Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom

Toxicon

Volumn 36, Issue 11, 1998, Pages 1529-1538

  Gutiérrez, José Mara ^a   León, Guillermo ^a   Rojas, Gustavo ^a   Lomonte, Bruno ^a   Rucavado, Alexandra ^a   Chaves, Fernando ^a  

^a UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; METALLOPROTEINASE; PHOSPHOLIPASE A2; SNAKE VENOM; VENOM ANTISERUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; BLEEDING; CONFERENCE PAPER; CONTROLLED STUDY; COSTA RICA; DIFFUSION; DRUG EFFICACY; EDEMA; ENVENOMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SNAKE; TISSUE INJURY; TISSUE NECROSIS;

ANIMALS; ANTIVENINS; BOTHROPS; CROTALID VENOMS; EDEMA; FORECASTING; IMMUNOGLOBULIN E; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOTHERAPY; MICE; SNAKE BITES;

EID: 0344447110     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(98)00145-7     Document Type: Conference Paper

References (58)

1. Bjarnason J. B., Fox J. W. Hemorrhagic metalloproteinases from snake venoms. Pharmacol. Ther. 62:1994;325-372.
2. Bjarnason J. B., Barish A., Direnzo G. S., Campbell R., Fox J. W. Kallikrein-like enzymes from Crotalus atrox venom. J. Biol. Chem. 258:1983;12566-12573.
3. Bogarín G., Segura E., Durán G., Lomonte B., Rojas G., Gutiérrez J. M. Evaluación de la capacidad de cuatro antivenenos comerciales para neutralizar el veneno de la serpiente Bothrops asper (terciopelo) de Costa Rica. Toxicon. 33:1995;1242-1245.
4. Borkow G., Gutiérrez J. M., Ovadia M. Inhibition of the hemorrhagic activity of Bothrops asper venom by a novel neutralizing mixture. Toxicon. 35:1997;865-877.
5. Cardoso J. L. C., Fan H. W., Franca F. O. S., Jorge M. T., Leite R. P., Nishioka S. A., Avila A., Sano-Martins I. S., Tomy S. C., Santoro M. L., Chudzinski A. M., Castro S. C. B., Kamiguti A. S., Kelen E. M. A., Hirata M. H., Mirandola R. M. S., Theakston R. D. G., Warrell D. A. Randomized comparative trial of three antivenoms in the treatment of envenoming by lance-headed vipers (Bothrops jararaca) in Sao Paulo, Brazil. Quart. J. Med. 86:1993;315-325.
6. Chaves F., Barboza M., Gutiérrez J. M. Pharmacological study of edema induced by venom of the snake Bothrops asper (terciopelo) in mice. Toxicon. 33:1995;31-39.
7. Choumet, V., Audebert, F., Riviere, G., Sorkine, M., Urtizberea, M., Sabouraud, A., Scherrmann, J. M. and Bon, C. (1996) Toxicokinetics of Vipera aspis envenoming and antivenom therapy. In Envenomings and Their Treatments, eds C. Bon and M. Goyffon, pp. 127-133. Editions Fondation Marcel Mérieux, Lyon.
8. Fan, H. W. and Cardoso, J. L. (1995) Clinical toxicology of snake bites in South America. In Handbook of Clinical Toxicology of Animal Venoms and Poisons, eds J. Meier and J. White, pp. 667-688. CRC Press, Boca Raton.
9. Garfin S. R., Castilonia R. R., Mubarak S. J., Hargens A. R., Akeson W. H., Russell F. E. The effect of antivenin on intramuscular pressure elevations induced by rattlesnake venom. Toxicon. 23:1985;677-680.
10. Gutiérrez, J. M. (1995) Clinical toxicology of snakebite in Central America. In Handbook of Clinical Toxicology of Animal Venoms and Poisons, eds J. Meier and J. White, pp. 645-665. CRC Press, Boca Raton.
11. 2 Enzymes. Structure, Function and Mechanism, ed. R. M. Kini, pp. 321-352. Wiley, Chichester.
12. Gutiérrez J. M., Arroyo O., Bolaños R. Mionecrosis, hemorragia y edema inducidos por el veneno de Bothrops asper en ratón blanco. Toxicon. 18:1980;603-610.
13. Gutiérrez J. M., Chaves F., Bolaños R., Cerdas L., Rojas E., Arroyo O., Portilla E. Neutralización de los efectos locales del veneno de Bothrops asper por un antiveneno polivalente. Toxicon. 19:1981;493-500.
14. Gutiérrez J. M., Ownby C. L., Odell G. V. Pathogenesis of myonecrosis induced by crude venom and a myotoxin of Bothrops asper. Exp. Mol. Pathol. 40:1984;367-379.
15. Gutiérrez J. M., Gené J. A., Rojas G., Cerdas L. Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake venoms by a polyvalent antivenom. Toxicon. 23:1985;887-893.
16. Gutiérrez J. M., Rojas G., Lomonte B., Gené J. A., Cerdas L. Comparative study of the edema-forming activity of Costa Rican snake venoms and its neutralization by a polyvalent antivenom. Comp. Biochem. Physiol. 85C:1986;171-175.
17. Gutiérrez J. M., Rojas G., Cerdas L. Ability of a polyvalent antivenom to neutralize the venom of Lachesis muta melanocephala, a new Costa Rican subspecies of the bushmaster. Toxicon. 25:1987;713-720.
18. Gutiérrez J. M., Rojas G., Lomonte B., Gené J. A., Chaves F., Alvarado J., Rojas E. Standardization of assays for testing the neutralizing ability of antivenoms. Toxicon. 28:1990;1127-1129.
19. Ismail, M. and Abd-Elsalam, M. A. (1996) Serotherapy of scorpion envenoming: Pharmacokinetics of antivenoms and a critical assessment of their usefulness. In: Envenomings and Their Treatments, eds C. Bon and M. Goyffon, pp. 135-153. Editions Fondation Marcel Mérieux, Lyon.
20. Kondo H., Kondo S., Ikezawa H., Murata R., Ohsaka A. Studies on the quantitative method for determination of hemorrhagic activity of Habu snake venom. Jpn. J. Med. Sci. Biol. 13:1960;43-51.
21. 2 polyvalent antivenoms do not differ in their ability to neutralize hemorhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom. Toxicon. 35:1997;1627-1637.
22. 2EDTA of local tissue damage induced by Bothrops asper venom: Application in horse immunization for antivenom production. Toxicon 36, 321-331.
23. 2 myotoxin inhibitor from the plasma of the snake Bothrops asper. Biochem. J. 326:1997;853-859.
24. Lomonte B., Kahan L. Production and partial characterization of monoclonal antibodies to Bothrops asper (terciopelo) myotoxin. Toxicon. 26:1988;675-689.
25. Lomonte B., Gutiérrez J. M. A new muscle-damaging toxin, myotoxin II, from the venom of the snake Bothrops asper (terciopelo). Toxicon. 27:1989;725-733.
26. Lomonte B., Gutiérrez J. M., Rojas G., Calderón L. Quantitation by enzyme-immunoassay of antibodies against Bothrops myotoxins in four commercially-available antivenoms. Toxicon. 29:1991;695-702.
27. 2 from the venom of the snake Bothrops asper by monoclonal antibodies. Toxicon. 30:1992;239-245.
28. Lomonte B., Tarkowski A., Hanson L. A. Host response to Bothrops asper snake venom. Analysis of edema formation, inflammatory cells and cytokine release in a mouse model. Inflammation. 17:1993;93-105.
29. Lomonte B., Gutiérrez J. M., Romero M., Núñez J., Tarkowski A., Hanson L. A. An MTT-based method for the in vivo quantification of myotoxic activity of snake venoms and its neutralization by antibodies. J. Immunol. Methods. 161:1993;231-237.
30. Lomonte B., Lundgren J., Johansson B., Bagge U. The dynamics of local tissue damage induced by Bothrops asper snake venom and myotoxin II on the mouse cremaster muscle: An intravital and electron microscopic study. Toxicon. 32:1994;41-55.
31. 2 from Bothrops asper snake venom by glycosaminoglycans of the heparin/heparan sulfate family. Biochem. Pharmacol. 47:1994;1509-1518.
32. 2 from Bothrops asper snake venom. Identification of a heparin-binding and cytolytic toxin region by the use of synthetic peptides and molecular modeling. J. Biol. Chem. 269:1994;29867-29873.
33. 2 antivenoms in the neutralization of hemorrhagic activity of Vipera berus snake venom in mice. Toxicon. 34:1996;1197-1202.
34. Mebs D., Ownby C. L. Myotoxic components of snake venoms: Their biochemical and biological activities. Pharmacol. Ther. 48:1990;223-236.
35. Melo P. A., Homsi-Brandeburgo M. I., Giglio J. R., Suárez Kurtz G. Antagonism of the myotoxic effect of Bothrops jararacussu venom and Bothropstoxin by polyanions. Toxicon. 31:1993;285-291.
36. Melo P. A., do Nascimento M. C., Mors W. B., Suárez-Kurtz G. Inhibition of the myotoxic and hemorrhagic activities of crotalid venoms by Eclipta prostrata (Asteraceae) extracts and constituents. Toxicon. 32:1994;595-603.
37. 2. Basic and Clinical Aspects in Inflammatory Diseases, eds W. Uhl, T. J. Nevalainen and M. W. Buchler, pp. 140-145. Karger, Basel.
38. Moreira L., Gutiérrez J. M., Borkow G., Ovadia M. Ultrastructural alterations in mouse capillary blood vessels after experimental injection of venom from the snake Bothrops asper (terciopelo). Exp. Mol. Pathol. 57:1992;124-133.
39. Mors W. B., Nascimento M. C., Parente J. P., Da Silva M. H., Melo P. A., Suárez Kurtz G. Neutralization of lethal and myotoxic activities of South American rattlesnake venom by extracts and constituents of the plant Eclipta prostrata (Asteraceae). Toxicon. 27:1989;1003-1009.
40. Moura da Silva A. M., Laing G. D., Paine M. J. I., Dennison J. M. T. J., Politi V., Crampton J. M., Theakston R. D. G. Processing of pro-tumor necrosis factor-α by venom metalloproteinases: A hypothesis explaining local tissue damage following snake bite. Eur. J. Immunol. 26:1996;2000-2005.
41. Ownby, C. L. (1982) Pathology of rattlesnake envenomation. In Rattlesnake Venoms. Their Actions and Treatment, ed. A. T. Tu, pp. 163-209. Marcel Dekker, New York.
42. Ownby C. L., Colberg T. R., Odell G. V. A new method for quantitating hemorrhage induced by rattlesnake venoms: Ability of polyvalent antivenom to neutralize hemorrhagic activity. Toxicon. 22:1984;227-233.
43. Ownby C. L., Gutiérrez J. M., Colberg T., Odell G. V. Quantitation of myonecrosis induced by myotoxin a from prairie rattlesnake (Crotalus viridis viridis) venom. Toxicon. 20:1982;877-885.
44. Preston S., Davis C. E., Harris J. B. The assessment of muscle fibre loss after the injection of the venom of Notechis scutatus (Australian tiger snake). Toxicon. 28:1990;201-214.
45. Riviere G., Choumet V., Audebert F., Sabouraud A., Debray M., Scherrmann J. M., Bon C. Effect of antivenom on venom pharmacokinetics in experimentally envenomed rabbits: Toward an optimization of antivenom therapy. J. Pharmacol. Exp. Ther. 281:1997;1-8.
46. Rojas G., Gutiérrez J. M., Gené J. A., Gómez M., Cerdas L. Neutralización de las actividades tóxicas y enzimáticas de cuatro venenos de serpientes de Guatemala y Honduras por el antiveneno polivalente producido en Costa Rica. Rev. Biol. Trop. 35:1987;59-67.
47. Rothschild, A. M. and Rothschild, Z. (1979) Liberation of pharmacologically-active substances by snake venoms. In Snake Venoms, ed. C. Y. Lee, pp. 591-628. Springer Verlag, Berlin.
48. Rucavado A., Lomonte B. Neutralization of myonecrosis, hemorrhage and edema induced by Bothrops asper snake venom by homologous and heterologous pre-existing antibodies in mice. Toxicon. 34:1996;567-577.
49. Teng C. M., Wang J. P., Peng H. C., Ouyang C. Edema-producing proteins isolated from Trimeresurus mucrosquamatus snake venom. Toxicon. 27:1989;899-905.
50. Theakston, R. D. G. (1996) Snake bite: The kinetics of envenoming and therapy. In Envenomings and Their Treatments, eds C. Bon and M. Goyffon, pp. 117-126. Editions Fondation Marcel Mérieux, Lyon.
51. Theakston R. D. G., Reid H. A. Development of simple standard assay procedures for the characterization of snake venoms. Bull. W.H.O. 61:1983;949-956.
52. Theakston R. D. G., Laing G. D., Fielding C. M., Freire Lascano A., Touzet J. M., Vallejo F., Guderian R. H., Nelson S. J., Wuster W., Richards A. M., Rumbea Guzmán J., Warrell D. A. Treatment of snake bites by Bothrops species and Lachesis muta in Ecuador: Laboratory screening of candidate antivenoms. Trans. Royal Soc. Trop. Med. Hyg. 89:1995;550-554.
53. Trebien H. A., Calixto J. B. Pharmacological evaluation of rat paw edema induced by Bothrops jararaca venom. Agents Actions. 26:1989;292-300.
54. Warrell, D. A. (1996) Clinical features of envenoming from snake bites. In Envenomings and Their Treatment, eds C. Bon and M. Goyffon, pp. 63-76. Editions Fondation Marcel Mérieux, Lyon.
55. Warrell, D. A. (1997) Geographical and intraspecies variation in the clinical manifestations of envenoming by snakes. In: Venomous Snakes. Ecology, Evoilution and Snakebite, eds R. S. Thorpe, W. Wuster and A. Malhorta, pp. 189-203. Clarendon Press, New York.
56. World Health Organization (1981) Progress in the characterization of venoms and standardization of antivenoms. WHO Offset Publication No. 58, Geneva.
57. Xue C. B., He X., Roderick J., DeGrado W. F., Decicco C., Copeland R. A. Potent matrix metalloproteinase inhibitors: Amino-carboxylate compounds containing modifications of the P1 residue. Bioorg. Med. Chem. Lett. 4:1996;379-384.
58. Yamakawa, M., Nozaki, M. and Hokama, Z. (1976) Fractionation of Sakishima-habu (Trimeresurus elegans) venom and lethal, hemorrhagic and edema-forming activities of the fractions. In Animal, Plant and Microbial Toxins, eds A. Ohsaka, K. Hayashi and Y. Sawai, Vol I, pp. 97-109. Plenum Press, New York.