Glycolic acid inhibits enzymatic, hemorrhagic and edema-inducing activities of BaP1, a P-I metalloproteinase from Bothrops asper snake venom: Insights from docking and molecular modeling

Toxicon

Volumn 71, Issue , 2013, Pages 41-48

  Pereañez, Jaime Andrés ^a   Patiño, Arley Camilo ^a   Rey Suarez, Paola ^a   Núñez, Vitelbina ^a   Henao Castañeda, Isabel Cristina ^a   Rucavado, Alexandra ^b  

^a UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^b UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

BaP1; Bothrops asper; Glycolic acid; Local tissue damage; Metalloproteinase

Indexed keywords

AZOCASEIN; BAP1 PROTEIN; CASEIN; GLYCOLIC ACID; METALLOPROTEINASE; SNAKE VENOM; UNCLASSIFIED DRUG; ZINC ION;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BOTHROPS; BOTHROPS ASPER; CHELATION; CONTROLLED STUDY; ENVENOMATION; ENZYME ACTIVE SITE; FLUORESCENCE; FOOT EDEMA; HYDROGEN BOND; IC 50; MOLECULAR DOCKING; MOLECULAR MODEL; MOUSE; MUSCLE BLEEDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SKIN BLEEDING;

BAP1; BOTHROPS ASPER; GLYCOLIC ACID; LOCAL TISSUE DAMAGE; METALLOPROTEINASE;

ANIMALS; BOTHROPS; CASEINS; CATALYTIC DOMAIN; CHELATING AGENTS; EDEMA; GLYCOLATES; HEMORRHAGE; INHIBITORY CONCENTRATION 50; METALLOENDOPEPTIDASES; MICE; MOLECULAR DOCKING SIMULATION; MUSCLE, SKELETAL; PROTEOLYSIS; SKIN; SNAKE BITES; SNAKE VENOMS; ZINC;

BOTHROPS ASPER;

EID: 84879526601     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2013.05.013     Document Type: Article

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