Investigating the suspension culture on aggregation and function of mouse pancreatic β-cells

Journal of Biomedical Materials Research - Part A

Volumn 101 A, Issue 8, 2013, Pages 2273-2282

  Yang, Kai Chiang ^a,b   Wu, Chang Chin ^c,d   Yang, Shu Hua ^c   Chiu, Chien Chang ^c,e   Sumi, Shoichiro ^b   Lee, Hsuan Shu ^c,e  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b KYOTO UNIVERSITY   (Japan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^d EN CHU KONG HOSPITAL   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

aggregation; pancreatic beta cell; pseudoislet; suspension culture

Indexed keywords

BETA CELL; BIOLOGICAL PERFORMANCE; GLUCOSE TOLERANCE TEST; GLUCOSE-STIMULATED INSULIN SECRETIONS; HIERARCHICAL STRUCTURES; INSULIN-PRODUCING CELLS; PSEUDOISLET; SUSPENSION CULTURES;

AGGLOMERATION; CELL CULTURE; COLLAGEN; GLUCOSE; INSULIN; MAMMALS; PHYSIOLOGY; SUBSTRATES;

CELLS;

COLLAGEN TYPE 4; CONNEXIN 36; GLUCOSE; STREPTOZOCIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL AGGREGATION; CELL DEATH; CELL FUNCTION; CELL STIMULATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HISTOLOGY; INSULIN BLOOD LEVEL; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; STREPTOZOCIN DIABETES; SURVIVAL RATE; SUSPENSION CELL CULTURE; WEIGHT GAIN; WESTERN BLOTTING;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CELL CULTURE TECHNIQUES; CELL SURVIVAL; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; MICE, INBRED C57BL; PANCREAS;

EID: 84879506251     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34547     Document Type: Article

References (42)

1. Kelly C, McClenaghan NH, Flatt PR,. Role of islet structure and cellular interactions in the control of insulin secretion. Islets 2011; 3: 41-47.
2. Bavamian S, Klee P, Britan A, Populaire C, Caille D, Cancela J, Charollais A, Meda P,. Islet-cell-to-cell communication as basis for normal insulin secretion. Diabetes Obes Metabol 2007; 9: 118-132.
3. Charpantier E, Cancela J, Meda P,. Beta cells preferentially exchange cationic molecules via connexin 36 gap junction channels. Diabetologia 2007; 50: 2332-2341.
4. Wojtusciszyn A, Armanet M, Morel P, Berney T, Bosco D,. Insulin secretion from human beta cells is heterogeneous and dependent on cell-to-cell contacts. Diabetologia 2008; 51: 1843-1852.
5. Bosco D, Rouiller DG, Halban PA,. Differential expression of E-cadherin at the surface of rat beta-cells as a marker of functional heterogeneity. J Endocrinol 2007; 194: 21-29.
6. Michon L, Nlend Nlend R, Bavamian S, Bischoff L, Boucard N, Caille D, Cancela J, Charollais A, Charpantier E, Klee P, Peyrou M, Populaire C, Zulianello L, Meda P,. Involvement of gap junctional communication in secretion. Biochim Biophys Acta 2005; 1719: 82-101.
7. Yang KC, Qi Z, Shirouza Y, Lu DH, Yanai G, Lee HS, Sumi S,. Cell coupling regulates Ins1, Pdx-1 and MafA to promote insulin secretion in mouse pancreatic beta cells. Process Biochemistry 2011; 46: 1853-1860.
8. Daoud J, Rosenberg L, Tabrizian M,. Pancreatic islet culture and preservation strategies: Advances, challenges, and future outlook. Cell Transplant 2010; 19: 1523-1535.
9. Noguchi H,. Pancreas procurement and preservation for islet transplantation: personal considerations. J Transplant 2011; 2011: 783168.
10. Noguchi H, Naziruddin B, Jackson A, Shimoda M, Ikemoto T, Fujita Y, Chujo D, Takita M, Kobayashi N, Onaca N, Levy MF, Matsumoto S,. Low-temperature preservation of isolated islets is superior to conventional islet culture before islet transplantation. Transplantation 2010; 89: 47-54.
11. Zhi ZL, Liu B, Jones PM, Pickup JC,. Polysaccharide multilayer nanoencapsulation of insulin-producing beta-cells grown as pseudoislets for potential cellular delivery of insulin. Biomacromolecules 2010; 11: 610-616.
12. Kelly C, Guo H, McCluskey JT, Flatt PR, McClenaghan NH,. Comparison of insulin release from MIN6 pseudoislets and pancreatic islets of Langerhans reveals importance of homotypic cell interactions. Pancreas 2010; 39: 1016-1023.
13. Luther MJ, Davies E, Muller D, Harrison M, Bone AJ, Persaud SJ, Jones PM,. Cell-to-cell contact influences proliferative marker expression and apoptosis in MIN6 cells grown in islet-like structures. Am J Physiol Endocrinol Metab 2005; 288: E502-E509.
14. Yamamoto Y, Nishigaki M, Kato N, Hayashi M, Shiba T, Mori Y, Kobayashi T, Kazuma K,. Knowledge and demand for information about islet transplantation in patients with type 1 diabetes. J Transplant 2011; 2011: 136298.
15. Meivar-Levy I, Sapir T, Berneman D, Weissbach T, Polak-Charcon S, Ravassard P, Tzakis AG, Mor E, Ricordi C, Ferber S,. Human liver cells expressing albumin and mesenchymal characteristics give rise to insulin-producing cells. J Transplant 2011; 2011: 252387.
16. Chai C, Leong KW,. Biomaterials approach to expand and direct differentiation of stem cells. Mol Ther 2007; 15: 467-480.
17. Chawla M, Bodnar CA, Sen A, Kallos MS, Behie LA,. Production of islet-like structures from neonatal porcine pancreatic tissue in suspension bioreactors. Biotechnol Prog 2006; 22: 561-567.
18. Chang CF, Hsu KH, Chiou SH, Ho LL, Fu YS, Hung SC,. Fibronectin and pellet suspension culture promote differentiation of human mesenchymal stem cells into insulin producing cells. J Biomed Mater Res A 2008; 86: 1097-1105.
19. Hwang JW, Lee BR, Jung MJ, Jung HS, Hwang YH, Kim MJ, Lee SH, Lee DY,. Functional clustering of pancreatic islet cells using concave microwell array. Macromolecular Research 2011; 19: 1320-1326.
20. Persaud SJ, Arden C, Bergsten P, Bone AJ, Brown J, Dunmore S, Harrison M, Hauge-Evans A, Kelly C, King A, Maffucci T, Marriott CE, McClenaghan N, Morgan NG, Reers C, Russell MA, Turner MD, Willoughby E, Younis MY, Zhi ZL, Jones PM,. Pseudoislets as primary islet replacements for research: report on a symposium at King's College London, London UK. Islets 2010; 2: 236-239.
21. Yang KC, Qi Z, Wu CC, Shirouzu Y, Lin FH, Yanai G, Sumi S,. The cytoprotection of chitosan based hydrogels in xenogeneic islet transplantation: An in vivo study in streptozotocin-induced diabetic mouse. Biochem Biophys Res Commun 2010; 393: 818-823.
22. Shirouzu Y, Gu Y, Koga M, Sakurai T, Qi M, Hiura A, Sumi S, Inoue K,. Cold preservation of islets in UW solution-with special reference to apoptosis. J Surg Res 2006; 133: 167-175.
23. Qi Z, Shen Y, Yanai G, Yang K, Shirouzu Y, Hiura A, Sumi S,. The in vivo performance of polyvinyl alcohol macro-encapsulated islets. Biomaterials 2010; 31: 4026-4031.
24. Nagata N, Gu Y, Hori H, Balamurugan AN, Touma M, Kawakami Y, Wang W, Baba TT, Satake A, Nozawa M, Tabata Y, Inoue K,. Evaluation of insulin secretion of isolated rat islets cultured in extracellular matrix. Cell Transplant 2001; 10: 447-451.
25. Kaido T, Yebra M, Cirulli V, Montgomery AM,. Regulation of human beta-cell adhesion, motility, and insulin secretion by collagen IV and its receptor alpha1beta1. J Biol Chem 2004; 279: 53762-53769.
26. Eiraku M, Watanabe K, Matsuo-Takasaki M, Kawada M, Yonemura S, Matsumura M, Wataya T, Nishiyama A, Muguruma K, Sasai Y,. Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. Cell Stem Cell 2008; 3: 519-532.
27. 2+ and insulin secretory responses of MIN6 pseudoislets. Diabetes 1999; 48: 1402-1408.
28. Huang HH, Novikova L, Williams SJ, Smirnova IV, Stehno-Bittel L,. Low insulin content of large islet population is present in situ and in isolated islets. Islets 2011; 3: 6-13.
29. Fujita Y, Takita M, Shimoda M, Itoh T, Sugimoto K, Noguchi H, Naziruddin B, Levy MF, Matsumoto S,. Large human islets secrete less insulin per islet equivalent than smaller islets in vitro. Islets 2011; 3: 1-5.
30. Nam KH, Yong W, Harvat T, Adewola A, Wang S, Oberholzer J, Eddington DT,. Size-based separation and collection of mouse pancreatic islets for functional analysis. Biomed Microdevices 2010; 12: 865-874.
31. Giuliani M, Moritz W, Bodmer E, Dindo D, Kugelmeier P, Lehmann R, Gassmann M, Groscurth P, Weber M,. Central necrosis in isolated hypoxic human pancreatic islets: Evidence for postisolation ischemia. Cell Transplant 2005; 14: 67-76.
32. Lai Y, Brandhorst H, Hossain H, Bierhaus A, Chen C, Bretzel RG, Linn T,. Activation of NFκB dependent apoptotic pathway in pancreatic islet cells by hypoxia. Islets 2009; 1: 19-25.
33. Chiang TS, Yang KC, Zheng SK, Chiou LL, Hsu WM, Lin FH, Huang GT, Lee HS,. The prediction of drug metabolism using scaffold-mediated enhancement of the induced cytochrome P450 activities in fibroblasts by hepatic transcriptional regulators. Biomaterials 2012; 33: 5187-5197.
34. MacGregor RR, Williams SJ, Tong PY, Kover K, Moore WV, Stehno-Bittel L,. Small rat islets are superior to large islets in in vitro function and in transplantation outcomes. Am J Physiol Endocrinol Metabol 2006; 290: E771-E779.
35. Molnár C, Essand M, Wennberg L, Berne C, Larsson E, Tufveson G, Korsgren O,. Islet engraftment and revascularization in clinical and experimental transplantation. Cell Transplant. 2012 May 8.
36. Jansson L, Carlsson PO,. Graft vascular function after transplantation of pancreatic islets. Diabetologia 2002; 45: 749-763.
37. Menger MD, Yamauchi J, Vollmar B,. Revascularization and microcirculation of freely grafted islets of Langerhans. World J Surg 2001; 25: 509-515.
38. Persaud SJ,. Pancreatic β-cell lines: Their roles in β-cell research and diabetes therapy. Adv Mol Cell Biol 1999; 29: 21-46.
39. Sweet IR, Yanay O, Waldron L, Gilbert M, Fuller JM, Tupling T, Lernmark A, Osborne WR,. Treatment of diabetic rats with encapsulated islets. J Cell Mol Med 2008; 12: 2644-2650.
40. Qi Z, Yamamoto C, Imori N, Kinukawa A, Yang KC, Yanai G, Ikenoue E, Shen Y, Shirouzu Y, Hiura A, Inoue K, Sumi S,. Immunoisolation effect of polyvinyl alcohol (PVA) macro-encapsulated islets in type 1 diabetes therapy. Cell Transplantation 2012; 21: 525-534.
41. Reers C, Hauge-Evans AC, Morgan NG, Wilcox A, Persaud SJ, Jones PM,. Down-regulation of proliferation does not affect the secretory function of transformed β-cell lines regardless of their anatomical configuration. Islets 2011; 3: 80-88.
42. Lehmann R, Zuellig RA, Kugelmeier P, Baenninger PB, Moritz W, Perren A, Clavien PA, Weber M, Spinas GA,. Superiority of small islets in human islet transplantation. Diabetes 2007; 56: 594-603.