PG201 downregulates the production of nitrite by upregulating heme oxygenase-1 expression through the control of phosphatidylinositol 3-kinase and NF-E2-related factor 2

Nitric Oxide - Biology and Chemistry

Volumn 33, Issue , 2013, Pages 42-55

  Choi, Jinyong ^a   Lee, Junsub ^a   Lee, Junghun ^a   Kim, Seon Hee ^b   Kim, Jiyoung ^a,c   Kim, Sunyoung ^a,b  

^a Seoul National University   (South Korea)

^b ViroMed Co Ltd   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Heme oxygenase 1; Inducible nitric oxide synthase; Nitrite; Nrf2; PG201; Phosphatidylinositol 3 kinase

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIOXIDANT; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRITE; PG 201; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENHANCER REGION; ENZYME INDUCTION; MACROPHAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REPORTER GENE; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALIA; MURINAE; MUS;

HEME OXYGENASE-1; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRITE; NRF2; PG201; PHOSPHATIDYLINOSITOL 3-KINASE;

ANALYSIS OF VARIANCE; ANIMALS; CELL LINE; DOWN-REGULATION; GENE EXPRESSION REGULATION; HEME OXYGENASE-1; MICE; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PHOSPHATIDYLINOSITOL 3-KINASES; PLANT EXTRACTS; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION;

EID: 84879489432     PISSN: 10898603     EISSN: 10898611     Source Type: Journal    
DOI: 10.1016/j.niox.2013.05.003     Document Type: Article

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