Effects of sirtuin 1 activation on nicotine and lipopolysaccharide-induced cytotoxicity and inflammatory cytokine production in human gingival fibroblasts

Journal of Periodontal Research

Volumn 48, Issue 4, 2013, Pages 483-492

  Park, G J ^a   Kim, Y S ^b   Kang, K L ^c   Bae, S J ^c   Baek, H S ^c   Auh, Q S ^c   Chun, Y H ^c   Park, B H ^d   Kim, E C ^b  

^a Dankook University   (South Korea)

^b School of Dentistry and Institute of Oral Biology   (South Korea)

^c Kyung Hee University   (South Korea)

^d Chonbuk National University   (South Korea)

Author keywords

Adenovirus SIRT1; Anti inflammatory; Lipopolysaccharides; Nicotine; Resvaratrol; SIRT1

Indexed keywords

AUTACOID; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN DERIVATIVE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINE; NICOTINIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN E2; PROTEIN KINASE C; PTGS2 PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE; RESVERATROL; SIRT1 PROTEIN, HUMAN; SIRTUIN 1; STILBENE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

ADENOVIRUS; ARTICLE; CELL LINE; CELL SURVIVAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; FIBROBLAST; GENE VECTOR; GENETICS; GINGIVA; HUMAN; METABOLISM; UPREGULATION;

ADENOVIRIDAE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; CELL SURVIVAL; CYCLOOXYGENASE 2; DINOPROSTONE; FIBROBLASTS; GENETIC VECTORS; GINGIVA; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKINS; LIPOPOLYSACCHARIDES; MAP KINASE KINASE 4; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NICOTINE; NICOTINIC AGONISTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; SIRTUIN 1; STILBENES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84879460447     PISSN: 00223484     EISSN: 16000765     Source Type: Journal    
DOI: 10.1111/jre.12030     Document Type: Article

References (57)

1. Page RC. The role of inflammatory mediators in the pathogenesis of periodontal disease. J Periodontal Res 1991;26:230-242.
2. van Winkelhoff AJ, van Appelmelk BJ, Kippuw N, de Graaff J. K-antigens in Porphyromonas gingivalis are associated with virulence. Oral Microbiol Immunol 1988;8:259-265.
3. Agarwal S, Baran C, Piesco NP et al. Synthesis of proinflammatory cytokines by human gingival fibroblasts in response to lipopolysaccharides and interleukin-1 beta. J Periodontal Res 1995;30:382-389.
4. Wang PL, Ohura K. Porphyromonas gingivalis lipopolysaccharide signaling in gingival fibroblasts-CD14 and Toll-like receptors. Crit Rev Oral Biol Med 2002;13:132-142.
5. Takada H, Mihara J, Morisaki I, Hamada S. Induction of interleukin-1 and -6 in human gingival fibroblast cultures stimulated with Bacteroides lipopolysaccharides. Infect Immun 1991;59:295-301.
6. Martinez-Canut P, Lorca A, Magan R. Smoking and periodontal disease severity. J Clin Periodontol 1995;22:743-749.
7. Grossi SG, Genco RJ, Machtei EE et al. Assessment of risk for periodontal disease. II. Risk indicators for alveolar bone loss. J Periodontol 1995;66:23-29.
8. Darby IB, Hodge PJ, Riggio MP, Kinane DF. Clinical and microbiological effect of scaling and root planning in smoker and non-smoker chronic and aggressive periodontitis patients. J Clin Periodontol 2005;32:200-206.
9. Pabst MJ, Pabst KM, Collier JA et al. Inhibition of neutrophil and monocyte defensive functions by nicotine. J Periodontol 1995;66:1047-1055.
10. Ginnopoulou C, Geinoz A, Cimasoni G. Effects of nicotine on periodontal ligament fibroblats in vitro. J Clin Periodontol 1999;26:49-55.
11. Kang SW, Park HJ, Ban JY, Chung JH, Chun GS, Cho JO. Effects of nicotine on apoptosis in human gingival fibroblasts. Arch Oral Biol 2011;56:1091-1097.
12. San Miguel SM, Opperman LA, Allen EP, Zielinski J, Svoboda KK. Antioxidants counteract nicotine and promote migration via RacGTP in oral fibroblast cells. J Periodontol 2010;81:1675-1690.
13. Lee HJ, Pi SH, Kim Y et al. Effects of nicotine on antioxidant defense enzymes and RANKL expression in human periodontal ligament cells. J Periodontol 2009;80:1281-1288.
14. Lee SI, Kang KI, Hee Y, Lee YM, Kim EC. Endoplasmic reticulum stress modulates nicotine-induced extracellular matrix degradation in human periodontal ligament cells. J Periodontal Res 2012;47:299-308.
15. Tanaka H, Tanabe N, Shoji M et al. Nicotine and lipopolysaccharide stimulate the formation of osteoclast-like cells by increasing macrophage colony-stimulating factor and prostaglandin E2 production by osteoblasts. Life Sci 2006;78:1733-1740.
16. Shoji M, Tanabe N, Mitsui N et al. Lipopolysaccharide enhances the production of nicotine-induced prostaglandin E2 by an increase in cyclooxygenase-2 expression in osteoblasts. Acta Biochim Biophys Sin 2007;39:163-172.
17. Almasri A, Wisithphrom K, Windsor LJ, Olson B. Nicotine and lipopolysaccharide affect cytokine expression from gingival fibroblasts. J Periodontol 2007;78:533-541.
18. Wendell KJ, Stein SH. Regulation of cytokine production in human gingival fibroblasts following treatment with nicotine and lipopolysaccharide. J Periodontol 2001;72:1038-1044.
19. Pi SH, Jeong GS, Oh HW et al. Heme oxygenase-1 mediates nicotine- and lipopolysaccharide-induced COX-2 and iNOS expression in human periodontal ligament cells. J Periodontal Res 2010;45:177-183.
20. Jeong GS, Lee SH, Jeong SN, Kim YC, Kim EC. Anti-inflammatory effects of apigenin on nicotine- and lipopolysaccharide-stimulated human periodontal ligament cells via heme oxygenase-1. Int Immunopharmacol 2009;9:1374-1380.
21. Lee YM, Shin SI, Shin KS et al. The role of sirtuin 1 in osteoblastic differentiation in human periodontal ligament cells. J Periodontal Res 2011;46:712-721.
22. Lee SI, Min KS, Bae WJ et al. Role of SIRT1 in heat stress- and lipopolysaccharide-induced immune and defense gene expression in human dental pulp cells. J Endod 2011;37:1525-1530.
23. Kim YS, Lee YM, Park JS, Lee SK, Kim EC. SIRT1 modulates high-mobility group box 1-induced osteoclastogenic cytokines in human periodontal ligament cells. J Cell Biochem 2010;111:1310-1320.
24. Purushotham A, Schug TT, Xu Q, Surapureddi S, Guo X, Li X. Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metab 2009;9:327-338.
25. Chen J, Zhou Y, Mueller-Steiner S et al. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappa-B signaling. J Biol Chem 2005;280:40364-40374.
26. Yeung F, Hoberg JE, Ramsey CS et al. Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 2004;23:2369-2380.
27. Yang SR, Wright J, Bauter M, Seweryniak K, Kode A, Rahman I. Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-κB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging. Am J Physiol Lung Cell Mol Physiol 2007;292:L567-L576.
28. Kim SR, Lee KS, Park SJ et al. Involvement of sirtuin 1 in airway inflammation and hyperresponsiveness of allergic airway disease. J Allergy Clin Immunol 2010;125:449-460.
29. Niederer F, Ospelt C, Brentano F et al. SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Ann Rheum Dis 2011;70:1866-1873.
30. Orecchia A, Scarponi C, Di Felice F et al. Sirtinol treatment reduces inflammation in human dermal microvascular endothelial cells. PLoS ONE 2011;6:e24307.
31. O'Connor DJ, Wong RW, Rabie AB. Resveratrol inhibits periodontal pathogens in vitro. Phytother Res 2011;25:1727-1731.
32. Núñez MJ, Novío S, Balboa J, Seoane J, Suárez JA, Freire-Garabal M. Effects of resveratrol on expression of vascular endothelial growth factor in human gingival fibroblasts stimulated by periodontal pathogens. Acta Odontol Scand 2010;68:239-247.
33. Park HJ, Jeong SK, Kim SR et al. Resveratrol inhibits Porphyromonas gingivalis lipopolysaccharide-induced endothelial adhesion molecule expression by suppressing NF-kappa-B activation. Arch Pharm Res 2009;32:583-591.
34. Andreou V, D'Addario M, Zohar R et al. Inhibition of osteogenesis in vitro by a cigarette smoke-associated hydrocarbon combined with Porphyromonas gingivalis lipopolysaccharide: reversal by resveratrol. J Periodontol 2004;75:939-948.
35. Pi SH, Lee SK, Hwang YS, Choi MG, Lee SK, Kim EC. Differential expression of periodontal ligament-specific markers and osteogenic differentiation in HPV16-immortalized human gingival fibroblasts and periodontal ligament cells. J Periodontal Res 2007;42:104-113.
36. Somerman MJ, Archer SY, Imm GR, Foster RA. A comparative study of human periodontal ligament cells and gingival fbroblasts in vitro. J Dent Res 1988;67:66-70.
37. Kobayashi K, Takahashi N, Jimi E et al. Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J Exp Med 2000;191:275-286.
38. Hofbauer LC, Khosla S, Dunstan CR, Lacey DL, Boyle WJ, Riggs BL. The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption. J Bone Miner Res 2000;15:2-12.
39. Cuff MJ, McQuade MJ, Scheidt MJ, Sutherland DE, Van Dyke TE. The presence of nicotine on root surfaces of periodontally diseased teeth in smokers. J Periodontol 1989;60:564-569.
40. Hoffman D, Adams D. Carcinogenic tobacco specific N-nitrosamines in snuff and in the saliva of snuff dippers. Cancer Res 1981;41:4305-4308.
41. Benowitz NL. Clinical pharmacology of nicotine. Annu Rev Med 1986;37:21-32.
42. Hillmann G, Dogan S, Geurtsen W. Histopathological investigation of gingival tissue from patients with rapidly progressive periodontitis. J Periodontol 1998;69:195-208.
43. Kamata N, Fujimoto R, Tomonari M, Taki M, Nagayama M, Yasumoto S. Immortalization of human dental papilla, dental pulp, periodontal ligament cells and gingival fibroblasts by telomerase reverse transcriptase. J Oral Pathol Med 2004;33:417-423.
44. Imai S, Armstrong CM, Kaeberlein M, Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 2000;403:795-800.
45. Brunet A, Sweeney LB, Sturgill JF et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004;303:2011-2015.
46. Picard F, Kurtev M, Chung N et al. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature 2004;429:771-776.
47. Luo J, Nikolaev AY, Imai S et al. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 2001;107:137-148.
48. Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1a and SIRT1. Nature 2005;434:113-118.
49. Kim D, Nguyen MD, Dobbin MM et al. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J 2007;26:3169-3179.
50. Kurtiş B, Tüter G, Serdar M, Pinar S, Demirel I, Toyman U. Gingival crevicular fluid prostaglandin E(2) and thiobarbituric acid reactive substance levels in smokers and non-smokers with chronic periodontitis following phase I periodontal therapy and adjunctive use of flurbiprofen. J Periodontol 2007;78:104-111.
51. Tsai CC, Hong YC, Chen CC, Wu YM. Measurement of prostaglandin E2 and leukotriene B4 in the gingival crevicular fluid. J Dent 1998;26:97-103.
52. Williams RC, Jeffcoat MK, Howell TH et al. Altering the progression of human alveolar bone loss with the non-steroidal anti-inflammatory drug flurbiprofen. J Periodontol 1989;60:485-490.
53. Nemoto S, Fergusson MM, Finkel T. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 2004;306:2105-2108.
54. Kanfi Y, Peshti V, Gozlan YM, Rathaus M, Gil R, Cohen HY. Regulation of SIRT1 protein levels by nutrient availability. FEBS Lett 2008;582:2417-2423.
55. Panaro MA, Carofiglio V, Acquafredda A, Cavallo P, Cianciulli A. Anti-inflammatory effects of resveratrol occur via inhibition of lipopolysaccharide-induced NF-kB activation in Caco-2 and SW480 human colon cancer cells. Br J Nutr 2012;17:1-10.
56. Ahn J, Lee H, Kim S, Ha T. Resveratrol inhibits TNF-[alpha]-induced changes of adipokines in 3T3-L1 adipocytes. Biochem Biophys Res Commun 2007;364:972-977.
57. Outeiro TF, Marques O, Kazantsev A. Therapeutic role of sirtuins in neurodegenerative disease. Biochim Biophys Acta 2008;1782:363-369.