Epigenetic Silencing of miR-338-3p Contributes to Tumorigenicity in Gastric Cancer by Targeting SSX2IP

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Li, Pu ^a   Chen, Xuehua ^a   Su, Liping ^a   Li, Chenglong ^a   Zhi, Qiaoming ^a   Yu, Beiqin ^a   Sheng, Hong ^a   Wang, Junqing ^a   Feng, Runhua ^a   Cai, Qu ^a   Li, Jianfang ^a   Yu, Yingyan ^a   Yan, Min ^a   Liu, Bingya ^a   Zhu, Zhenggang ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 338 3P; UNCLASSIFIED DRUG; MIRN338 MICRORNA, HUMAN; REPRESSOR PROTEIN; SYNOVIAL SARCOMA X BREAKPOINT PROTEINS; TUMOR PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENICITY; CELL INVASION; CLINICAL FEATURE; CONTROLLED STUDY; CPG ISLAND; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; MIGRATION INHIBITION; MITOSIS INHIBITION; MOUSE; NONHUMAN; ONCOGENE; SSX2IP GENE; STOMACH CANCER; ANIMAL; DRUG SCREENING; GENETIC EPIGENESIS; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; NUDE MOUSE; STOMACH NEOPLASMS; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; EPIGENESIS, GENETIC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, NUDE; MICRORNAS; NEOPLASM PROTEINS; REPRESSOR PROTEINS; STOMACH NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84879467774     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066782     Document Type: Article

References (43)

1. Parkin DM, Bray F, Ferlay J, Pisani P, (2005) Global cancer statistics, 2002. CA Cancer J Clin 55: 74-108.
2. O'Hara SP, Mott JL, Splinter PL, Gores GJ, LaRusso NF, (2009) MicroRNAs: key modulators of posttranscriptional gene expression. Gastroenterology 136: 17-25.
3. Brueckner B, Stresemann C, Kuner R, Mund C, Musch T, et al. (2007) The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function. Cancer Res 67: 1419-1423.
4. Gupta GP, Massague J, (2006) Cancer metastasis: building a framework. Cell 127: 679-695.
5. Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, et al. (2004) Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 101: 2999-3004.
6. Schoof CR, Botelho EL, Izzotti A, Vasques Ldos R, (2012) MicroRNAs in cancer treatment and prognosis. Am J Cancer Res 2: 414-433.
7. Zhang B, Pan X, Cobb GP, Anderson TA, (2007) microRNAs as oncogenes and tumor suppressors. Dev Biol 302: 1-12.
8. Song JH, Meltzer SJ (2012) MicroRNAs in pathogenesis, diagnosis, and treatment of gastroesophageal cancers. Gastroenterology 143: 35-47 e32.
9. Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, et al. (2005) RAS is regulated by the let-7 microRNA family. Cell 120: 635-647.
10. Zhang HH, Wang XJ, Li GX, Yang E, Yang NM, (2007) Detection of let-7a microRNA by real-time PCR in gastric carcinoma. World J Gastroenterol 13: 2883-2888.
11. Chan SH, Wu CW, Li AF, Chi CW, Lin WC, (2008) miR-21 microRNA expression in human gastric carcinomas and its clinical association. Anticancer Res 28: 907-911.
12. Xia L, Zhang D, Du R, Pan Y, Zhao L, et al. (2008) miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int J Cancer 123: 372-379.
13. Feng R, Chen X, Yu Y, Su L, Yu B, et al. (2010) miR-126 functions as a tumour suppressor in human gastric cancer. Cancer Lett 298: 50-63.
14. Li C, Nie H, Wang M, Su L, Li J, et al. (2012) MicroRNA-409-3p regulates cell proliferation and apoptosis by targeting PHF10 in gastric cancer. Cancer Lett 320: 189-197.
15. Li CL, Nie H, Wang M, Su LP, Li JF, et al. (2012) microRNA-155 is downregulated in gastric cancer cells and involved in cell metastasis. Oncol Rep 27: 1960-1966.
16. Saba R, Goodman CD, Huzarewich RL, Robertson C, Booth SA, (2008) A miRNA signature of prion induced neurodegeneration. PLoS One 3: e3652.
17. Kos A, Olde Loohuis NF, Wieczorek ML, Glennon JC, Martens GJ, et al. (2012) A potential regulatory role for intronic microRNA-338-3p for its host gene encoding apoptosis-associated tyrosine kinase. PLoS One 7: e31022.
18. De Felice B, Guida M, Coppola C, De Mieri G, Cotrufo R, (2012) A miRNA signature in leukocytes from sporadic amyotrophic lateral sclerosis. Gene 508: 35-40.
19. Gaedcke J, Grade M, Camps J, Sokilde R, Kaczkowski B, et al. (2012) The Rectal Cancer microRNAome- microRNA Expression in Rectal Cancer and Matched Normal Mucosa. Clin Cancer Res 18: 4919-4930.
20. Fu X, Tan D, Hou Z, Hu Z, Liu G, (2012) miR-338-3p Is Down-Regulated by Hepatitis B Virus X and Inhibits Cell Proliferation by Targeting the 3′-UTR Region of CyclinD1. Int J Mol Sci 13: 8514-8539.
21. Fu X, Tan D, Hou Z, Hu Z, Liu G, et al. (2012) The Effect of miR-338-3p on HBx Deletion-Mutant (HBx-d382) Mediated Liver-Cell Proliferation through CyclinD1 Regulation. PLoS One 7: e43204.
22. Huang XH, Chen JS, Wang Q, Chen XL, Wen L, et al. (2011) miR-338-3p suppresses invasion of liver cancer cell by targeting smoothened. J Pathol 225: 463-472.
23. Lin CH, Fu ZM, Liu YL, Yang JL, Xu JF, et al. (1984) Investigation of SGC-7901 cell line established from human gastric carcinoma cells. Chin Med J (Engl) 97: 831-834.
24. Park JG, Frucht H, LaRocca RV, Bliss DP Jr, Kurita Y, et al. (1990) Characteristics of cell lines established from human gastric carcinoma. Cancer Res 50: 2773-2780.
25. Lu YY, Lu GR, Xu XL, Ee Z, Miao J, et al. (1986) [DNA transformation activity of a human gastrocarcinoma cell line]. Zhonghua Zhong Liu Za Zhi 8: 241-244.
26. Barranco SC, Townsend CM Jr, Casartelli C, Macik BG, Burger NL, et al. (1983) Establishment and characterization of an in vitro model system for human adenocarcinoma of the stomach. Cancer Res 43: 1703-1709.
27. Sekiguchi M, Sakakibara K, Fujii G, (1978) Establishment of cultured cell lines derived from a human gastric carcinoma. Jpn J Exp Med 48: 61-68.
28. Motoyama T, Hojo H, Watanabe H, (1986) Comparison of seven cell lines derived from human gastric carcinomas. Acta Pathol Jpn 36: 65-83.
29. Ke Y, Ning T, Wang B, (1994) [Establishment and characterization of a SV40 transformed human fetal gastric epithelial cell line-GES-1]. Zhonghua Zhong Liu Za Zhi 16: 7-10.
30. Chen J, Wang W, Zhang T, Ji J, Qian Q, et al. (2012) Differential expression of phospholipase C epsilon 1 is associated with chronic atrophic gastritis and gastric cancer. PLoS One 7: e47563.
31. Fabbri M, Calore F, Paone A, Galli R, Calin GA, (2013) Epigenetic Regulation of miRNAs in Cancer. Adv Exp Med Biol 754: 137-148.
32. Bandres E, Agirre X, Bitarte N, Ramirez N, Zarate R, et al. (2009) Epigenetic regulation of microRNA expression in colorectal cancer. Int J Cancer 125: 2737-2743.
33. Guinn BA, Bullinger L, Thomas NS, Mills KI, Greiner J, (2008) SSX2IP expression in acute myeloid leukaemia: an association with mitotic spindle failure in t(8;21), and cell cycle in t(15;17) patients. Br J Haematol 140: 250-251.
34. Guinn B, Greiner J, Schmitt M, Mills KI, (2009) Elevated expression of the leukemia-associated antigen SSX2IP predicts survival in acute myeloid leukemia patients who lack detectable cytogenetic rearrangements. Blood 113: 1203-1204.
35. Zhang L, Greiner J, (2011) Leukemia-associated antigens are immunogenic and have prognostic value in acute myeloid leukemia. Immunotherapy 3: 697-699.
36. Li P, Lin Y, Zhang Y, Zhu Z, Huo K, (2013) SSX2IP promotes metastasis and chemotherapeutic resistance of hepatocellular carcinoma. J Transl Med 11: 52.
37. Saxonov S, Berg P, Brutlag DL, (2006) A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters. Proc Natl Acad Sci U S A 103: 1412-1417.
38. Tsai KW, Wu CW, Hu LY, Li SC, Liao YL, et al. (2011) Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer. Int J Cancer 129: 2600-2610.
39. Kim K, Lee HC, Park JL, Kim M, Kim SY, et al. (2011) Epigenetic regulation of microRNA-10b and targeting of oncogenic MAPRE1 in gastric cancer. Epigenetics 6: 740-751.
40. Hayashi Y, Tsujii M, Wang J, Kondo J, Akasaka T, et al. (2012) CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis. Gut.
41. Asada M, Irie K, Morimoto K, Yamada A, Ikeda W, et al. (2003) ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions. J Biol Chem 278: 4103-4111.
42. Fukumoto Y, Kurita S, Takai Y, Ogita H, (2011) Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 protein. J Biol Chem 286: 43537-43548.
43. Pan Y, Bi F, Liu N, Xue Y, Yao X, et al. (2004) Expression of seven main Rho family members in gastric carcinoma. Biochem Biophys Res Commun 315: 686-691.