects of syringin isolated from Kalopanax pictus on galactosamine induced hepatotoxicity
11. Studies on the constituents of the stem bark of Kalopanax pictus
12. Saponins from roots of Kalopanax septemlobus (Thunb.) Koidz, Ciqiu: Structures of kalopanax-saponins C, D, E and F
13. The use of change in capillary permeability to distinguish between narcotic and analgesic